| ST Leonards Management Committee Ltd | Households | 2016 |
| ST Wyburn Management Company Limited | Real estate | 2001 |
| ST. Andrews Court, Management Company Limited | Households | 1980 |
| ST. Paul's Management (Southport) Company Limited | Households | 2006 |
| Stable Properties (Station Road) Limited | Professional & scientific | 2003 |
| Stadt UND HOF Properties Limited | Real estate | 1976 |
| Staffing Central Limited | Administrative & support | 2019 |
| Stakk Property Holdings Limited | Real estate | 2023 |
| Stamford Park Estates Holding Limited | Financial services | 2026 |
| Standby Touring Ltd | Arts & recreation | 2026 |
| Standout Campers Ltd. | Administrative & support | 2017 |
| Stanley House Properties Limited | Construction | 2004 |
| Stanley’S Inspection & Blades Ltd | Administrative & support | 2026 |
| Star Catcher Studios Limited | Information & communication | 2023 |
| Star Wars Dept. Ltd | Wholesale & retail | 2025 |
| Starbrick Group Ltd | Real estate | 2012 |
| Starbrick Limited | Real estate | 2013 |
| Stars & Stripes Limited | Hospitality | 2016 |
| Statement Drafting Services Ltd | Administrative & support | 2024 |
| Statham Medical Services Limited | Health & social care | 2013 |
| Steadicamm Limited | Professional & scientific | 2011 |
| Stem Women Limited | Administrative & support | 2020 |
| Stepahead Trading Limited | Construction | 2020 |
| Stephen Hinsley Planning Limited | Other services | 2018 |
| Steppas CLO Ltd | Wholesale & retail | 2025 |
| Sterling Leisure Services Limited | Professional & scientific | 1991 |
| Sterling Literary Services Limited | Wholesale & retail | 2026 |
| Sterling Martin Ltd | Wholesale & retail | 2021 |
| Sterling Mason Ltd | Professional & scientific | 2020 |
| Steve Bewley Design Ltd | Other services | 2007 |
| Steve Illingworth Case Management Ltd | Health & social care | 2025 |
| Steve Newman Car Sales Ltd | Wholesale & retail | 2025 |
| Steve Watson (NW) Ltd. | Construction | 2006 |
| Steve's (Tyred N' Exhausted) Limited | Administrative & support | 1998 |
| Stewart Soft Furnishing and Design Ltd | Administrative & support | 2021 |
| Stimocon Ltd | Professional & scientific | 2016 |
| Stirling Court (Southport) RTM Company Limited | Households | 2023 |
| Stokermetric Ltd | Information & communication | 2015 |
| Stokers Garage Limited | Administrative & support | 2018 |
| Stone River Limited | Construction | 2016 |
| Stoneleigh Court (Southport) RTM Company Limited | Households | 2010 |
| Storge Chung Limited | Real estate | 2022 |
| Stork Mail Limited | Wholesale & retail | 2016 |
| Stork Thermal Equipment Ltd | Manufacturing | 1961 |
| Stormspell Holdings Limited | Other services | 2021 |
| Stormspell Limited | Wholesale & retail | 1999 |
| Strategy Executive Search Ltd | Administrative & support | 2018 |
| Strawberry HR Limited | Professional & scientific | 2010 |
| Street (Management) Company Limited(The) | Households | 1986 |
| Streetlights Property Management Ltd | Households | 2023 |
| Stride-Uk Ltd | Wholesale & retail | 2016 |
| Strive Send Specialists Limited | Education | 2022 |
| Strongtech Group Ltd | Financial services | 2025 |
| Struqta Construction Limited | Construction | 2017 |
| Stuart Brown Gardening Services Ltd | Other services | 2002 |
| Stuart Lodge (Southport) Management Company Limited(The) | Households | 1978 |
| Stubbs Parkin Limited | Professional & scientific | 2004 |
| Studio Nine Group Ltd | Information & communication | 2025 |
| Studio Renton Ltd | Professional & scientific | 2018 |
| Studley Group Freeholds Limited | Households | 2017 |
| Stumps Away UK Limited | Agriculture & fishing | 2022 |
| Suckling Properties Limited | Real estate | 2024 |
| Sugarloaf Initiatives Ltd | Administrative & support | 2012 |
| Sugarush Pick N MIX Ltd | Hospitality | 2021 |
| Sukhpreet Kaur Limited | Health & social care | 2015 |
| Sukr Foods Limited | Wholesale & retail | 2025 |
| Sulli INK Limited | Other services | 2015 |
| Sultan's Pizza Limited | Hospitality | 2019 |
| Summerwood Gardens Management Company Limited | Households | 2014 |
| Summit I.T. Services & Support Limited | Information & communication | 2023 |
| Sun Construction Ltd | Construction | 2019 |
| Sun Source Brokers Limited | Financial services | 2025 |
| Sun-E Solutions Ltd. | Information & communication | 2012 |
| Suncourt Management Limited | Hospitality | 1997 |
| Sunflow Creations Limited | Information & communication | 2012 |
| Sunflowers (Southport) Ltd | Health & social care | 2017 |
| Sunningwell Resident Management Company Limited | Households | 2016 |
| Sunny Bank Wishes Ltd | Wholesale & retail | 2023 |
| Sunstrider Estates Limited | Real estate | 2021 |
| SUP Board Rental Ltd | Administrative & support | 2019 |
| Supa Rent Ltd | Real estate | 2007 |
| Supaova Ltd | Manufacturing | 2024 |
| Supastrikers Southport Ltd | Arts & recreation | 2024 |
| Support British Farmers Ltd | Wholesale & retail | 2026 |
| Support Initiatives North West Limited | Health & social care | 2015 |
| Supreme Attractions Limited | Administrative & support | 2011 |
| Sure Rope Access Ltd | Construction | 2025 |
| Surfr Ltd | Information & communication | 2018 |
| Sussex Freehold Ltd | Households | 2009 |
| Sussex Road Solar Limited | Construction | 2025 |
| Suttons Commercial (Brunswick Quay) Limited | Real estate | 1997 |
| SUV Trans Ltd | Transport & logistics | 2021 |
| SVC (Waterloo) RTM Company Limited | Households | 2019 |
| Svenstone Limited | Administrative & support | 2008 |
| SVF Consultants Limited | Professional & scientific | 2015 |
| SW Plumbing & Heating (Southport) Limited | Construction | 2025 |
| Sway Events Limited | Arts & recreation | 2018 |
| Sway Social Limited | Professional & scientific | 2025 |
| SWE Couriers Limited | Transport & logistics | 2015 |
| Sweeney Care Limited | Health & social care | 2024 |