| Residential Contractors & Constructors Ltd | Construction | 2022 |
| Resin Bound Southport Ltd | Administrative & support | 2022 |
| Responsive Computing Limited | Administrative & support | 2004 |
| Retail Accessories and Repairs Ltd | Wholesale & retail | 2024 |
| Retail Source Ltd Chester Ltd | Wholesale & retail | 2022 |
| Retreatmi Ltd | Administrative & support | 2021 |
| Retrofit Machines & Control Systems Ltd | Manufacturing | 2024 |
| REVIL8 Ltd | Professional & scientific | 2024 |
| Reviresco Homes Ltd | Real estate | 2023 |
| Revive Leisure Ltd | Hospitality | 2022 |
| Revved UP Ltd | Education | 2024 |
| Rewind Since 2001 Limited | Information & communication | 2020 |
| Reya Technologies Limited | Professional & scientific | 2024 |
| Reynolds Property Portfolio Ltd | Real estate | 2020 |
| RF NO.4 Ltd | Hospitality | 2020 |
| RG Student Properties Limited | Real estate | 2017 |
| RGH Quality Software Ltd | Information & communication | 2014 |
| RGW Properties Ltd | Real estate | 2022 |
| RH Access Group Ltd | Construction | 2023 |
| RH Ainsdale Ltd | Other services | 2017 |
| Rhea-Smith & Co Ltd | Construction | 2026 |
| Rhian Monteith Ltd | Health & social care | 2016 |
| Rhino Ecoclean Limited | Administrative & support | 2019 |
| RIC Builds Ltd | Construction | 2024 |
| Rice Creative Limited | Professional & scientific | 2005 |
| Richard Pearson Mckenzie Friend Limited | Other services | 2026 |
| Richard Skinner Financial Planning Ltd | Professional & scientific | 2011 |
| Richards Medico Legal Limited | Health & social care | 2026 |
| Richards Northwest Ltd | Hospitality | 2024 |
| Richards PUB Group Limited | Hospitality | 2025 |
| Richer Relationships Limited | Administrative & support | 2019 |
| Richmond Court Flat Management (Southport) Limited | Households | 2002 |
| Rickard Homes Ltd | Real estate | 2022 |
| Ricketys Ltd | Wholesale & retail | 2024 |
| Ridecraft (UK) Limited | Extraterritorial | 2008 |
| Ridecraft CBT Ltd | Education | 2014 |
| Ridgefield Court Management Limited | Households | 1990 |
| Riffraff Clothing Ltd | Wholesale & retail | 2018 |
| Rigby Building Contractors Limited | Construction | 1996 |
| Rigby Electrical Limited | Construction | 2000 |
| Rigby Middleton Holdings Limited | Financial services | 2020 |
| Right Place Wrong Time Ltd | Hospitality | 2024 |
| Right the Rules Limited | Extraterritorial | 2021 |
| Riley's Industrial Properties Ltd | Real estate | 2021 |
| Riley's Removals (Southport) Ltd | Administrative & support | 2016 |
| Rimmer & Howard Property Limited | Real estate | 2010 |
| Rimmer Investments Limited | Hospitality | 2026 |
| Rimmer Property Management Limited | Real estate | 2020 |
| Rimmer Roofing & Renovations Ltd | Construction | 2002 |
| Rimmer Scaffolding Limited | Construction | 2003 |
| Rimmers Court (Management) Ltd | Households | 1999 |
| Rimmers Rentals Ltd | Real estate | 2015 |
| Rimmers Windows & Conservatories Limited | Manufacturing | 1996 |
| Rise Paragliding Limited | Arts & recreation | 2020 |
| Risefield Properties Limited | Administrative & support | 2002 |
| Ritson Ground Works Limited | Construction | 2018 |
| River Contractors Ltd | Construction | 2021 |
| River Wine Limited | Wholesale & retail | 2023 |
| Riverbank Medical Services Limited | Health & social care | 2022 |
| Riverside Interiors (South Yorkshire) Limited | Manufacturing | 1998 |
| Rivertown Limited | Professional & scientific | 2010 |
| RJ Medical Services Limited | Health & social care | 2019 |
| RJB Commercial Services Ltd | Construction | 2014 |
| RJH Renovations Ltd | Construction | 2025 |
| RJL Joinery & Building Ltd | Construction | 2020 |
| RJR & HAH Properties Ltd | Real estate | 2024 |
| RKB Installations Limited | Construction | 2021 |
| Rkid Productions Ltd | Arts & recreation | 2024 |
| RKR Student Properties Limited | Real estate | 2023 |
| RLT Automotive Ltd | Wholesale & retail | 2025 |
| Rm&A Properties Ltd | Construction | 2025 |
| RN Medical NW Ltd | Health & social care | 2019 |
| Rnss Investments Ltd | Wholesale & retail | 2019 |
| Robert Samuel Bespoke Interiors Limited | Real estate | 2002 |
| Robertshaw Decorators Limited | Construction | 2006 |
| Robs Meat Ltd | Wholesale & retail | 2025 |
| Robson Limited | Construction | 2007 |
| Roby Joinery Services Limited | Construction | 2011 |
| Rocco Hayes Holdings Ltd | Arts & recreation | 2026 |
| Rock Music One Ltd | Hospitality | 2024 |
| Rock Property Holdings Limited | Real estate | 2017 |
| Rockpool Solutions Ltd | Information & communication | 2020 |
| Rodin Wealth Ltd | Financial services | 2015 |
| Rods & Dogs Ltd | Wholesale & retail | 2025 |
| Roel Miciano Surveying, Engineering & Management Services Ltd. | Professional & scientific | 2014 |
| Rofel Limited | Health & social care | 2016 |
| Roger Stevenson Limited | Arts & recreation | 1963 |
| Roisin Maguire Associates Limited | Education | 2016 |
| Roll the Dice (Bar and Entertainment) Services Ltd | Arts & recreation | 2019 |
| Romy Hollington Ltd | Information & communication | 2011 |
| Romys Swimwear Ltd | Manufacturing | 2025 |
| RON Porter Properties Limited | Real estate | 1986 |
| Rong's Ltd | Hospitality | 2021 |
| Rontech Systems Limited | Professional & scientific | 1997 |
| Roodude Ltd | Hospitality | 2023 |
| Roof Shield SW Limited | Construction | 2022 |
| Rookie 2 Rocky Events Ltd | Hospitality | 2026 |
| Rooms in the City Limited | Households | 2019 |
| Rooms@Remedy Limited | Hospitality | 2023 |
| Rooney Photography Ltd | Professional & scientific | 2014 |