| Dynamic Covings UK Limited | Wholesale & retail | 2008 |
| Dynamic Integrated Systems Ltd | Administrative & support | 2021 |
| Dynamic Quality Inspection Ltd | Construction | 2017 |
| Dynamic Rivers (Survey and Design) Ltd | Professional & scientific | 2021 |
| Dynamic Thought Systems Ltd | Education | 2022 |
| Dynamic Waterscapes Ltd | Construction | 2025 |
| E & J Trade Limited | Wholesale & retail | 2025 |
| E & K Home Improvements Ltd | Construction | 2026 |
| E and E Invests Ltd | Hospitality | 2020 |
| E B & S Shevloff Ltd | Wholesale & retail | 2019 |
| E R Technical Services (North West) Ltd | Construction | 2008 |
| E&S Recruitment Ltd | Administrative & support | 2025 |
| E&V Kitchens Ltd | Construction | 2020 |
| E-Studi Ltd | Education | 2013 |
| E.Ball & Co.(Banks)Limited | Agriculture & fishing | 1957 |
| E.J Trade Limited | Wholesale & retail | 2025 |
| Eaae Ltd | Construction | 2023 |
| Eacd Holdings Ltd | Real estate | 2011 |
| Eagle Rise Limited | Wholesale & retail | 2016 |
| Eamonn Dorgan Limited | Real estate | 2011 |
| Easoms Groundworks & Agri Ltd | Agriculture & fishing | 2026 |
| East Anglia Accountancy Ltd | Professional & scientific | 2022 |
| East Coast Chemicals Ltd | Professional & scientific | 2026 |
| East Lancashire Spine Surgery Ltd | Health & social care | 2012 |
| East Shop Retail Ltd | Wholesale & retail | 2026 |
| East Shop Southport Ltd | Wholesale & retail | 2025 |
| East Super Store Southport Ltd | Wholesale & retail | 2025 |
| East Supermarket Limited | Wholesale & retail | 2025 |
| Eastbank Properties Ltd | Real estate | 2025 |
| Easton Engineering Limited | Construction | 2015 |
| Eastward Consulting Ltd | Professional & scientific | 2018 |
| Easyelf Ltd | Wholesale & retail | 2023 |
| Eatlifecollective Ltd | Hospitality | 2022 |
| EBB & Flow Tattoo Ltd. | Arts & recreation | 2016 |
| Ebbchris Limited | Wholesale & retail | 2016 |
| EBD Holdings Ltd | Real estate | 2021 |
| Eccleston Gerring Limited | Professional & scientific | 2014 |
| Echoes Activity Cafe CIC | Health & social care | 2026 |
| Ecig & Vape Lounge Limited | Other services | 2020 |
| Eckersley's Blinds Ltd | Wholesale & retail | 2000 |
| Eclipse Consultancy Together Ltd | Health & social care | 2024 |
| Eclipse SC Enterprises Limited | Health & social care | 2018 |
| Ecliving Limited | Real estate | 2020 |
| Ecobuild Advisory Ltd | Professional & scientific | 2020 |
| Econpro Holdings Limited | Financial services | 2010 |
| Econpro Limited | Manufacturing | 2007 |
| Econpro WDS Limited | Manufacturing | 2009 |
| ECS Southport Limited | Construction | 2013 |
| ECT Anchor Street Limited | Real estate | 2019 |
| ECT Consultancy Services Ltd | Real estate | 2005 |
| Eden Ecopods Ltd | Construction | 2018 |
| Eden Energy Solutions Ltd | Professional & scientific | 2025 |
| Edmar Salt Extraction Ltd | Mining & quarrying | 2023 |
| EDS IT Services Ltd | Information & communication | 2021 |
| Edward Todd Medical Services Ltd | Health & social care | 2015 |
| Edwards Consortium Ltd | Financial services | 2025 |
| Effect Energy Ltd | Construction | 2021 |
| Efficient Sourcing Limited | Administrative & support | 2019 |
| Efor Biotech Ltd | Wholesale & retail | 2024 |
| EFT Construction Limited | Construction | 2015 |
| EFT Electrical Installations Ltd | Construction | 2016 |
| EFT Group Limited | Construction | 2015 |
| EFT Systems Limited | Other services | 1974 |
| Egdol Limited | Real estate | 2022 |
| Eggspour Ltd | Hospitality | 2023 |
| EGH241B Ltd | Hospitality | 2026 |
| Egostream (UK) Limited | Professional & scientific | 2011 |
| EH Vending & Property Ltd | Wholesale & retail | 2023 |
| EHN Properties Ltd | Real estate | 2023 |
| EJ Surfacing Ltd | Construction | 2014 |
| EJS Engineering Consultants Ltd | Professional & scientific | 2013 |
| Elaine Frances Clinical Aesthetics Limited | Other services | 2012 |
| Elastomeric Roofing Products Limited | Construction | 1985 |
| Electrawave Compliance Ltd | Professional & scientific | 2026 |
| Electric Lamp Company Ltd | Construction | 1998 |
| Electrical Renewable Solutions Ltd | Construction | 2026 |
| Electricwise North West Ltd | Manufacturing | 2026 |
| Electrisafe Ltd | Construction | 2025 |
| Electrotech Electrical Services Limited | Construction | 2019 |
| Elemento Ltd | Health & social care | 2023 |
| Elements NW Ltd | Construction | 2025 |
| Elftastic Ltd | Arts & recreation | 2024 |
| Eligio Health Ltd | Health & social care | 2024 |
| Eliom Limited | Health & social care | 2013 |
| Eliot Rigby Solutions Limited | Information & communication | 2019 |
| Elipsa Education Ltd | Education | 2024 |
| Elite Event Group Limited | Hospitality | 2018 |
| Elite Marquees Ltd | Administrative & support | 2013 |
| Elite Pups Ltd | Other services | 2023 |
| Elite Valet Limited | Extraterritorial | 2008 |
| Elixir Skin Clinic Ltd | Health & social care | 2018 |
| Elizabeth Court (Flat Management) Company Limited | Households | 2003 |
| ELK Enterprise Ltd | Education | 2023 |
| Ellders Property Co. Limited | Professional & scientific | 1994 |
| Ellie Jelly Ltd | Other services | 2024 |
| Ellie@Primarycareservices Ltd | Health & social care | 2015 |
| Ellington Caravan Parks Limited | Hospitality | 2005 |
| Elllf Limited | Transport & logistics | 2024 |
| ELM Lodge Flat Management Company Limited | Households | 1975 |
| ELM Sun Limited | Construction | 2004 |