| CUBIC9 LLP | | 2010 |
| Cullen & Foley Estates Ltd | Real estate | 2018 |
| Cullen & Foley Property Ltd | Construction | 2021 |
| Cumbria Comms Ltd | Professional & scientific | 2023 |
| Curdan Plant Limited | Wholesale & retail | 2011 |
| Curlett Jones Estates Limited | Real estate | 2020 |
| Curry House (Hillside) Ltd | Hospitality | 2019 |
| Curry House (NW) Limited | Hospitality | 2007 |
| Curry HUT Southport Ltd | Hospitality | 2023 |
| Curryhouse Southport Ltd | Hospitality | 2025 |
| Custodian Guarding Company Limited | Administrative & support | 2010 |
| Cuws Ltd | Wholesale & retail | 2026 |
| CVP NW Ltd | Wholesale & retail | 2024 |
| Cyberon Systems Limited | Extraterritorial | 2001 |
| Cyberthy Ltd | Information & communication | 2022 |
| Cyril Webb & Co.Limited | Construction | 1959 |
| CZ NW Consulting Ltd | Professional & scientific | 2025 |
| D & E Bennison Ltd | Professional & scientific | 2019 |
| D Archer Ltd | Education | 2021 |
| D Balmer Developments Ltd | Real estate | 2020 |
| D Evans Heating & Plumbing Ltd | Construction | 2014 |
| D F S Motor Company Limited | Transport & logistics | 2008 |
| D Grist Close Protection Services Ltd | Administrative & support | 2020 |
| D Maguire Painting & Decorating Contractors Limited | Construction | 2002 |
| D Mitchell Enterprise Ltd | Wholesale & retail | 2024 |
| D P Murphy Electrical Limited | Manufacturing | 2014 |
| D Resi One Ltd | Construction | 2025 |
| D Rimmer Consultancy & Training Ltd | Professional & scientific | 2023 |
| D S Entertainment Limited | Arts & recreation | 2017 |
| D V E Services Limited | Real estate | 2018 |
| D&D Timperley LLP | | 2025 |
| D&K Fryery Limited | Hospitality | 2022 |
| D&N Furniture and Removals Ltd | Wholesale & retail | 2019 |
| D'Vine Catering Limited | Hospitality | 2016 |
| D.A.C. Fire Protection & Insulation Limited | Construction | 2016 |
| D.B.D. Engineering Services Ltd | Professional & scientific | 2011 |
| D.F Driving Services Ltd | Transport & logistics | 2025 |
| D.Marvan Tree and Landscape Services Ltd | Administrative & support | 2016 |
| D8 Property Solutions Ltd | Real estate | 2024 |
| Daily Dose Southport Ltd | Hospitality | 2018 |
| Daily Fish Supplies Limited | Extraterritorial | 1986 |
| Dajt Ltd | Households | 2018 |
| Dalebend Limited | | 1986 |
| Dalemain House Residential Home Ltd | Health & social care | 2015 |
| Daler Construction Limited | Construction | 2004 |
| Dalestone (NW) Limited | Manufacturing | 2014 |
| Dalsan Ltd | Wholesale & retail | 2014 |
| Daltec (UK) Limited | Professional & scientific | 1982 |
| Damian LEE Coates Engineering Ltd | Professional & scientific | 2026 |
| DAN Birtwistle Ltd | Construction | 2025 |
| DAN Briscoe Consulting Ltd | Professional & scientific | 2025 |
| DAN Invest Ltd | Professional & scientific | 2020 |
| Dandelion Days EFL Ltd | Health & social care | 2022 |
| Danescourt Property Company Limited | Households | 1979 |
| Danher & Co Ltd | Professional & scientific | 2025 |
| Daniel Chippy Limited | Hospitality | 2024 |
| Darean Solutions Ltd | Construction | 2019 |
| Dark Heating Ltd | Construction | 2025 |
| Darshans Solutions PVT Limited | Information & communication | 2014 |
| Dartequal Limited | Real estate | 1986 |
| Darwen Kitchens Ltd | Hospitality | 2022 |
| Darya Southport Ltd | Wholesale & retail | 2025 |
| Dasilva Enterprise Limited | Hospitality | 2017 |
| DAT Transport Services Limited | Transport & logistics | 2021 |
| Davenport C Holdings Ltd | Real estate | 2025 |
| Daves Kochmac Limited | Wholesale & retail | 2020 |
| David Davies Estate Agent Limited | Real estate | 2000 |
| David G Properties Ltd | Real estate | 2024 |
| David Garmory 10D Ltd | Health & social care | 2024 |
| David H Myers Cleveleys Ltd | Wholesale & retail | 2021 |
| David Halsall Sons & Daughter Removals Ltd | Transport & logistics | 2008 |
| David Kearns OIL & GAS Contractor Ltd | Administrative & support | 2016 |
| David Machell Architecture Ltd | Professional & scientific | 2020 |
| David Roberts & Partners (Employee Benefits) Ltd | Financial services | 2019 |
| David Roberts & Partners (Insurance Brokers) Limited | Financial services | 1977 |
| David Roberts & Partners (York) Ltd | Financial services | 2019 |
| David Roberts & Partners Wealth Management LLP | | 2012 |
| David Roberts Technical Engineering 10040 Limited | Manufacturing | 2023 |
| David Rowell Holdings Ltd | Real estate | 2019 |
| David Rowell Ltd. | Construction | 1998 |
| David Search (Jewellers) Ltd | Wholesale & retail | 2003 |
| David Wood Business Services Limited | Professional & scientific | 2012 |
| Davidson Property Group Ltd | Real estate | 2015 |
| Davidson Property Management Ltd | Construction | 2017 |
| Davidsons (Holding Co.) Ltd | Households | 2015 |
| Davidsons (Manchester) Limited | Real estate | 1940 |
| Davies Brothers Builders Limited | Construction | 2013 |
| Davis Childcare Limited | Health & social care | 2026 |
| Davop Ltd | Transport & logistics | 2026 |
| DAW Medical Limited | Health & social care | 2022 |
| Dawid Transport Ltd | Transport & logistics | 2014 |
| Day and Night TV and Film Productions Limited | Information & communication | 2019 |
| Dayco Developments Ltd | Manufacturing | 2014 |
| Daze Detailing Ltd | Wholesale & retail | 2024 |
| DBA School of Dance Ltd | Education | 2019 |
| Dbhi Limited | Professional & scientific | 2008 |
| DC Financial Services Limited | Financial services | 2016 |
| DC Property Hub Limited | Real estate | 2019 |
| DC Target Solutions Ltd | Information & communication | 2022 |
| DCL (Southport) RTM Company Limited | Households | 2015 |