| Dice & Dumplings Restaurant Limited | Hospitality | 2025 |
| Dice and Dumplings Cards Limited | Wholesale & retail | 2024 |
| Dice and Dumplings Limited | Wholesale & retail | 2023 |
| Dice Entertainment Group Ltd | Arts & recreation | 2026 |
| Dickson Prop Co Ltd | Financial services | 2026 |
| Dickson's Wood Management Company Limited | Households | 2019 |
| Dida Autos Ltd | Wholesale & retail | 2025 |
| Dida Motor Holdings Limited | Wholesale & retail | 2024 |
| Didakta Ltd | Education | 2022 |
| Diddy Dogs Lodge Limited | Other services | 2019 |
| Dido 89 Ltd | Hospitality | 2020 |
| Diegos Ltd | Hospitality | 2013 |
| Diem Nutrition Ltd | Health & social care | 2025 |
| Diesel Vans Limited | Wholesale & retail | 2011 |
| Different Shades of Limited | Wholesale & retail | 2021 |
| Digable Marketing Ltd | Professional & scientific | 2022 |
| Digenzo Ltd | Information & communication | 2024 |
| Digi Checkout Ltd | Financial services | 2025 |
| Digi Magnetix Ltd | Information & communication | 2025 |
| Digi Small Digital Limited | Professional & scientific | 2025 |
| Digiorgio Properties Ltd | Real estate | 2025 |
| Digiserv Ltd | Other services | 2005 |
| Digital Bytes Limited | Information & communication | 2019 |
| Digital Care Assistant Limited | Information & communication | 2015 |
| Digital Green Solutions Limited | Information & communication | 2012 |
| Digital in Operations Limited | Information & communication | 2025 |
| Digital Infrastructure Consultants Ltd | Information & communication | 2026 |
| Digital Krikits Ltd | Information & communication | 2016 |
| Digital Mapping Systems Ltd | Professional & scientific | 2024 |
| Digital Nomad Consulting Ltd | Information & communication | 2022 |
| Digital One Hour Photo LAB Limited | Information & communication | 2004 |
| Digital Remote Automation Motion Limited | Administrative & support | 2013 |
| Digital Terrain Surveys (UK) Limited | Professional & scientific | 2004 |
| Digital Terrain Surveys LLP | | 2008 |
| Digital Voyager Ltd | Extraterritorial | 2020 |
| Digital Wave Group Limited | Professional & scientific | 2023 |
| Digitalbux Software Limited | Information & communication | 2023 |
| Digitalmarketingmac Ltd | Information & communication | 2024 |
| Digitalshere Limited | Professional & scientific | 2016 |
| Digitalup Ltd | Information & communication | 2017 |
| Digitech Arts Studios Ltd | Information & communication | 2025 |
| Digitek Computers Ltd | Manufacturing | 2019 |
| Digivilla Ltd | Wholesale & retail | 2020 |
| Dijets Inc Limited | Information & communication | 2023 |
| Dilan Construction Limited | Construction | 2016 |
| Dilightful Ltd | Manufacturing | 2025 |
| Diljit Ltd | Construction | 2025 |
| Dillinger Developments Limited | Construction | 2018 |
| Dilstar Limited | Construction | 2010 |
| Dimension (Watford) Management Company Limited | Households | 2004 |
| Dimension Services Ltd | Administrative & support | 2024 |
| Ding Tea UK Ltd | Hospitality | 2019 |
| Dinghy Parts Limited | Wholesale & retail | 2021 |
| Dinky Dogz Ltd | Agriculture & fishing | 2025 |
| Diono UK Limited | Administrative & support | 2001 |
| Dippydappy Ltd | Information & communication | 2025 |
| Dipto Consultancy Ltd | Information & communication | 2014 |
| Direct Carpentry Services Ltd | Construction | 2019 |
| Direct Carpets (Southampton) Ltd | Wholesale & retail | 2003 |
| Direct Carpets Hampshire Limited | Wholesale & retail | 2023 |
| Direct Carpets Hythe Ltd | Wholesale & retail | 2023 |
| Direct Cleaning (Fair Oak) Limited | Administrative & support | 2013 |
| Direct Cleaning Holdings Ltd | Financial services | 2023 |
| Direct Contract Services Ltd | Other services | 2023 |
| Direct Defence Krav Maga Ltd | Arts & recreation | 2016 |
| Direct Forwarding Ltd | Transport & logistics | 2025 |
| Direct Janitorial Supplies Limited | Other services | 1998 |
| Direct Tool Company Limited | Wholesale & retail | 2008 |
| Direct Windows & Doors Limited | Manufacturing | 2016 |
| Direction Property Limited | Real estate | 2021 |
| DIRECTION42 Ltd | Professional & scientific | 2018 |
| Directional Systems Limited | Information & communication | 2018 |
| Directional Systems Tracking Limited | Information & communication | 2018 |
| DIRICH4 Limited | Information & communication | 2018 |
| Dirt Breaker Ltd | Administrative & support | 2022 |
| Dirty Blonde Hair Salon Limited | Other services | 2023 |
| Dirty Bomb Films Ltd | Arts & recreation | 2002 |
| Disability Advice Independence Support CIC | Health & social care | 2017 |
| Disbudak Plumber and Piping Ltd | Manufacturing | 2020 |
| Discordant Films Limited | Information & communication | 2015 |
| Discount MG Rover Spares Limited | Wholesale & retail | 2019 |
| Discover Develop DO Ltd | Administrative & support | 2022 |
| Discover South Devon Limited | Professional & scientific | 2020 |
| Discover Wellness Limited | Health & social care | 2018 |
| Discovery Nurseries Ltd | Health & social care | 2021 |
| Discovery Nursery and Preschool Ltd | Education | 2015 |
| Discovery Solutions Management Ltd | Hospitality | 2020 |
| Dishuck Ltd | Real estate | 2011 |
| Dispo-Chem (UK) Limited | Wholesale & retail | 2010 |
| Disrupt Africa Ltd | Information & communication | 2016 |
| Disti Limited | Administrative & support | 2024 |
| Distinctive Art Distribution Ltd | Arts & recreation | 2024 |
| Distinctive Design Limited | Wholesale & retail | 2010 |
| Ditigalmglobal Ltd | Wholesale & retail | 2026 |
| Divas Plants Ltd | Wholesale & retail | 2023 |
| Divergent Festivals Ltd | Arts & recreation | 2022 |
| Divergent Logistics Limited | Transport & logistics | 2014 |
| Divergent Promotions Ltd | Arts & recreation | 2021 |
| Divergent Venues Ltd | Arts & recreation | 2022 |
| Divergent Yachting Limited | Professional & scientific | 2016 |