| Degenuk Ltd | Wholesale & retail | 2024 |
| Degrouchy Lane Management Company Limited | Households | 1995 |
| Deham Ltd | Construction | 2025 |
| Dehari Construction Ltd | Construction | 2024 |
| DEK Property Limited | Real estate | 2023 |
| Dekali Automotive Services Ltd | Professional & scientific | 2015 |
| Dekozaa Ltd | Other services | 2025 |
| Dekra Automotive Limited | Professional & scientific | 1996 |
| Dekra Certification UK Limited | Professional & scientific | 2021 |
| Dekra Claims International-Uk Limited | Financial services | 1966 |
| Dekra UK Ltd | Professional & scientific | 1986 |
| Dekra UK Management Ltd | Professional & scientific | 1999 |
| Delalu Delala Ltd | Information & communication | 2026 |
| Delamode International Logistics Limited | Transport & logistics | 1991 |
| Delaney Housing Ltd | Other services | 2013 |
| Delaney Park Homes Ltd | Other services | 2019 |
| Delbury Limited | Construction | 1973 |
| Delicacies Chef Ltd | Hospitality | 2021 |
| Delight Cafe Limited | Hospitality | 2015 |
| Delightsome Foods Ltd | Wholesale & retail | 2024 |
| Dell CON Ltd | Transport & logistics | 2022 |
| Dell Developments Limited | Real estate | 2005 |
| Dellemma Limited | Manufacturing | 2016 |
| Dellside Services Limited | Administrative & support | 2026 |
| Deloy Consulting Ltd | Administrative & support | 2023 |
| Delright Limited | Information & communication | 2024 |
| Delta Carpentry Ltd | Construction | 2011 |
| Delta Kinetic Ltd | Manufacturing | 2016 |
| Delta Trees Ltd | Agriculture & fishing | 2022 |
| Deltair Aerospace Limited | Manufacturing | 2002 |
| Deltasprint Limited | Information & communication | 2017 |
| Deltastring Ltd | Information & communication | 2023 |
| Deltion Limited | Information & communication | 2001 |
| Deltra(Uk) Limited | Real estate | 2019 |
| Deluxe ENT. Ltd | Hospitality | 2024 |
| Deluxe Entertainment Group Ltd | Hospitality | 2023 |
| Deluxe Scaffolding Services Limited | Construction | 2024 |
| Delvecatch Limited | Households | 1991 |
| DEM Consultants Ltd | Financial services | 2018 |
| Demiurgic Consulting Engineers Limited | Professional & scientific | 2023 |
| Demosky Ltd | Hospitality | 2026 |
| Demstar Limited | Manufacturing | 2024 |
| Dena Studio Ltd | Administrative & support | 2024 |
| Denbert Associates (Fareham) Limited | Professional & scientific | 2008 |
| Denham Recruitment Limited | Administrative & support | 2025 |
| Denis O'Neill Investments Ltd | Financial services | 2017 |
| Denis Transport Ltd | Transport & logistics | 2024 |
| Deniz Golden Scissors Ltd | Other services | 2024 |
| Dennis Hampton Lift Subcontractor Limited | Administrative & support | 2003 |
| Dennison Court Management Company (Southampton) Limited | Households | 2010 |
| Dennywood Venture Ltd | Real estate | 2018 |
| Denovo Systems Limited | Information & communication | 1998 |
| Dens, Nests, Roosts and Warrens Ltd | Real estate | 2025 |
| Densell Limited | Administrative & support | 2013 |
| Dentaid Limited | Manufacturing | 1998 |
| Dental Health Solutions Limited | Health & social care | 2017 |
| Dentawellness Turkey Ltd | Administrative & support | 2021 |
| Dentstead Brickwork Limited | Construction | 2006 |
| Denys & Oksana Letting Ltd | Information & communication | 2024 |
| Denys Expedisan Limited | Transport & logistics | 2023 |
| Denzil Properties (GS) Limited | Real estate | 2002 |
| Denzil Properties (H & S) Limited | Real estate | 2002 |
| Denzil Properties (Singh & Kaur) Limited | Real estate | 2015 |
| Denzil Property Investments Ltd | Real estate | 2026 |
| Denzo Engineering Ltd | Wholesale & retail | 2024 |
| DEO Fade Ltd | Other services | 2026 |
| DEP Kebabs Ltd | Hospitality | 2020 |
| Dependable Distribution Limited | Transport & logistics | 2018 |
| Deplan Limited | Professional & scientific | 2014 |
| Depthless Ltd | Information & communication | 2026 |
| DER Kreis UK LLP | | 2013 |
| Derek Young Electrical Limited | Construction | 2018 |
| Derelict Design Ltd | Manufacturing | 2014 |
| Derive Store Ltd | Wholesale & retail | 2025 |
| Dermanurse Limited | Health & social care | 2019 |
| Dermasculpt Ltd | Health & social care | 2016 |
| Dermology Limited | Health & social care | 2018 |
| Dern Travel Limited | Administrative & support | 2025 |
| Derrick & Sons Property Investors SPV 1 Ltd | Real estate | 2017 |
| Derry Owen Architects Ltd | Professional & scientific | 2014 |
| DES RES Cars Limited | Wholesale & retail | 2019 |
| Des'N'Trace Limited | Wholesale & retail | 2008 |
| Desertco Limited | Hospitality | 2025 |
| Design Burst Limited | Extraterritorial | 2010 |
| Design Collaborative Ltd | Professional & scientific | 2014 |
| Design DEC Ltd | Construction | 2023 |
| Design House (Holdings) Limited | Financial services | 2013 |
| Design Maison Ltd | Wholesale & retail | 2022 |
| Design Pulse Ltd | Arts & recreation | 2024 |
| Design Some Moore Ltd | Professional & scientific | 2022 |
| Design Support and Solutions Limited | Professional & scientific | 2009 |
| Designate Limited | Manufacturing | 1978 |
| Designated Couriers Ltd | Transport & logistics | 2016 |
| Designed by Grace Ltd | Wholesale & retail | 2023 |
| Designer Aviation Limited | Manufacturing | 1997 |
| Designess Cost Consultancy Ltd | Administrative & support | 2024 |
| Designess Ltd | Arts & recreation | 2016 |
| Designing and Building Limited | Construction | 2026 |
| Desired Results Limited | Administrative & support | 2011 |
| Despa Transport Ltd | Transport & logistics | 2014 |