| Refine and Dine Limited | Hospitality | 2025 |
| Refine BW Limited | Other services | 2025 |
| Refine Fareham Limited | Other services | 2024 |
| Refine ME Ltd | Other services | 2016 |
| Refine Southern Limited | Other services | 2023 |
| Refine Training Limited | Other services | 2024 |
| Refit International Ltd | Manufacturing | 2020 |
| Reflect (Forum) Ltd | Real estate | 2021 |
| Reflect Canal House Ltd | Construction | 2020 |
| Reflect Construction Ltd | Construction | 2019 |
| Reflect Group Ltd | Professional & scientific | 2021 |
| Reflect Homes 1 Limited | Construction | 2026 |
| Reflect Homes Limited | Construction | 2012 |
| Reflect Real Estate Ltd | Construction | 2026 |
| Reflect Rentals Ltd | Real estate | 2019 |
| Reflected Media Ltd. | Information & communication | 2004 |
| Reflections Environmental Ltd. | Administrative & support | 2012 |
| Reflections Merchandise Ltd | Wholesale & retail | 2018 |
| Reframe Support Ltd | Health & social care | 2026 |
| REG Tuftyslugs Limited | Construction | 2012 |
| Regal Autosport (International) Limited | Wholesale & retail | 1999 |
| Regal Autosport Holdings Limited | Financial services | 2021 |
| Regal Care Solutions Limited | Health & social care | 2022 |
| Regal Environmental Systems Limited | Manufacturing | 1995 |
| Regal Lashes Ltd | Wholesale & retail | 2024 |
| Regal Letting Agency Limited | Real estate | 2023 |
| Regal Mice Ltd | Administrative & support | 2025 |
| Regal Roofcare Ltd | Construction | 2026 |
| Regalis Automata Ltd | Wholesale & retail | 2024 |
| Regans @ the New Inn Limited | Other services | 2018 |
| Regency Auctions Ltd | Professional & scientific | 2025 |
| Regency Homes (Southampton) Limited | Households | 1988 |
| Regency Hospitality Limited | Hospitality | 2026 |
| Regency Place (Leatherhead) Management Company Limited | Households | 2011 |
| Regents Court (Southampton) Management Company Limited | Households | 2002 |
| Regents Electrical Ltd | Construction | 2020 |
| Regents Park Electrical Ltd | Extraterritorial | 2022 |
| Regents Park Mobile Automotive Ltd | Wholesale & retail | 2022 |
| Regents Property Agents Limited | Construction | 1987 |
| Regents Property Limited | Real estate | 2016 |
| Regginas Restaurant Limited | Hospitality | 2000 |
| Reginnas Holdings Limited | Financial services | 2020 |
| Regional Express Limited | Transport & logistics | 2012 |
| Regis Bentley Limited | Financial services | 2013 |
| REGIT4U Ltd | Information & communication | 2020 |
| Regsiv & AO UK Ltd | Wholesale & retail | 2018 |
| Rehman Groups & Ltd | Wholesale & retail | 2025 |
| Rehman Holdings INT Ltd | Wholesale & retail | 2026 |
| Rehmankitchens Ltd | Hospitality | 2026 |
| Rehoboth City Homes Ltd | Real estate | 2025 |
| Rehoboth Cleaning Services Ltd | Administrative & support | 2022 |
| Rehoboth Group of Company Ltd | Administrative & support | 2022 |
| Reichenheim & Daughters Ltd | Administrative & support | 2026 |
| Reid Banks Ltd | Construction | 2019 |
| Reignite Yoga Ltd | Arts & recreation | 2024 |
| Reilly Construction Limited | Construction | 1987 |
| Reilly Developments Limited | Construction | 1998 |
| Reinforcement of Timber Structures Limited | Construction | 2004 |
| Reino Finance Group Limited | Administrative & support | 2023 |
| Rejo Health Care Limited | Health & social care | 2020 |
| Rejuved Ltd | Other services | 2021 |
| Rejuvenate Aesthetics Clinic Ltd | Health & social care | 2020 |
| Rejuvenesce Ltd | Other services | 2014 |
| Rekan Group Limited | Financial services | 2019 |
| Rekkruut Ltd | Other services | 2021 |
| Relax & Enjoy Ltd | Construction | 2017 |
| Relay Fire Safety Ltd | Construction | 2022 |
| Relebohile Ltd | Health & social care | 2013 |
| Reli Ltd | Professional & scientific | 2020 |
| Reliab CAB Ltd. | Transport & logistics | 2025 |
| Reliab Ltd. | Financial services | 2025 |
| Reliab Taxis Ltd. | Transport & logistics | 2025 |
| Reliable Infotech Limited | Information & communication | 2015 |
| Reliance Concrete Solution Ltd | Construction | 2017 |
| Reliance Employment Limited | Administrative & support | 1993 |
| Religioscapes CIC | Professional & scientific | 2023 |
| Reload Games Ltd | Administrative & support | 2021 |
| Remarkplus Limited | Manufacturing | 2024 |
| Remidi Limited | Professional & scientific | 2012 |
| Remote Elite Ltd | Administrative & support | 2025 |
| Remotrans Limited | Transport & logistics | 2025 |
| Remy Electrics Limited | Construction | 2006 |
| REN Expert Ltd | Professional & scientific | 2025 |
| REN Think Ltd | Professional & scientific | 2025 |
| Renaissance Corporate Group Ltd | Manufacturing | 2024 |
| Renata Property Ltd | Real estate | 2026 |
| Renaud Luxury Crafts Limited | Wholesale & retail | 2022 |
| Renders World Ltd | Construction | 2016 |
| Renderwall Ltd | Construction | 2023 |
| Renewable Energy 4 U Ltd | Construction | 2023 |
| Renewable Energy Installs Limited | Other services | 2018 |
| Renewable Generation Limited | Professional & scientific | 2021 |
| Renewable Solution Group Limited | Energy | 2024 |
| Renewal Integrative Rehab Ltd | Health & social care | 2025 |
| Renewal MS22 Ltd | Health & social care | 2025 |
| Renewed Minds Limited | Health & social care | 2024 |
| Renji Thomas Ltd | Health & social care | 2015 |
| Renlo Recruitment Ltd | Administrative & support | 2023 |
| RENOV8 Carpentry & Building Ltd | Manufacturing | 2023 |
| Renova Clinic Limited | Health & social care | 2016 |