| CB Wellness Limited | Arts & recreation | 2024 |
| Cb&Gb Ltd | Hospitality | 2025 |
| CCS Training and Consultancy Ltd | Professional & scientific | 2024 |
| Ccsb Property Ltd | Real estate | 2023 |
| Cell Pack Solutions Limited | Manufacturing | 2001 |
| Centaurea Homes Limited | Real estate | 2017 |
| Central Exchange Buildings Newcastle Management Limited | Households | 2001 |
| Central Heating and Plumbing Ltd | Construction | 2017 |
| Ceps Projects Ltd | Construction | 2023 |
| Cerat Limited | Construction | 2014 |
| CHA Cha's & Co Limited | Hospitality | 2013 |
| Championi Emergency Plumbing Limited | Other services | 2023 |
| Chapel House South Shields Management Limited | Real estate | 2007 |
| Chapman and Gosling Limited | Construction | 2021 |
| Charcait Limited | Administrative & support | 2019 |
| Charlestons Coffee Shop Limited | Hospitality | 2015 |
| Charm Hair and Beauty Ltd | Other services | 2021 |
| Charming Chic Ltd | Wholesale & retail | 2025 |
| Charnwood Court 2018 Ltd | Households | 2018 |
| Checkmate Entertainment Studio Ltd | Arts & recreation | 2024 |
| Cheetham Property Services Ltd | Real estate | 2023 |
| Chef Elliott Ltd | Hospitality | 2024 |
| Cheftech Ltd | Hospitality | 2026 |
| Chellos North East Ltd | Wholesale & retail | 2013 |
| Chez Frites (NE) Limited | Hospitality | 2026 |
| CHI RHO Ltd | Real estate | 2024 |
| Chichester Express Ltd | Wholesale & retail | 2026 |
| Chichester News Ltd | Wholesale & retail | 2025 |
| Chichester Shields Ltd | Wholesale & retail | 2026 |
| Chloe Events Ltd | Hospitality | 2024 |
| Chokar & Co Ltd | Professional & scientific | 2020 |
| Choudhury Properties (NO.2) Limited | Real estate | 2008 |
| Chris MAY CS Ltd | Other services | 2016 |
| Christopher D Miller Ltd | Professional & scientific | 2019 |
| Christopher Quinn Logistics Ltd | Transport & logistics | 2025 |
| Chubby Couriers Ltd | Transport & logistics | 2025 |
| Church View (South Hylton) Property Management Company Limited | Real estate | 2007 |
| Civilized Poison Limited | Hospitality | 2015 |
| CJ Counselling and Well-Being Ltd | Health & social care | 2023 |
| CJC Food Supplies Ltd | Wholesale & retail | 2024 |
| CK Lift Services Ltd | Professional & scientific | 2025 |
| CK Roses Wonderland CIC | Health & social care | 2023 |
| Clamos Carpet Cleaning NE Ltd | Administrative & support | 2025 |
| Clan Ltd | Wholesale & retail | 2026 |
| Classhouse Consulting Services Limited | Professional & scientific | 2018 |
| Classhouse Holdings Limited | Financial services | 2016 |
| Classhouse Property Limited | Real estate | 2012 |
| Claxby Electrical Services Ltd | Construction | 2026 |
| CLC Enterprise Limited | Professional & scientific | 2013 |
| Cleadon Manor Apartments Phase 10 Management Company Limited | Real estate | 2016 |
| Cleadon Old Hall Management Company Limited | Households | 1966 |
| Cleadon Park Management Company Limited | Households | 1982 |
| Cleadon Vale (Two) Management Company Limited | Households | 2012 |
| Cleadon Vale Management Company Limited | Households | 2008 |
| Clean Slate Emporium Ltd | Wholesale & retail | 2021 |
| Cleaner at South Ltd | Administrative & support | 2024 |
| Cleanwatts Ltd | Information & communication | 2019 |
| Clearview Maintenance (N.E) Limited | Other services | 2018 |
| Clinton's Contractor's Ltd | Administrative & support | 2017 |
| Clockwork Orange Ltd | Energy | 2025 |
| Cloudgenisys Ltd | Professional & scientific | 2024 |
| CMC Digital Limited | Other services | 2006 |
| CMD FM Services Limited | Construction | 2024 |
| CMF Creative Ltd | Professional & scientific | 2021 |
| Coastal Campers Conversion Limited | Wholesale & retail | 2024 |
| Coastline Commercial Ltd | Wholesale & retail | 2025 |
| Coastline Property Service Ltd | Real estate | 2025 |
| Coble Consulting Ltd | Professional & scientific | 2025 |
| Cobra North East Ltd | Administrative & support | 2020 |
| COG Renovations Limited | Construction | 2022 |
| Cold Fusion Technology Ltd | Wholesale & retail | 2026 |
| Colin Lilley Management Limited | Real estate | 2000 |
| Collins FM Services Ltd | Construction | 2022 |
| Colmans Newcastle Limited | Hospitality | 2025 |
| Colmans Seafood Temple Limited | Hospitality | 2017 |
| Colmans South Shields Limited | Hospitality | 2025 |
| Colmans Whitburn Limited | Hospitality | 2026 |
| Community Media School CIC | Information & communication | 2025 |
| Compac Services (NE) Limited | Construction | 1988 |
| Compact for Race Equality in South Tyneside Limited | Health & social care | 2016 |
| Compass Construction NE Ltd | Construction | 2018 |
| Complete Ballet CIC | Education | 2023 |
| Complete Composites Limited | Construction | 2006 |
| Compria Ltd | Professional & scientific | 2025 |
| Compteq IT Solutions Ltd | Information & communication | 2024 |
| Confidence Catalyst Community Interest Company | Professional & scientific | 2025 |
| Connected Careers and Skills UK Ltd | Information & communication | 2025 |
| Connected Families CIC | Health & social care | 2024 |
| Conversiontech Ltd | Transport & logistics | 2025 |
| Convia Property Limited | Real estate | 2025 |
| Cook & Dawson (Engineers & Engravers) Limited | | 1965 |
| Cooperdog Ltd | Real estate | 2002 |
| Copperbright Limited | Extraterritorial | 2011 |
| Cornerstone Technical Ltd | Other services | 2021 |
| Corporate Funfairs Limited | Arts & recreation | 2006 |
| Corporation Quay Management Company Limited | Households | 1995 |
| Corsetry and Couture Ltd | Manufacturing | 2009 |
| Cosmedic AF Limited | Health & social care | 2021 |
| Cottage Gardens Freehold Ltd | Real estate | 2017 |
| Covee Ltd | Administrative & support | 2025 |