| Springtime Consultants Limited | Administrative & support | 2003 |
| Springwise Limited | Construction | 1985 |
| Sprydon Designs Ltd | Real estate | 2008 |
| Square Foot Concepts Ltd | Transport & logistics | 2006 |
| Squires Development Limited | Construction | 2001 |
| SRT Security Systems Limited | Professional & scientific | 2000 |
| ST Davids Poultry Team Limited | Professional & scientific | 2006 |
| Stafford & Coomber Limited | Construction | 2004 |
| Stanley Family Property Ltd | Real estate | 2023 |
| Stansell Farms Limited | Extraterritorial | 2006 |
| Staple Farm Developments Limited | Construction | 2018 |
| Staple Farm Holdings Limited | Financial services | 2025 |
| Stats Developments Limited | Construction | 1980 |
| Steart Farms Limited | Agriculture & fishing | 2003 |
| Steden Limited | Extraterritorial | 2003 |
| Steele Sports Consulting Ltd | Education | 2015 |
| Stef Langdons Ltd | Transport & logistics | 1971 |
| Stephen Johns (South West) Limited | Wholesale & retail | 1989 |
| Steve Sparks Limited | Manufacturing | 2002 |
| Stewkley Limited | Professional & scientific | 1965 |
| Stitchlinks C.I.C. | Health & social care | 2005 |
| Stobooks Limited | Professional & scientific | 1994 |
| Stonehall Developments Limited | Construction | 2001 |
| Stonemaster Developments Limited | Construction | 2003 |
| Stotts Property Limited | Financial services | 2022 |
| Stowell Concrete Limited | Manufacturing | 1972 |
| Stowell Hill Limited | Agriculture & fishing | 1972 |
| Strategic Business Coaching Ltd | Education | 2002 |
| Street Estates Limited | Wholesale & retail | 1934 |
| Stretcholt Builders Limited | Construction | 2003 |
| Strongreach Limited | Professional & scientific | 2023 |
| STS Agri Plant Ltd | Agriculture & fishing | 2026 |
| Stuart Millin Consultancy Ltd | Information & communication | 2015 |
| Studio Prints (Frome) Limited | Wholesale & retail | 2003 |
| Styles DOT Studio Ltd | Professional & scientific | 2018 |
| Sugesan UK Ltd | Wholesale & retail | 2023 |
| Summerfield Developments (SW) Limited | Construction | 1990 |
| Summerfield Homes Ltd | Construction | 2006 |
| Summerfield Residential Lettings Limited | Real estate | 2006 |
| Summerfield South West Limited | Administrative & support | 2005 |
| Summershard Two Limited | Real estate | 2016 |
| Supernova Dent Bridgwater Limited | Health & social care | 2024 |
| Supernova Dent Holdings Limited | Financial services | 2024 |
| Supreme Food Courts Limited | Hospitality | 2003 |
| Suremime Limited | Hospitality | 1981 |
| Swift Mechanical Group Limited | Construction | 1989 |
| Sydent Limited | Health & social care | 2021 |
| Symonds Group Ltd | Real estate | 2019 |
| System Solutions Hub Ltd | Information & communication | 2019 |
| Systems Axis Limited | Information & communication | 1989 |
| Systems Axis Technologies Limited | Information & communication | 1988 |
| T & C Motor Services Limited | Wholesale & retail | 2003 |
| T Carnell Engineering Ltd | Professional & scientific | 2007 |
| T Francis Electrical Services Limited | Construction | 2003 |
| T J a Rigby Haulage Limited | Transport & logistics | 2004 |
| T P Haley Limited | Professional & scientific | 2020 |
| T S Converting Equipment Limited | Manufacturing | 2003 |
| T.Q. Exel Limited | Education | 2000 |
| Talent Direct Limited | Administrative & support | 2001 |
| Tanyard Farm Nurseries (Lower Weare) Limited | Agriculture & fishing | 1964 |
| Taunton Deane Bowling Club Limited | Arts & recreation | 1995 |
| Taunton Surfacing and Construction Co. Limited | Professional & scientific | 1981 |
| Tayco Building Products Limited | Administrative & support | 1986 |
| TCL Property Services Ltd | Wholesale & retail | 2025 |
| Tece Limited | Administrative & support | 2001 |
| Terrinet Limited | Information & communication | 1999 |
| Tfio Properties Limited | Real estate | 2002 |
| THE 2 Vane Street Bath (Management) Company Limited | Households | 1989 |
| THE Ammerdown Centre | Education | 1992 |
| THE Bradfords Group Limited | Professional & scientific | 1999 |
| THE Brainwave Centre Limited | Health & social care | 1998 |
| THE Brainwave Trading Company Limited | Wholesale & retail | 1998 |
| THE Burnham and Berrow Golf Club Trustee Company Limited | Arts & recreation | 1910 |
| THE Cheddar Gorge Cheese Company Limited | Manufacturing | 1991 |
| THE Cleve Hotel Limited | Hospitality | 2003 |
| THE Cornwall GAS Co. Limited | Construction | 1995 |
| THE Courtyard (Minehead) Residents Company Limited | Health & social care | 1988 |
| THE Devon GAS Co. Limited | Construction | 1995 |
| THE Enviroshop Limited | Administrative & support | 1993 |
| THE Fireplace Fitters Shop Ltd | Construction | 2017 |
| THE Frome Museum | Arts & recreation | 1989 |
| THE Fruit & VEG Shop | | 1994 |
| THE Gardens Entertainments Limited | Wholesale & retail | 1988 |
| THE Glastonbury Goddess Temple | Other services | 2006 |
| THE Glastonbury Press Ltd | Wholesale & retail | 2004 |
| THE Greenwood Partnership Ltd | Hospitality | 1996 |
| THE Lamyatt Management Company Limited | Households | 1992 |
| THE Meeting House Cafe Limited | Hospitality | 2004 |
| THE MIX Music Education Limited | Education | 2010 |
| THE Mount Hair Salon Limited | Other services | 2006 |
| THE Net-Work Meetings Limited | Administrative & support | 2007 |
| THE Premier Mushroom Group Limited | Agriculture & fishing | 2005 |
| THE Pretty Soapery Ltd | Manufacturing | 2021 |
| THE Real Italian Pizza Company Limited | Hospitality | 2007 |
| THE Red Lion Inn (Babcary) Limited | Hospitality | 2002 |
| THE Residual Property Company Limited | Extraterritorial | 2003 |
| THE Royal Bath & West of England Society | Health & social care | 1994 |
| THE Rubber Rigid Inflatable Boat Company Limited | Transport & logistics | 2003 |
| THE Somerset Farrier Ltd | Agriculture & fishing | 2019 |
| THE Somerset GAS Co. Limited | Construction | 1995 |