| S & S Laser Solutions Limited | Health & social care | 2011 |
| S 52 Contractors Limited | Construction | 2026 |
| S a Silks Ltd | Wholesale & retail | 2025 |
| S D Modi & Co Limited | Professional & scientific | 2010 |
| S J H Construct Limited | Construction | 2020 |
| S K D Taverns FS Ltd | Wholesale & retail | 2022 |
| S N Builder Midlands Ltd | Construction | 2025 |
| S P Sapra Ltd | Wholesale & retail | 2019 |
| S Paswal Ltd | Wholesale & retail | 2024 |
| S Paul & SON Properties Ltd | Real estate | 2017 |
| S Q Blinds Ltd | Other services | 2018 |
| S R Cuisine Ltd | Hospitality | 2025 |
| S Wahla Ltd | Construction | 2026 |
| S Y Trading ( Derby ) Ltd | Construction | 2022 |
| S&G Food Ltd | Administrative & support | 2019 |
| S&H Parmar Haulage Ltd | Transport & logistics | 2018 |
| S&S Prime Investments Ltd | Real estate | 2024 |
| S&S Recovery Ltd | Wholesale & retail | 2024 |
| S&Y Trade Ltd | Wholesale & retail | 2024 |
| S-K 1 Shop Limited | Wholesale & retail | 2025 |
| S-Lite Marketing Ltd | Construction | 2019 |
| S. Sohal Builders Limited | Construction | 2021 |
| S.A.M UK Investment Ltd | Real estate | 2024 |
| S.Y Associates Limited | Wholesale & retail | 2025 |
| S2A Ventures Limited | Wholesale & retail | 2026 |
| SA Entreprise UK Ltd | Wholesale & retail | 2025 |
| SA Records Ltd | Information & communication | 2020 |
| Saad Mart Ltd | Wholesale & retail | 2025 |
| Saafi 1.A Limited | Health & social care | 2025 |
| Sabri Groups Limited | Transport & logistics | 2022 |
| Saed Limited | Professional & scientific | 2019 |
| Safa MOT Centre Ltd | Wholesale & retail | 2026 |
| Safa Trading Ltd | Hospitality | 2025 |
| Safar Foods Ltd | Hospitality | 2023 |
| Safar Properties UK Limited | Real estate | 2018 |
| Safe Carrier Ltd | Transport & logistics | 2022 |
| Safe Have Limited | Education | 2015 |
| Safelocks Storage Limited | Transport & logistics | 2023 |
| Safety Inspection Services Limited | Manufacturing | 2026 |
| Safeway Construction (West Midlands Limited | Construction | 2018 |
| Sagar Couriers Ltd | Transport & logistics | 2023 |
| Sagar Sweets Ltd | Hospitality | 2020 |
| Sahara Homes Limited | Hospitality | 2025 |
| Sahil UK Ltd | Wholesale & retail | 2020 |
| Sahota Group Limited | Professional & scientific | 1993 |
| Sahota Interiors Ltd | Construction | 2026 |
| Saini Xpress Ltd | Transport & logistics | 2026 |
| Saints Consulting Ltd | Education | 2026 |
| Saira Investments Limited | Real estate | 2024 |
| Saiz Group Limited | Financial services | 2024 |
| Sakuma Advance Rehab (S.A.R.) Ltd | Health & social care | 2020 |
| Salar 24/7 Store Ltd | Wholesale & retail | 2026 |
| Sally Broome Limited | Information & communication | 2004 |
| Salon DÉ Beaut Ltd | Other services | 2017 |
| Saltec Ltd | Construction | 2020 |
| SAM & Chris Ltd | Wholesale & retail | 2019 |
| SAM Property WM Ltd | Real estate | 2021 |
| SAM2 Ltd | Information & communication | 2019 |
| Samaniya Ltd | Health & social care | 2020 |
| Sameday Courier U.K. Ltd | Transport & logistics | 2025 |
| Sameday Transport Limited | Transport & logistics | 2025 |
| Sami Solutions Limited | Wholesale & retail | 2013 |
| Sammi Group Ltd | Manufacturing | 2021 |
| Samra G Courier Limited | Transport & logistics | 2025 |
| Sams Authentic Limited | Wholesale & retail | 2020 |
| Sams News (SMK) Ltd | Wholesale & retail | 2022 |
| Sams Vegan Delights Ltd | Hospitality | 2024 |
| Samuel White & SON Ltd | Hospitality | 2021 |
| Sam’S AF Ltd | Wholesale & retail | 2026 |
| Sana Tyres Ltd | Wholesale & retail | 2024 |
| Sanceleste Transport Ltd | Transport & logistics | 2025 |
| Sand Box Studios Ltd | Arts & recreation | 2023 |
| Sandal & Hear Properties Ltd | Real estate | 2021 |
| Sandals Property Ltd | Real estate | 2021 |
| Sanderz Ltd | Wholesale & retail | 2013 |
| Sandford Solutions Limited | Wholesale & retail | 2023 |
| Sandhu Courier Limited | Transport & logistics | 2019 |
| Sandhu Courier Services Ltd | Transport & logistics | 2026 |
| Sandhu Food Consultants Ltd | Professional & scientific | 2018 |
| Sandhu Housing Investments Ltd | Real estate | 2025 |
| Sandhu Logistics Midlands Ltd | Transport & logistics | 2024 |
| Sandrana Building Services Ltd | Construction | 2016 |
| Sandru Fast Ltd | Transport & logistics | 2019 |
| Sandwell & Birmingham Properties Ltd | Real estate | 2017 |
| Sandwell Asian Family Support Service Limited | Health & social care | 2001 |
| Sandwell Financial Services Ltd | Financial services | 2002 |
| Sandwell Fish Bar Ltd | Hospitality | 2019 |
| Sandwell Homeless and Resettlement Project Limited | Health & social care | 1983 |
| Sandwell Lettings Limited | Real estate | 2025 |
| Sandwell Property Agency Ltd | Real estate | 2024 |
| Sandwell Property Lettings Limited | Real estate | 2011 |
| Sandwell UP CIC | Education | 2026 |
| Sandwell Welding Ltd | Manufacturing | 2009 |
| Sangha Consulting Limited | Administrative & support | 2021 |
| Sangtec Ltd | Construction | 2020 |
| Sanjh.Const Ltd | Construction | 2017 |
| Sankol Limited | Wholesale & retail | 2023 |
| Santec Ltd | Construction | 2020 |
| Sarai Properties Limited | Real estate | 2012 |
| Sartaj Creations Ltd | Construction | 2019 |