| Reefdoctor | Professional & scientific | 2005 |
| Reel to Reel International Limited | Manufacturing | 2019 |
| Reel to Reel Machinery International Limited | Professional & scientific | 1998 |
| Reelium Studio Ltd | Information & communication | 2025 |
| Reem Studios Ltd | Professional & scientific | 2022 |
| Reenergise Waste Limited | Professional & scientific | 2016 |
| REF (North) Limited | Financial services | 2025 |
| Regal Lounge Ltd | Hospitality | 2023 |
| Regent Court Management Ilkley Limited | Households | 1983 |
| Rehmans Cottage Ltd | Hospitality | 2024 |
| Reid Moffat & Co Limited | Professional & scientific | 2011 |
| Renacida Lash Ltd | Other services | 2025 |
| Repair LAB (Retail) Limited | Other services | 2018 |
| Repair LAB Leeds Limited | Manufacturing | 2015 |
| Resolve Gets Results Ltd | Other services | 2016 |
| Rethinking Health CIC | Health & social care | 2025 |
| Rethinking Wellbeing Ltd | Public administration | 2025 |
| Revenue Brain Ltd | Wholesale & retail | 2020 |
| Revive Skin Clinic Limited | Health & social care | 2025 |
| Reward Fabrications Ltd | Manufacturing | 2011 |
| RGK Gargrave Limited | Real estate | 2025 |
| RGK Holding Group Limited | Real estate | 2025 |
| RGK Real Estate Limited | Real estate | 2025 |
| RGV Consulting Limited | Professional & scientific | 2026 |
| Rhamy Ltd | Hospitality | 2023 |
| Rhba Holdings Ltd | Financial services | 2026 |
| Rhino Data Ltd | Information & communication | 2023 |
| Rhythm Time Yorkshire North West Ltd | Arts & recreation | 2021 |
| Ribble Consulting Limited | Professional & scientific | 2024 |
| Ribble Valley Glamping Limited | Hospitality | 2017 |
| Ribblesdale Court (Long Preston) Management Company Limited | Water & waste | 2020 |
| Rice- Birchall Construction Ltd | Construction | 2023 |
| Rice-Birchall Holdings Ltd | Financial services | 2023 |
| Richard Breare Consultancy Limited | Professional & scientific | 2003 |
| Richard Fattorini Limited | Other services | 2026 |
| Richard William Hall Ltd | Construction | 2016 |
| Richardson Bars Ltd | Hospitality | 2024 |
| Riddale Ltd | Construction | 2009 |
| Ridding Construction Ltd | Construction | 2019 |
| Right Surveyors Yorkshire Limited | Professional & scientific | 2012 |
| Rigseil Limited | Mining & quarrying | 2011 |
| Ringguard Limited | Information & communication | 1999 |
| Ripple CRM Limited | Information & communication | 2018 |
| Riverbank Burnsall Limited | Hospitality | 2018 |
| Riversdale Properties Limited | Construction | 2005 |
| Riversview Properties Limited | Real estate | 2024 |
| RJ Sadler Properties Ltd | Construction | 2026 |
| RJP Consultancy Ltd | Administrative & support | 2019 |
| RJW Pharma Research Limited | Administrative & support | 2010 |
| RKB Electrical Ltd | Construction | 2013 |
| RLH Consults Ltd | Administrative & support | 2025 |
| Robert Bunney Countrywear Limited | Wholesale & retail | 2021 |
| Robert M Tyson Ltd | Manufacturing | 2025 |
| Rock & Roles Ltd | Construction | 2023 |
| Rockville Property Group Ltd | Real estate | 2025 |
| Rofer and Rodi (UK) Limited | Wholesale & retail | 2008 |
| Roger Dakin & Sons Limited | Agriculture & fishing | 2017 |
| Roger Fielding Consulting Limited | Professional & scientific | 2009 |
| Rollingwood Productions Limited | Arts & recreation | 2016 |
| Rookfd Ltd | Professional & scientific | 2012 |
| Rosandell Limited | Real estate | 2008 |
| Rosina Care Services Ltd. | Health & social care | 2016 |
| Round House Podiatry Ltd | Health & social care | 2019 |
| Rowland Street Stores Ltd | Wholesale & retail | 2013 |
| Royley Development Company Ltd. | Construction | 2004 |
| Rozies Curry House Ltd | Hospitality | 2022 |
| Rpdjoinery Ltd | Construction | 2020 |
| RU Foods Express Ltd | Hospitality | 2024 |
| Runright Ltd | Health & social care | 2017 |
| Rural Business Centres Limited | Construction | 1987 |
| Rural Concepts (Libya) Limited | Extraterritorial | 2015 |
| Rural Concepts Construction Limited | Construction | 1998 |
| Rural Concepts Investments Limited | Construction | 2014 |
| Rural Concepts Limited | Administrative & support | 2003 |
| Russell Baker Consultancy Services Ltd | Professional & scientific | 2015 |
| Rvfn Limited | Information & communication | 2018 |
| RWS Builders Limited | Construction | 2016 |
| Ryan Binner Plumbing & Heating Limited | Construction | 2024 |
| Rylo Freight Services Limited | Transport & logistics | 1981 |
| S & H Kitchens and Joinery Limited | Manufacturing | 2017 |
| S & H Properties & Lettings Limited | Real estate | 2025 |
| S & J Distribution Limited | Wholesale & retail | 2006 |
| S & J Polythene and Paper Limited | Extraterritorial | 2017 |
| S J Hardaker Limited | Agriculture & fishing | 2003 |
| S J Robinson Ltd | Construction | 2022 |
| S Khan Investments Holdings Ltd | Real estate | 2024 |
| S R Shuttleworth Ltd | Agriculture & fishing | 2022 |
| S.A Micropub Skipton Limited | Hospitality | 2020 |
| Sacred Heart Alchemy Limited | Health & social care | 2017 |
| Sadler Properties (Boroughbridge) Limited | Real estate | 2021 |
| Sagraphics Ltd | Information & communication | 2009 |
| Sales BEE Ltd | Professional & scientific | 2022 |
| Saljon Properties Limited | Real estate | 2012 |
| Salpo Ltd | Hospitality | 2019 |
| Salt Pots Ltd | Arts & recreation | 2016 |
| Sander & SON Ltd | Real estate | 2014 |
| Sandpiper & Sons Properties Limited | Real estate | 2024 |
| Sarah Lewis Consulting Limited | Professional & scientific | 2025 |
| Sassteelservices Ltd | Manufacturing | 2019 |
| Sawtooth Shelf Brackets Limited | Construction | 2026 |