| Style Coaching Limited | Education | 2015 |
| Stylecare (Hairstudio) Limited | Other services | 2003 |
| Subvert Events Limited | Arts & recreation | 2020 |
| Suckley Rednal Limited | Agriculture & fishing | 2011 |
| Sugar Crave Ltd | Wholesale & retail | 2018 |
| Sugar Rushh UK Ltd | Hospitality | 2025 |
| Suiteselect Ltd | Administrative & support | 2021 |
| Suma (Developments) Limited | Construction | 1975 |
| Suma Estates Limited | Households | 2018 |
| Suma KPS Limited | Construction | 2024 |
| Suma Property Limited | Professional & scientific | 2022 |
| Sumanthara Ltd | Health & social care | 2022 |
| Summerfield Childcare Ltd | Health & social care | 2015 |
| Summerfield Court Limited | Households | 1987 |
| Summerhouse Solutions Limited | Wholesale & retail | 2014 |
| Summitlogic Consulting Ltd | Information & communication | 2025 |
| Summitqwest Ground Limited | Administrative & support | 2016 |
| Sumner & Hughes Ltd | Wholesale & retail | 2021 |
| Sumner Consultancy Ltd | Professional & scientific | 2015 |
| Sun WAH Catering Limited | Hospitality | 2019 |
| Sundorne Haulage Ltd | Transport & logistics | 2015 |
| Sundorne Nominee NO. 1 Limited | Real estate | 2025 |
| Sundorne Nominee NO. 2 Limited | Real estate | 2025 |
| Sundorne Products (Welsh Pool) Limited | Real estate | 1965 |
| Sunflower Tipis Ltd | Administrative & support | 2022 |
| Sunnyside Farm Caravan Park & Fishery Ltd | Agriculture & fishing | 2012 |
| Sunset Taverns Ltd | Hospitality | 2009 |
| Super Business Goose Limited | Financial services | 2021 |
| Superb Events Limited | Administrative & support | 2022 |
| Supertune Limited | Agriculture & fishing | 2006 |
| Superwide Investments Limited | Manufacturing | 2023 |
| Superwide Limited | Manufacturing | 2012 |
| Supported Accommodation and Independant Living Ltd | Health & social care | 2010 |
| Sure Digital Limited | Information & communication | 2020 |
| Surebuild Contracting Limited | Construction | 2025 |
| Surecare Shropshire Limited | Health & social care | 2003 |
| Surf Group Ltd | Information & communication | 2016 |
| Surgi-Derm Ltd | Health & social care | 2019 |
| Survey 2 Design Limited | Professional & scientific | 2010 |
| Survey Logic Limited | Professional & scientific | 2020 |
| Sutherland Cars Limited | Wholesale & retail | 2024 |
| Sutherland Close Flats (Romsey) Limited | Households | 1976 |
| Sutton and SON (St.Helens) Limited | Transport & logistics | 1954 |
| Sutton Farm Butchers Ltd | Wholesale & retail | 2017 |
| Sutton Park (Wisbech) Management Company Limited | Real estate | 2022 |
| Suttons Transport Group Limited | Professional & scientific | 1996 |
| SV Meat Limited | Wholesale & retail | 2024 |
| SV Pet Food Limited | Manufacturing | 2024 |
| Sven Kili Consulting Ltd | Professional & scientific | 2014 |
| SVR Class 14 Company Limited | Other services | 2014 |
| SW Legal Services Limited | Professional & scientific | 2013 |
| Swains of Stretton Limited | Financial services | 2010 |
| Swallow Court (Radford) Management Company Limited | Households | 2002 |
| Swallows Oak (2) Residents Association Limited | Households | 1991 |
| Swan Hill Studios Ltd | Arts & recreation | 2026 |
| Swan House Residents RTM Company Limited | Households | 2010 |
| Swan Mews (Lichfield) Residents Management Company Limited | Households | 2005 |
| Swan Therapy Hub Ltd | Health & social care | 2020 |
| Swancott Group Ltd | Construction | 2026 |
| Swansea Drain Services Limited | Water & waste | 2022 |
| SWC DMA Limited | Professional & scientific | 2021 |
| Swcbc DMA Ltd | Professional & scientific | 2021 |
| Sweet Clouds Limited | Wholesale & retail | 2025 |
| Sweet Shrewsbury Limited | Hospitality | 2016 |
| Sweet Sting Limited | Other services | 2023 |
| Sweetlake Business Village Management Limited | Real estate | 1998 |
| Sweetman Financial Planning Limited | Professional & scientific | 2019 |
| Swift Perry Holdings Limited | Professional & scientific | 2017 |
| Swigbars Ltd | Extraterritorial | 2025 |
| Swim Cloud Limited | Information & communication | 2016 |
| Swim With Style Franchising Ltd | Education | 2020 |
| Swimtime (UK) Ltd | Education | 2005 |
| Swimtime N.I. Limited | Other services | 2016 |
| Switch Associates Ltd | Administrative & support | 2021 |
| Switch Midlands CIC | Education | 2020 |
| Swoon Worthy Ltd | Other services | 2015 |
| Swqa Limited | Professional & scientific | 2015 |
| SWS Catering Limited | Hospitality | 2026 |
| SWS Collective Limited | Professional & scientific | 2025 |
| SY AG Supplies Ltd | Wholesale & retail | 2022 |
| SY Bamboo Limited | Hospitality | 2024 |
| SY Comms Ltd | Information & communication | 2024 |
| SY Construction Limited | Construction | 2019 |
| SY Contracts Ltd | Construction | 2022 |
| SY Homes (Albury Place) Limited | Construction | 2018 |
| SY Homes (Construction) Limited | Construction | 2019 |
| SY Homes (LH) Limited | Construction | 2019 |
| SY Homes (Shrewsbury) Limited | Construction | 2019 |
| SY Homes Limited | Construction | 2015 |
| SY Installs Ltd | Construction | 2026 |
| SY Legal Limited | Professional & scientific | 2025 |
| SY Logs Ltd | Wholesale & retail | 2019 |
| SY Plus Limited | Information & communication | 2026 |
| SY Pubs Ltd | Hospitality | 2025 |
| SY Robotics Ltd | Professional & scientific | 2025 |
| SY Stays Ltd | Real estate | 2024 |
| SY1 Consulting Limited | Professional & scientific | 2011 |
| SY1 Leisure Limited | Hospitality | 2025 |
| SY1 Limited | Other services | 2004 |
| SY2 Limited | Other services | 2007 |