| Stage and Studio Services Limited | Information & communication | 2014 |
| Stagedoor Studios and Academy CIC | Arts & recreation | 2026 |
| Stagetime International Limited | Arts & recreation | 2016 |
| Stags Legal Limited | Professional & scientific | 2026 |
| Stainless Design and Fabrications Limited | Manufacturing | 2001 |
| Stanfield Trading Ltd | Information & communication | 2021 |
| Stangrove Foods Ltd | Manufacturing | 2026 |
| Stanlemoore Limited | Hospitality | 2024 |
| Stanley Road (Stourbridge) Management Limited | Households | 2010 |
| Stannard Consultancy and Analytics Ltd | Information & communication | 2023 |
| Stanstock Events Limited | Administrative & support | 2015 |
| Stapeley Property Maintenance Ltd | Households | 2024 |
| Staples Property Solutions Ltd | Real estate | 2025 |
| Star Acts Productions Limited | Arts & recreation | 2019 |
| Star Barber(Shrewsbury) Ltd | Other services | 2020 |
| Star Cars Travel Ltd | Transport & logistics | 2018 |
| Star CUT Mardol Ltd | Other services | 2026 |
| Starfield Care Services Limited | Health & social care | 2022 |
| Start Tech Limited | Wholesale & retail | 2000 |
| Startlewood Properties Ltd | Real estate | 2016 |
| Startpad Limited | Administrative & support | 2016 |
| State Contracting Limited | Construction | 2024 |
| State Contracts Limited | Administrative & support | 2016 |
| Static Frequency Ltd | Arts & recreation | 2026 |
| Station Grill Limited | Hospitality | 2017 |
| Station Road (Park Gate) Management Company Limited | Households | 2006 |
| Station Road (Stoney Stanton) Management Limited | Households | 2006 |
| Station X Limited | Information & communication | 1999 |
| Station Yard Holdings (Hadnall) Ltd | Real estate | 2015 |
| Stationery Direct Ltd | Wholesale & retail | 2008 |
| Stay Loose Ltd | Hospitality | 2025 |
| Stayinshrewsbury.Com Ltd | Real estate | 2025 |
| Staynor Hall (Selby) Management Limited | Households | 2007 |
| STE Holdings Limited | Wholesale & retail | 2023 |
| Steadfast K9 Capability Support & Consultancy Ltd | Professional & scientific | 2026 |
| Steel Design Fabrications Limited | Manufacturing | 2008 |
| Stefanescu & Gavrila Ltd | Manufacturing | 2024 |
| Stellify Psychology Ltd | Health & social care | 2021 |
| Stennett Engineering Limited | Professional & scientific | 2013 |
| Stephanie Rose Fashion Ltd | Wholesale & retail | 2019 |
| Stephen Buss Environmental Consulting Limited | Professional & scientific | 2013 |
| Stephen Crossley Ltd | Transport & logistics | 2016 |
| Steppe in Ltd | Real estate | 2023 |
| Steve Bebb Building Services Ltd | Construction | 2024 |
| Steve Cowen Ltd | Professional & scientific | 2020 |
| Steve Lloyd Enterprises Limited | Professional & scientific | 2015 |
| Steve Seymour Holdings Limited | Financial services | 2004 |
| Steve Williams Plumbing & Heating Limited | Construction | 2008 |
| Stevenshoneyandbees Ltd | Manufacturing | 2023 |
| Stevenson Support Ltd | Information & communication | 2026 |
| Stew Properties Limited | Real estate | 2025 |
| Stewart Associates Ltd | Real estate | 2020 |
| Stewart Associates Shrewsbury Limited | Professional & scientific | 2008 |
| Stfc 2007 Limited | Other services | 2016 |
| Sthenosys Limited | Professional & scientific | 2004 |
| Stilemans Acre (Cressing) Management Company Limited | Households | 2011 |
| Stiperstone Group UK Ltd | Professional & scientific | 2026 |
| Stiperstones Consulting Limited | Information & communication | 2026 |
| Stiperstones JBJ Limited | Professional & scientific | 2014 |
| Stokes Farming Limited | Agriculture & fishing | 2024 |
| Stonebridge View Residents Management Company Limited | Households | 2018 |
| Stonebrook (Timperley) Estate Management Company Limited | Households | 2017 |
| Stonehouse Hill & Duxbury Ltd | Administrative & support | 2025 |
| Stonehurst Management (Shrewsbury) Limited | Households | 1997 |
| Stones Wharf (Weston Rhyn) Management Co Ltd | Households | 2023 |
| Stonetail Ltd | Wholesale & retail | 2014 |
| Stoney Racing Ltd | Wholesale & retail | 2012 |
| Stor Living Limited | Administrative & support | 2026 |
| Storage Solutions Shrewsbury Ltd | Transport & logistics | 2019 |
| Storm Property Services Ltd | Construction | 2019 |
| Stormer Hall Barns Management Company Limited | Households | 2022 |
| Stormwater Shepherds Enterprises Limited | Other services | 2021 |
| Story by Storey Ltd | Construction | 2023 |
| Storythreads Ltd | Professional & scientific | 2022 |
| Stour Mill (Ashford) Management Limited | Households | 1999 |
| Strada 14 Residents Association Limited | Households | 2004 |
| Straight Talk Mobile Limited | Wholesale & retail | 2017 |
| Strategic Transport Solutions International Limited | Professional & scientific | 2006 |
| Strategical Business Modelling Ltd | Information & communication | 2018 |
| Stratis Secure Ltd | Administrative & support | 2016 |
| Strativa HR Ltd | Professional & scientific | 2025 |
| Streamline Solution & Partners Limited | Information & communication | 2025 |
| Streamside (Flats) Management Limited | Real estate | 2021 |
| Street Food Ventures Limited | Hospitality | 2015 |
| Stretton Estate Management Limited | Real estate | 2013 |
| Stretton Hall Hotel Limited | Extraterritorial | 1998 |
| Strom Sports Ltd | Wholesale & retail | 2022 |
| Structural Glass Limited | Professional & scientific | 2007 |
| Stuart Devlin Limited | Manufacturing | 1977 |
| Stuart Duckett Electrical Ltd | Construction | 2006 |
| Stuart Potts Mortgage Services Ltd | Financial services | 2017 |
| Stuart Way (Ashby) Management Limited | Households | 2005 |
| Studio Acoustics UK Ltd | Construction | 2014 |
| Studio Barre LLP | | 2024 |
| Studio Bott Limited | Professional & scientific | 2019 |
| Studio BOZ Limited | Professional & scientific | 2025 |
| Studio Undercover Limited | Professional & scientific | 2022 |
| STUDIO3. Architecture & Planning Ltd | Professional & scientific | 2025 |
| Studycentral Limited | Education | 2006 |
| Stuffed in Shrewsbury Ltd | Manufacturing | 2014 |