| Designerkitchendirect Limited | Construction | 2016 |
| DESIGNERVARIETY0306 Limited | Wholesale & retail | 2024 |
| Designham Limited | Professional & scientific | 2021 |
| Designs for Life Ltd. | Manufacturing | 2000 |
| Designxy Ltd | Professional & scientific | 2018 |
| Desirable Carz Ltd | Wholesale & retail | 2023 |
| Desire Special Occasions Ltd | Hospitality | 2013 |
| Desitrack Ltd | Transport & logistics | 2026 |
| Desk Top Publications Ltd | Administrative & support | 2002 |
| Desktop Machine Shop Limited | Wholesale & retail | 2024 |
| Despoticsoft Ltd | Wholesale & retail | 2024 |
| Desq Limited | Information & communication | 2018 |
| Dessert Deluxe Ltd | Hospitality | 2025 |
| Dessert Time Sheffield Ltd | Hospitality | 2022 |
| Dessert Time Supplies Ltd | Hospitality | 2025 |
| Dessertheaven Ltd | Wholesale & retail | 2026 |
| Desserts Land Ltd | Hospitality | 2020 |
| Desserts Palace Ltd | Hospitality | 2021 |
| Destdol Limited | Professional & scientific | 2023 |
| Destratair Limited | Administrative & support | 2015 |
| Detailing Coach Ltd | Education | 2023 |
| Detand Properties Ltd | Other services | 2022 |
| Detaro Limited | Construction | 2007 |
| Detox Rehab Solutions Ltd | Wholesale & retail | 2025 |
| Deuce-Uk Limited | Other services | 2009 |
| Deutchoua Youani Health Care Limited | Health & social care | 2023 |
| DEV275 Ltd | Hospitality | 2026 |
| Deva Carpets Ltd | Wholesale & retail | 2023 |
| Devbear Ltd | Professional & scientific | 2024 |
| Develop Education Limited | Education | 2012 |
| Develop Minds Ltd | Administrative & support | 2011 |
| Develop Your Staff Ltd. | Professional & scientific | 2016 |
| Development Monkeys Ltd | Health & social care | 2024 |
| Developments by T&L2 Limited | Real estate | 2022 |
| Dever Holdings Limited | Financial services | 2020 |
| Devhouse Co Limited | Real estate | 2021 |
| Devils Pact Films Limited | Information & communication | 2025 |
| Devising Limited | Construction | 2018 |
| Devlet Health Ltd | Health & social care | 2017 |
| Devlin Music Limited | Information & communication | 2017 |
| Devloopr Web Solution Limited | Information & communication | 2024 |
| Devnsoft Ltd | Information & communication | 2019 |
| Devomni Limited | Information & communication | 2025 |
| Devon Aesthetics Limited | Other services | 2026 |
| Devon Lash X Ltd | Other services | 2022 |
| Devonbridge Limited | Real estate | 2016 |
| Devonshire Brands Ltd | Professional & scientific | 2025 |
| Devonshire Green (Broomgrove Road) Limited | Real estate | 2011 |
| Devonshire Green (City Living) Limited | Real estate | 2000 |
| Devonshire Green (Commercial Properties) Limited | Real estate | 2000 |
| Devonshire Green (Property Management) Limited | Households | 2000 |
| Devonshire Green (Residential Investments) Limited | Real estate | 2002 |
| Devonshire Green Holdings Limited | Real estate | 2000 |
| Devonshire Street Hospitality Limited | Hospitality | 2024 |
| Devonshire West Developments Limited | Construction | 2013 |
| Devora Limited | Information & communication | 2025 |
| Devoy Consulting Limited | Information & communication | 2026 |
| Devrim Zana Limited | Hospitality | 2019 |
| Dewsbury Developments Limited | Construction | 2013 |
| Dexameni Ltd | Wholesale & retail | 2024 |
| Dexel Holdings Ltd | Financial services | 2023 |
| Dexen Smith Limited | Manufacturing | 2024 |
| Dext Evolution Limited | Professional & scientific | 2018 |
| Dexter Cyberlab Ltd | Information & communication | 2025 |
| Dexter, Noble and Associates Limited | Professional & scientific | 2009 |
| Dexteritas Ltd | Administrative & support | 2019 |
| Dextron Technology Ltd | Professional & scientific | 2021 |
| DEY Building Services Ltd | Construction | 2021 |
| Deyar Properties Limited | Real estate | 2018 |
| Deyi Food Ltd | Wholesale & retail | 2021 |
| Dezignman Ltd | Construction | 2016 |
| DF Legal Consultancy Ltd | Financial services | 2026 |
| DF Projects Limited | Information & communication | 2024 |
| DF Psychology Ltd | Health & social care | 2026 |
| DFD Building and Paving Ltd | Construction | 2011 |
| Dfds Monteiro Ltd | Information & communication | 2025 |
| DFG Builders Ltd | Construction | 2019 |
| Dfgsecurity Ltd | Administrative & support | 2025 |
| DFH Designs Limited | Construction | 2005 |
| Dfin RT Limited | Information & communication | 2025 |
| DG Carpets & Vinyls Ltd | Construction | 2025 |
| DG Roofline Limited | Construction | 2020 |
| Dgcc Limited | Arts & recreation | 1995 |
| Dgdog Limited | Transport & logistics | 2024 |
| DGJ Installations Ltd | Construction | 2020 |
| DGK Medical Limited | Health & social care | 2019 |
| Dgmh Holding Ltd | Financial services | 2026 |
| DGR2025 Limited | Professional & scientific | 2025 |
| DH (UK) Limited | Construction | 1993 |
| DH Barber Ltd | Other services | 2022 |
| DH Housing Group Ltd | Construction | 2024 |
| DH Introducers Limited | Financial services | 2021 |
| DH Systems Ltd | Information & communication | 2005 |
| Dh&Z Ltd | Health & social care | 2024 |
| Dhaanya Indian Bar and Restaurent Ltd | Hospitality | 2025 |
| Dhana Ecom Group Limited | Wholesale & retail | 2025 |
| Dharti Ltd | Health & social care | 2025 |
| DHB Compressor Services Limited | Manufacturing | 2014 |
| DHB Projects Ltd | Construction | 2026 |
| Dhbl Services Ltd | Professional & scientific | 2025 |