| Stijl One Ltd | Construction | 2021 |
| Stildale Builders Limited | Construction | 2004 |
| Stildale Limited | Construction | 1996 |
| Still Learning Education CIC | Education | 2016 |
| Stirling Haven Limited | Real estate | 2026 |
| Stirling Motors Ltd | Wholesale & retail | 2021 |
| Stirling Potential Ltd | Professional & scientific | 2019 |
| Stitch Express Fargate Ltd | Other services | 2024 |
| Stitch N Print Limited | Manufacturing | 2007 |
| STL Pubs Limited | Hospitality | 2025 |
| Stlc Consultancy Limited | Information & communication | 2015 |
| STM 24 Healthcare Limited | Health & social care | 2026 |
| STM Automotive Ltd | Wholesale & retail | 2009 |
| Stoch Answers Ltd | Information & communication | 2024 |
| Stock Supplier (Active Wear) Ltd | Wholesale & retail | 2024 |
| Stockarth Project Solutions Limited | Professional & scientific | 2014 |
| Stockley MED Legal Services Ltd | Health & social care | 2012 |
| Stocklogiq Ltd | Wholesale & retail | 2019 |
| Stocksbridge and District Golf Club,Limited(The) | Arts & recreation | 1926 |
| Stocksbridge Aromatherapy Ltd | Wholesale & retail | 2025 |
| Stocksbridge Barber Salon Ltd | Other services | 2026 |
| Stocksbridge Community Care Group Ltd | Health & social care | 2008 |
| Stocksbridge Cricket Development Limited | Arts & recreation | 2025 |
| Stocksbridge Regeneration Company Limited | Construction | 2005 |
| Stocksbridge Rufc Limited | Arts & recreation | 2006 |
| Stocksbridge Works Cottage Trust Limited | Real estate | 1936 |
| Stockwell Accounting Limited | Professional & scientific | 2020 |
| Stockwell Finance Limited | Administrative & support | 2019 |
| Stogursey PUB Co Limited | Hospitality | 2021 |
| Stoica Transport Ltd | Transport & logistics | 2020 |
| Stoke Space Limited | Wholesale & retail | 2026 |
| Stoke Street Limited | Real estate | 2018 |
| Stoker Developments Limited | Real estate | 2021 |
| Stoker Group Limited | Real estate | 2021 |
| Stokes Holdings Ltd | Real estate | 2020 |
| Stolen Music Limited | Arts & recreation | 2020 |
| Stolen Publishing Limited | Information & communication | 2008 |
| Stolen Recordings Limited | Information & communication | 2006 |
| Stomp Clothing Limited | Wholesale & retail | 2007 |
| Stone Lodge Care Ltd | Health & social care | 2025 |
| Stone Mitchell Limited | Administrative & support | 2022 |
| Stone PM Ltd | Other services | 2017 |
| Stone the Crows Music Ltd | Arts & recreation | 2026 |
| Stoneacre Enterprises Ltd | Real estate | 2022 |
| Stonebridge Homes Group Limited | Financial services | 2019 |
| Stonebridge Homes Limited | Construction | 2010 |
| Stonebridge Offices Limited | Construction | 2011 |
| Stonecastle Cottages Ltd | Hospitality | 2024 |
| Stonecastle Holdings Ltd | Hospitality | 2023 |
| Stonecastle Properties Limited | Hospitality | 2015 |
| Stonecote Properties Limited | Real estate | 2025 |
| Stonecraft Restoration Ltd | Construction | 2018 |
| Stonecrescent Property Investment Ltd | Real estate | 2025 |
| Stoned ELF Limited | Administrative & support | 2009 |
| Stonedeaf Monsters Promotions Ltd | Arts & recreation | 2017 |
| Stoneface Creative Ltd | Arts & recreation | 2015 |
| Stoneglo Ltd | Manufacturing | 2024 |
| Stonehedge Homes Ltd | Health & social care | 2024 |
| Stonehouse Financial Services Ltd | Financial services | 2005 |
| Stonehouse Property Investment Limited | Real estate | 2022 |
| Stonelea Construction Ltd | Construction | 2026 |
| Stonenexus Ltd | Arts & recreation | 2012 |
| Stonenterprises (UK) Ltd | Wholesale & retail | 2014 |
| Stoneridge Properties Ltd | Real estate | 2023 |
| Stones Real Estate Ltd | Real estate | 2025 |
| Stones Throw DMS Limited | Professional & scientific | 2006 |
| Stonesgrove Properties Ltd | Real estate | 2025 |
| Stoney Music Limited | Arts & recreation | 2014 |
| Stonks Ltd | Wholesale & retail | 2023 |
| Stonx Ltd | Wholesale & retail | 2026 |
| Stop & Shop 247 Ltd | Wholesale & retail | 2025 |
| Stop First Limited | Manufacturing | 2006 |
| Storage & Transport Limited | Transport & logistics | 2019 |
| Storage and Machinery Services Limited | Professional & scientific | 1983 |
| Storage Singh Limited | Transport & logistics | 2019 |
| Storey Refrigerants Ltd | Wholesale & retail | 2019 |
| Storm Car Wash Limited | Administrative & support | 2020 |
| Storm DRY Ltd | Construction | 2025 |
| Storm Performance Entertainment Ltd | Other services | 2024 |
| Storm&Grace Limited | Wholesale & retail | 2015 |
| Storme Hair Limited | Manufacturing | 2021 |
| Storopack UK Limited | Manufacturing | 1967 |
| Storrs House Boarding Cattery Limited | Agriculture & fishing | 2016 |
| Storth Hollow Management Company Limited | Real estate | 2013 |
| Storth Park Management Limited | Households | 1975 |
| Storthwood Housing Management Company Limited | Households | 1982 |
| Storyboard Digital Ltd | Professional & scientific | 2024 |
| Storypunk Limited | Information & communication | 2017 |
| Stothard Supported Living Limited | Health & social care | 1992 |
| Stox Aluminium Ltd | Manufacturing | 2021 |
| Stox Construction Ltd | Construction | 2025 |
| STR Management Ltd | Real estate | 2023 |
| STR Site Engineering Limited | Other services | 2005 |
| STR8 Consulting Ltd | Professional & scientific | 2024 |
| Straaltechniek U.K. Limited | Manufacturing | 2000 |
| Strada Solutions Limited | Administrative & support | 2010 |
| Stradbroke Convenience Store Ltd. | Wholesale & retail | 2018 |
| Stradia Limited | Professional & scientific | 2006 |
| Strafford & Kent Limited | Construction | 2005 |
| Strafford Group Ltd | Real estate | 2026 |