| Sheltered Stability CIC | Real estate | 2024 |
| Shelton Medical Innovation Ltd | Professional & scientific | 2020 |
| Shemwell (Limb Lane) Limited | Real estate | 2022 |
| Shenell of Blessings Ltd | Wholesale & retail | 2026 |
| Sheng Tian Group Limited | Hospitality | 2023 |
| Sheng YUE Property Management Ltd | Hospitality | 2015 |
| Shenmei Media Ltd | Wholesale & retail | 2025 |
| Shenmei Trading Ltd | Wholesale & retail | 2025 |
| Shenmei Vision Ltd | Professional & scientific | 2025 |
| Shepherd Distribution Services Limited | Transport & logistics | 2010 |
| Shepherd Distribution Trustee Limited | Professional & scientific | 2022 |
| Shepherd Independent Financial Advisers Limited | Financial services | 2005 |
| Shepsgourmetkitchen Ltd | Hospitality | 2018 |
| Shepworth Construction Limited | Construction | 2014 |
| Shepworth Estates Ltd | Real estate | 2023 |
| Shepworth Renovations Ltd | Real estate | 2026 |
| Sheran Enterprise Ltd | Wholesale & retail | 2024 |
| Shergar Investments Group Limited | Transport & logistics | 2019 |
| Sherif Properties Limited | Real estate | 2019 |
| Sheriff Precision Abrasives Ltd | Manufacturing | 2021 |
| Sherwood Chase Flats Company Limited | Households | 1970 |
| Sherwood Forest Furniture Limited | Wholesale & retail | 2009 |
| Sherwood Promark Limited | Manufacturing | 1986 |
| Sheryl Findlay Coaching Limited | Other services | 2022 |
| Sheshadri Anaesthetics Ltd | Health & social care | 2022 |
| Shevdon Limited | Information & communication | 2008 |
| Shevon Limited | Wholesale & retail | 2025 |
| Shezeb Estates Ltd | Real estate | 2026 |
| SHF FTE Ltd | Hospitality | 2025 |
| SHF Property Limited | Real estate | 2019 |
| Shfld Estates Ltd | Real estate | 2026 |
| Shfld Holding Ltd | Real estate | 2026 |
| Shfld Property Holdings Ltd | Financial services | 2026 |
| Shgs Home Ltd | Construction | 2018 |
| SHH Autos Ltd | Manufacturing | 2024 |
| Shhhh! Coffee Shop Limited | Hospitality | 2013 |
| Shibba Ltd | Wholesale & retail | 2025 |
| Shibooi Limited | Information & communication | 2011 |
| Shield Commercial Estates Limited | Real estate | 2019 |
| Shield Passive Fire Ltd | Administrative & support | 2021 |
| Shield Projects Limited | Real estate | 2007 |
| Shield Secure Ltd | Administrative & support | 2017 |
| Shifa Aromas Ltd | Wholesale & retail | 2018 |
| Shika Rise Ltd | Wholesale & retail | 2024 |
| Shildon Forge Limited | Professional & scientific | 1984 |
| Shilohplace Limited | Health & social care | 2024 |
| Shine Imitation Ltd | Manufacturing | 2026 |
| Shine Learning and Training Centre CIC | Education | 2018 |
| Shine-Time Cleaning Ltd | Administrative & support | 2017 |
| Shinebridge Cleaning Group Ltd | Administrative & support | 2026 |
| Shineology Cleaning Services Ltd | Administrative & support | 2026 |
| Shinto Consulting Ltd | Information & communication | 2016 |
| Shinwari Cuisine Limited | Hospitality | 2023 |
| Shiny Happy People PUB Company Ltd | Hospitality | 2021 |
| Ship Shop Regeneration Limited | Real estate | 2011 |
| Shipshape Community Hub Ltd | Health & social care | 2015 |
| Shipston's Real Oak Floors Limited | Construction | 2022 |
| Shiraz Shic Limited | Wholesale & retail | 2012 |
| Shire Funeral Services Limited | Other services | 2025 |
| Shire Oaks Court Health Care Limited | Health & social care | 2022 |
| Shire Travel Limited | Administrative & support | 2014 |
| Shirebrook Cleaning Limited | Administrative & support | 2008 |
| Shirebrook Cohousing Limited | Hospitality | 2022 |
| Shirebrook Court Management Company Limited | Real estate | 2003 |
| Shirecliff Fish Bar Ltd | Hospitality | 2019 |
| Shiregreen Barber Ltd | Other services | 2023 |
| Shiregreen Foods Ltd | Hospitality | 2025 |
| Shiregreen Service Station Limited | Wholesale & retail | 2003 |
| Shirestone & Co Limited | Wholesale & retail | 2020 |
| Shirle Hill Ltd | Hospitality | 2013 |
| Shirt Prints Direct Ltd | Wholesale & retail | 2017 |
| Shisha Lounge Ltd | Other services | 2026 |
| Shisheen Trading Limited | Wholesale & retail | 2025 |
| Shishino Clothes Ltd | Wholesale & retail | 2025 |
| Shishino Trading Ltd | Wholesale & retail | 2025 |
| Shiva Health Ltd | Health & social care | 2014 |
| SHK 397 Ltd | Hospitality | 2024 |
| SHK Property Ltd | Real estate | 2025 |
| Shmm Enterprise Ltd | Wholesale & retail | 2025 |
| Shmoney Limited | Professional & scientific | 2020 |
| SHO Venture Ltd | Administrative & support | 2025 |
| Shocktech Suspension Limited | Wholesale & retail | 2015 |
| Shockwave Cheer and Dance Ltd | Arts & recreation | 2025 |
| Shokil Limited | Transport & logistics | 2025 |
| Shooz Buddy Limited | Wholesale & retail | 2025 |
| Shop & Shine Ltd | Wholesale & retail | 2019 |
| Shop & Smile Limited | Wholesale & retail | 2024 |
| Shop Displays Ltd | Construction | 2016 |
| Shop Furniture Limited | Wholesale & retail | 2024 |
| Shop With DW Ltd | Wholesale & retail | 2025 |
| Shop.Com Limited | Real estate | 1999 |
| SHOP4APROP Ltd | Construction | 2021 |
| Shopaholix Limited | Wholesale & retail | 2025 |
| Shopfield Limited | Wholesale & retail | 2019 |
| Shopfitters Yorkshire Ltd | Construction | 2015 |
| Shopflow Ltd | Wholesale & retail | 2025 |
| Shopfun Limited | Wholesale & retail | 2025 |
| Shopper Stop Ltd | Wholesale & retail | 2026 |
| Shoptale Limited | Wholesale & retail | 2025 |
| Shopwatch Ltd | Administrative & support | 2004 |