| ERB GAS Solutions Ltd | Professional & scientific | 2021 |
| Erbil Empire Ltd | Hospitality | 2020 |
| Erbin Limited | Hospitality | 2025 |
| ERD Consultants Ltd | Health & social care | 2025 |
| ERD Trade (Yorkshire) Ltd. | Administrative & support | 2020 |
| Erds Solutions & Services Limited | Information & communication | 2012 |
| Eremos Journeys Ltd | Administrative & support | 2025 |
| ERF Delivery Company Limited | Financial services | 2023 |
| Erfling Ltd | Wholesale & retail | 2023 |
| Ergo Industrial Flooring Ltd | Manufacturing | 2023 |
| Ergo Trinity Ltd | Professional & scientific | 2024 |
| Eribel Auto Repair Limited | Wholesale & retail | 2026 |
| Eric Stead (Garages) Limited | Wholesale & retail | 1964 |
| Eric Vines Limited | Real estate | 1963 |
| Erigo Distribution Limited | Information & communication | 2006 |
| Erigo Sales Ltd | Wholesale & retail | 2019 |
| Erimus Estates Limited | Real estate | 1999 |
| Erin Rose Property Limited | Real estate | 2024 |
| Erins Express Ltd | Hospitality | 2016 |
| Ernest Bennett & Company (Darlington) Limited | Manufacturing | 1964 |
| Ernest Bennett (Sheffield) Limited | Manufacturing | 1973 |
| Ernest H.Hill,Limited | Manufacturing | 1907 |
| Ernest Hinchliffe Limited | Manufacturing | 1934 |
| Ernest Jennings (Attercliffe) Limited | Wholesale & retail | 1968 |
| Ernest Thorpe & Company (Holdings) Limited | Financial services | 2014 |
| Ernest Thorpe & Company Limited | Wholesale & retail | 1954 |
| Ernest Thorpe Transport (Holdings) Limited | Financial services | 2014 |
| Ernest V. Waddington Limited | Wholesale & retail | 1949 |
| Ernest Wright Ltd | Manufacturing | 2018 |
| Erodatools Limited | Manufacturing | 1972 |
| Eros U Ltd | Wholesale & retail | 2025 |
| Errata Archives Ltd | Information & communication | 2021 |
| Ers-Uk Ltd | Water & waste | 2021 |
| Ersa UK Limited | Other services | 2005 |
| ERW Plant Hire Ltd | Administrative & support | 2026 |
| ERW Properties Ltd | Households | 2023 |
| Eryal Multimedia Hub Ltd | Information & communication | 2020 |
| ESA Auto Motive Ltd | Wholesale & retail | 2019 |
| ESA Cars Group Ltd | Administrative & support | 2025 |
| ESA Cars Ltd | Wholesale & retail | 2025 |
| Esah Corporate Investments Limited | Real estate | 2007 |
| Esarch Limited | Real estate | 2022 |
| ESB Digital Ltd | Professional & scientific | 2021 |
| Esbd Estates Ltd | Real estate | 2022 |
| Escafeld Consulting Ltd | Professional & scientific | 2022 |
| Escafeld Estates Limited | Households | 2001 |
| Escafeld Mechanical Services Limited | Professional & scientific | 2011 |
| Escafeld Properties Ltd | Real estate | 2023 |
| Escafield Property Ltd | Construction | 2021 |
| Escape 3D Ltd | Information & communication | 2022 |
| Escape Beyond Limited | Administrative & support | 2025 |
| Escape to the Wild Ltd | Professional & scientific | 2021 |
| Escape Wood & INK Limited | Manufacturing | 2026 |
| Escarzce Healthcare Ltd | Health & social care | 2026 |
| Escobars Coffee Ltd | Other services | 2024 |
| Esedra Ltd | Households | 2011 |
| ESH Brickwork Ltd | Construction | 2025 |
| Eshbilia Food Ltd | Hospitality | 2023 |
| Eshu Retail Limited | Administrative & support | 2016 |
| Esidarap Productions UK Limited | Construction | 2015 |
| ESJ Educational Psychology Ltd | Education | 2022 |
| ESJ Investments Limited | Real estate | 2020 |
| ESK Limited | Information & communication | 2015 |
| ESK20 Limited | Wholesale & retail | 2024 |
| Eski One Ltd | Health & social care | 2019 |
| Eskimoo Deserts Ltd | Hospitality | 2021 |
| Esland Enterprises Limited | Hospitality | 2025 |
| Esme Electrical Contractors Ltd | Construction | 2025 |
| Esme Group Ltd | Construction | 2015 |
| Esme Sales Ltd | Wholesale & retail | 2024 |
| Esme Solutions Ltd | Wholesale & retail | 2018 |
| Esme's House of Beauty Limited | Other services | 2025 |
| ESN Developments Limited | Construction | 2026 |
| ESN Ltd | Education | 2022 |
| ESP Projects Limited | Information & communication | 2002 |
| Espathome Limited | Information & communication | 2014 |
| Especially Gifted Ltd | Wholesale & retail | 2019 |
| Esperance Folk Ltd | Education | 2023 |
| Esportiv Ltd | Information & communication | 2022 |
| Espresso-Uk Limited | Hospitality | 2025 |
| Esps Consulting Ltd | Health & social care | 2024 |
| Espy Optical Ltd | Health & social care | 2023 |
| ESS Management Limited | Administrative & support | 2008 |
| Essar Construction Limited | Construction | 2019 |
| Essar Homes Limited | Real estate | 2022 |
| Essar Property Management Limited | Households | 2024 |
| Essenby Estates Limited | Real estate | 1997 |
| Essence Essential Ltd | Wholesale & retail | 2025 |
| Essence Wholesale Ltd | Wholesale & retail | 2026 |
| Essendine Crescent Ltd | Construction | 2025 |
| Essential Access Ltd | Professional & scientific | 2011 |
| Essential Property Care Ltd | Administrative & support | 2024 |
| Essential Sole Limited | Other services | 2025 |
| Essentials Media Limited | Manufacturing | 2022 |
| Essentials Nail and Skin Therapy Limited | Other services | 2007 |
| Essport Brickwork Limited | Construction | 2026 |
| EST Financial Ltd | Financial services | 2015 |
| Esta Medical Services Limited | Health & social care | 2015 |
| Estairs Ltd | Wholesale & retail | 2016 |
| Estate Maintenance Cleaning Services Limited | Administrative & support | 2012 |