| Elstree Couriers Limited | Transport & logistics | 2025 |
| Elsworth Acres Ltd | Real estate | 2008 |
| Eltezze Ltd | Wholesale & retail | 2024 |
| Eltio Studio Ltd | Professional & scientific | 2023 |
| Eltonkarena Limited | Health & social care | 2022 |
| Elurra White Assist Ltd | Health & social care | 2026 |
| Elusive Audio Limited | Manufacturing | 2013 |
| Elux Enterprise Ltd | Hospitality | 2024 |
| Elvaston Estates Limited | Real estate | 2013 |
| Elvenhome Limited | Construction | 2026 |
| Elvin Skin Health Clinic Ltd | Other services | 2025 |
| Elvuk Hospitality Ltd | Hospitality | 2025 |
| Elwood Electrical Solutions Ltd | Construction | 2023 |
| Elwyynn Productions Limited | Arts & recreation | 2011 |
| Eli̇tex Clothi̇ng UK Ltd | Wholesale & retail | 2020 |
| EMA Dental Solutions Ltd | Health & social care | 2012 |
| EMA Lettings Ltd | Real estate | 2022 |
| Emaan Trust of Sheffield | Other services | 2009 |
| Eman & Aaya Trading Limited | Hospitality | 2024 |
| Emane's Property Ltd | Real estate | 2025 |
| Emanuel Property Ltd | Real estate | 2020 |
| Emara Ltd | Wholesale & retail | 2010 |
| Emara Meat & Poultry Ltd | Manufacturing | 2017 |
| Emarket Deals Ltd | Professional & scientific | 2025 |
| Emaze Aesthetics Ltd | Health & social care | 2020 |
| Emazeinnerhealth Ltd | Wholesale & retail | 2025 |
| Embe Properties Limited | Real estate | 2017 |
| Ember Stoves Ltd | Construction | 2015 |
| Ember Transport Ltd | Transport & logistics | 2015 |
| Embleton Psychotherapy Limited | Health & social care | 2016 |
| Embrace (Sheff) Limited | Other services | 2018 |
| Embrace Beauty Ltd | Wholesale & retail | 2023 |
| Embs EOT Limited | Professional & scientific | 2024 |
| Emcd Engineering Limited | Professional & scientific | 2017 |
| Emco Construction Ltd | Construction | 2015 |
| Emco Developments Ltd | Financial services | 2022 |
| Emeg Rail Systems Limited | Construction | 2020 |
| Emelliy Coffee Limited | Hospitality | 2025 |
| Emerald Arrow Limited | Hospitality | 2025 |
| Emerald Bar & Restaurants Ltd | Hospitality | 2019 |
| Emerald Skin Care Ltd | Health & social care | 2010 |
| Emeraldlee Properties Ltd | Real estate | 2020 |
| Emergency Trauma Cleanup Ltd | Professional & scientific | 2016 |
| Emery Construction Systems Limited | Construction | 2008 |
| EMF Holdings Ltd | Real estate | 2018 |
| Emha Properties Ltd | Real estate | 2023 |
| Emilia Jean Care Limited | Public administration | 2020 |
| Emiliando Ltd | Wholesale & retail | 2023 |
| Emily Bridalwear Limited | Wholesale & retail | 2013 |
| Emily Forgot Ltd | Arts & recreation | 2011 |
| Emily Plumtree Translations Ltd | Professional & scientific | 2010 |
| Emily Stein Limited | Professional & scientific | 2022 |
| Emin Supermarkets Limited | Wholesale & retail | 2016 |
| Eminler Ltd | Wholesale & retail | 2020 |
| Emirate Estate Limited | Real estate | 2017 |
| Emma Ashford Ltd | Health & social care | 2023 |
| Emma Beci Ltd | Hospitality | 2021 |
| Emma Boileau Photography Limited | Professional & scientific | 2015 |
| Emma Cleave Limited | Information & communication | 2014 |
| Emma Ferriman Ltd | Health & social care | 2015 |
| Emma Marshall Consulting Ltd | Professional & scientific | 2022 |
| Emma Moore Design Limited | Professional & scientific | 2024 |
| Emma Murphy Coaching Ltd | Education | 2025 |
| Emma Murphy Companies Ltd | Professional & scientific | 2025 |
| Emma Richardson BA Services Limited | Administrative & support | 2022 |
| Emma Scarff Interior Design Limited | Professional & scientific | 2023 |
| Emma's Hair Room Limited | Other services | 2015 |
| Emmabella Healthcare Limited | Health & social care | 2015 |
| Emmalyn Limited | Health & social care | 2016 |
| Emmanuel Global Services Ltd | Health & social care | 2023 |
| Emmanuel Harmony Ltd | Health & social care | 2019 |
| Emmaus House CIC | Health & social care | 2021 |
| Emmess Holdings Limited | Financial services | 2022 |
| Emmess Limited | Construction | 2019 |
| Emmet House Management Limited | Real estate | 2004 |
| Emmetts Estates Limited | Real estate | 2021 |
| Emmetts Heating Ltd | Construction | 2013 |
| Emmetts Plumbing and Heating Limited | Construction | 2021 |
| Emmlove Limited | Professional & scientific | 2019 |
| Emmy Shop Ltd | Wholesale & retail | 2017 |
| Emnay Limited | Real estate | 2020 |
| Emons Group UK Limited | Transport & logistics | 2015 |
| Emootion Ltd | Professional & scientific | 2020 |
| Emora Ltd | Arts & recreation | 2025 |
| Emotional Finance Ltd | Administrative & support | 2024 |
| EMP Commerce Ltd | Wholesale & retail | 2025 |
| Empathy Healthcare Solutions UK Limited | Administrative & support | 2024 |
| Empathy Living Ltd | Health & social care | 2023 |
| Emperiox Global Ltd | Wholesale & retail | 2025 |
| Emperor Penguins Limited | Professional & scientific | 2016 |
| Emphasis Healthcare Limited | Health & social care | 2022 |
| Emphaty Care Ltd | Health & social care | 2023 |
| Empire Body Sculpting Ltd | Arts & recreation | 2025 |
| Empire Construction S4 Limited | Construction | 2024 |
| Empire Convenience Store Ltd | Wholesale & retail | 2014 |
| Empire Dream Limited | Professional & scientific | 2015 |
| Empire Fabrications & Installations Ltd | Manufacturing | 2025 |
| Empire Remapping Ltd | Wholesale & retail | 2025 |
| Empire Shopfitting Limited | Construction | 2017 |
| Employment Issues Limited | Professional & scientific | 2019 |