| Earth Property Rentals Limited | Real estate | 2024 |
| Earth Pulse Ltd | Wholesale & retail | 2023 |
| Earth-Tech Solutions Ltd | Professional & scientific | 2007 |
| Earthwork Plant Services (Yorkshire) Ltd | Administrative & support | 2017 |
| Easd Tech Ltd | Information & communication | 2023 |
| Ease Craft Ltd | Other services | 2022 |
| Ease Healthcare Ltd | Health & social care | 2016 |
| Ease Realty Ltd | Hospitality | 2023 |
| Ease Strategic Finance & Advisory (UK) Ltd | Professional & scientific | 2025 |
| Easel Peasel's Limited | Arts & recreation | 2019 |
| Easicam Ltd | Information & communication | 2010 |
| Easier Travel Limited | Administrative & support | 2018 |
| Easier Travel Services Limited | Administrative & support | 2024 |
| Eason Rose Limited | Financial services | 2014 |
| Easppubz Limited | Hospitality | 2026 |
| East HAM Regeneration Limited | Construction | 2014 |
| East Healing Ltd | Health & social care | 2022 |
| East Lodge Management Company Limited | Real estate | 2015 |
| East Midland Toy Company Limited | Wholesale & retail | 2013 |
| East Midlands Early Growth Fund Limited | Financial services | 2006 |
| East Midlands Garden Design Company Limited | Administrative & support | 2009 |
| East Midlands Leisure Services Limited | Wholesale & retail | 2024 |
| East OUT West Limited | Information & communication | 2025 |
| East Peak Countryside Associates Community Interest Company | Professional & scientific | 2012 |
| East Pennine Office Technology Limited | Administrative & support | 2003 |
| Eastbank Limited | Real estate | 2016 |
| Eastbourne Roofing Limited | Construction | 2018 |
| Eastell Consulting Limited | Administrative & support | 2002 |
| Eastell H&S Limited | Professional & scientific | 2026 |
| Eastell Surveying Ltd | Professional & scientific | 2025 |
| Easterly Road Carpets Ltd | Wholesale & retail | 2011 |
| Eastern European Delicatessen Ltd | Wholesale & retail | 2013 |
| Eastfield Place Management Yorkshire Limited | Households | 2023 |
| Eastlands Health Care Limited | Health & social care | 2008 |
| Eastman & Kirby Ltd | Health & social care | 2022 |
| Easton & Green Ltd | Construction | 2025 |
| Eastpoint Developments Ltd | Construction | 2015 |
| Eastville Autos Ltd | Wholesale & retail | 2025 |
| Eastwell Investments Limited | Construction | 2005 |
| Eastwood (Principals 2012) Limited | Professional & scientific | 2012 |
| Eastwood (Principals 2018) Limited | Professional & scientific | 2018 |
| Eastwood and Partners (Consulting Engineers) Limited | Professional & scientific | 1984 |
| Eastwood Bespoke Ltd | Extraterritorial | 2023 |
| Eastwood Property Consultants Ltd | Real estate | 2021 |
| Easy Home Builders Limited | Construction | 2026 |
| Easy Kare Ltd | Administrative & support | 2024 |
| Easy LET Angels Ltd | Real estate | 2019 |
| Easy Padel Ltd | Arts & recreation | 2025 |
| Easy PAY Europe Limited | Other services | 2025 |
| Easy Payment Solution Limited | Wholesale & retail | 2025 |
| Easy Rail Solutions Ltd | Construction | 2011 |
| Easy Task MAN & Van Limited | Water & waste | 2026 |
| Easy Tour Travel Ltd | Administrative & support | 2023 |
| Easy Way Letting Limited | Real estate | 2022 |
| Easy Wedge Ltd | Administrative & support | 2006 |
| Easyapplyuk Ltd | Professional & scientific | 2026 |
| Easycare Foundation Limited | Health & social care | 2002 |
| Easydemo Limited | Extraterritorial | 2000 |
| Easyfit Tyres and Automotive Services Ltd | Wholesale & retail | 2026 |
| Easystays Living Ltd | Hospitality | 2024 |
| Easytrainer.Com Limited | Extraterritorial | 2000 |
| EAT Great Meat Limited | Wholesale & retail | 2010 |
| EAT Sewa Ltd | Hospitality | 2026 |
| EAT Steak'D Ltd | Hospitality | 2025 |
| Eatables Limited | Hospitality | 2018 |
| Eatandbemerri Ltd | Wholesale & retail | 2023 |
| Eateom Publishing Ltd | Information & communication | 2012 |
| Eatoclock Zaika Limited | Hospitality | 2025 |
| Eaton & Booth (Sheffield) Limited | Professional & scientific | 1949 |
| Eaton Car Wash Ltd | Administrative & support | 2016 |
| Eatshed Sheffield Ltd | Manufacturing | 2018 |
| Eatsleepthink Design Limited | Administrative & support | 2002 |
| EB 74 Ltd | Transport & logistics | 2020 |
| EB Bars and Events Ltd | Hospitality | 2023 |
| EB Catering Limited | Hospitality | 2026 |
| EBB Properties Limited | Real estate | 2017 |
| EBC Properties Management and Lettings Ltd | Households | 2020 |
| Ebenezer Apartments Limited | Hospitality | 2019 |
| Ebenezer Mission Ltd | Health & social care | 2019 |
| Ebenezer Tackie Ltd | Transport & logistics | 2016 |
| Ebere& Ebere Ltd | Hospitality | 2023 |
| EBG Music Limited | Information & communication | 2017 |
| EBH Transport Ltd | Transport & logistics | 2024 |
| Ebistro Limited | Professional & scientific | 2017 |
| Ebisu Health Limited | Health & social care | 2017 |
| EBK Property Ltd | Real estate | 2024 |
| EBO Bakery Limited | Manufacturing | 2025 |
| Ebra Feast Ltd | Hospitality | 2026 |
| EC Group Recruitment Limited | Administrative & support | 2022 |
| EC1 Capital Limited | Financial services | 2011 |
| EC4 Global Ltd | Professional & scientific | 2025 |
| Ecai Ventures Limited | Professional & scientific | 2024 |
| ECC Healthcare Ltd | Health & social care | 2023 |
| ECC Lincoln City Clinic Limited | Health & social care | 2024 |
| ECC Logistics Ltd | Wholesale & retail | 2020 |
| ECC2 Ltd | Wholesale & retail | 2013 |
| Ecclesall Building Limited | Administrative & support | 2025 |
| Ecclesall Consultancy Ltd | Construction | 2011 |
| Ecclesall Design & Build Ltd | Construction | 2015 |
| Ecclesall Design Ltd | Construction | 2016 |