| Selby Building Plastics Ltd | Wholesale & retail | 2018 |
| Selby Car Sales Limited | Wholesale & retail | 2017 |
| Selby Community Recycling and Art Projects (S.C.R.A.P) Community Interest Company | Health & social care | 2016 |
| Selby Courthouse Limited | Real estate | 2017 |
| Selby District Association of Voluntary Service | Other services | 2011 |
| Selby District Disability Forum C.I.C. | Health & social care | 2016 |
| Selby District Vision | Administrative & support | 2012 |
| Selby Educational Trust | Education | 2016 |
| Selby Glass Limited | Construction | 2000 |
| Selby Golden Dragon Ltd. Limited | Hospitality | 2023 |
| Selby Golf Club,Limited(The) | Arts & recreation | 1913 |
| Selby Industrial Development Co.Limited | Construction | 1964 |
| Selby MOT Centre Limited | Professional & scientific | 2014 |
| Selby Office Services Limited | Administrative & support | 2018 |
| Selby Park Management Company (NO.2) Limited | Households | 1983 |
| Selby Prime Care Ltd | Health & social care | 2024 |
| Selby Removal Solutions Ltd | Water & waste | 2023 |
| Selby Store (Brook ST) Ltd | Wholesale & retail | 2025 |
| Selby Store Ltd | Wholesale & retail | 2020 |
| Selby Taxis Ltd | Transport & logistics | 2026 |
| Selby Trailer Hire Ltd | Administrative & support | 2024 |
| Selby Transport Services Limited | Transport & logistics | 2015 |
| Selby Vapes Ltd | Extraterritorial | 2020 |
| Selby World Travel Limited | Administrative & support | 1970 |
| SELBY73 Ltd | Hospitality | 2023 |
| Select Properties Ltd | Real estate | 2013 |
| Semperfli FLY Tying Materials Ltd | Manufacturing | 2014 |
| Senior Music Ltd | Arts & recreation | 2023 |
| Senna Investments Ltd | Real estate | 2024 |
| Serenity Studios Limited | Professional & scientific | 2010 |
| Serenity Supplies Ltd | Wholesale & retail | 2020 |
| Service Timber Properties Ltd | Other services | 2021 |
| Severn Healthcare Technologies Limited | Professional & scientific | 2012 |
| SG Planning Solutions Limited | Professional & scientific | 2012 |
| SGT Family Investments Ltd | Financial services | 2025 |
| SGT Property Investments Ltd | Real estate | 2025 |
| SGW Construction Limited | Construction | 2026 |
| Shared Vision Toolkit Limited | Professional & scientific | 2019 |
| Sheplam Ltd | Real estate | 2022 |
| Shield Direct Supplies Limited | Wholesale & retail | 2025 |
| Shield Environmental Solutions (Selby) Limited | Other services | 2012 |
| Shields DRY Limited | Administrative & support | 2008 |
| Shift Counselling Services Limited | Health & social care | 2019 |
| Shimrach Properties Limited | Real estate | 2022 |
| Shindig Event Styling Ltd | Administrative & support | 2021 |
| Shine 3P Limited | Administrative & support | 2016 |
| Shine Facilities Ltd | Administrative & support | 2013 |
| Ship Builders Credit Co Limited | Financial services | 2017 |
| Shipley Builders Ltd | Construction | 2002 |
| Shuttleworth Engineering Ltd | Construction | 2020 |
| Sibtomega Developments Limited | Real estate | 2024 |
| Sibtomega Limited | Construction | 1993 |
| Sidekickbox Ltd | Wholesale & retail | 2025 |
| Sight 4 Site Limited | Professional & scientific | 2014 |
| Sightlines Digital Limited | Professional & scientific | 2025 |
| Silfern Limited | Professional & scientific | 2008 |
| Silo Cleaning Services (UK) LLP | | 2011 |
| Silver Rose Entertainment Ltd | Information & communication | 2026 |
| Simnic Imports Limited | Wholesale & retail | 2014 |
| Simnic Properties Limited | Real estate | 2014 |
| Simnic-Uk Limited | Wholesale & retail | 2014 |
| Simon's School of Motoring Ltd | Education | 2024 |
| Simpson Cable Contractors Ltd | Construction | 2018 |
| Simpson Specialist Engineering Services Ltd | Construction | 2026 |
| Simulant Systems Ltd | Information & communication | 2012 |
| Siva Installs Ltd | Professional & scientific | 2021 |
| Sixfeetfive Ltd | Professional & scientific | 2025 |
| Sky Blue Contracts Ltd | Professional & scientific | 2007 |
| Sky Blue Face Mask Limited | Professional & scientific | 2021 |
| Sky Blue JET Turbine Limited | Wholesale & retail | 2022 |
| Skye Healthcare Limited | Health & social care | 2023 |
| Skyline (Yorkshire) Ltd | Construction | 2020 |
| Skyviews England Central Limited | Professional & scientific | 2000 |
| SL Marketing Services Limited | Professional & scientific | 2020 |
| Slater Scotney Consulting Ltd | Professional & scientific | 2024 |
| Slick Liquor Limited | Wholesale & retail | 2016 |
| Smarter Sharing Limited | Professional & scientific | 2024 |
| Smas Services Ltd | Administrative & support | 2026 |
| SMC Plastering Limited | Construction | 2005 |
| SMC Project Management Ltd | Professional & scientific | 2020 |
| Smilecrew Limited | Other services | 2025 |
| Smithfield Eggs (Yorkshire) Ltd | Agriculture & fishing | 2018 |
| Smithfield Eggs Limited | Agriculture & fishing | 2018 |
| Smiths Electrical Ltd | Construction | 2017 |
| Smithy's Management Company Limited | Real estate | 2018 |
| SML Cleaning Services Ltd | Administrative & support | 2026 |
| Snarf Inns & Country Pubs Limited | Hospitality | 2021 |
| SO Sound Design Ltd | Professional & scientific | 2015 |
| Social Dealer Solutions Limited | Professional & scientific | 2021 |
| Solbec Ltd | Education | 2015 |
| Solis Film Limited | Information & communication | 2016 |
| SP & a Investments Ltd | Real estate | 2018 |
| Spaces Enabled Limited | Construction | 2023 |
| Spaldington Resource Recycling Limited | Water & waste | 2005 |
| Spark Renewables Ltd | Construction | 2026 |
| Sparrck Ltd | Real estate | 2025 |
| Spartan Fit Limited | Other services | 2024 |
| Spartan Roofing Yorks Ltd | Construction | 2025 |
| SPE Engineering Ltd | Manufacturing | 2020 |
| Specialised Working Access Techniques Ltd | Professional & scientific | 2024 |