| Exel Enterprises Ltd | Wholesale & retail | 2024 |
| Exit Fire Safety Ltd | Other services | 2017 |
| Expert Automotive Scunthorpe Limited | Wholesale & retail | 2023 |
| Express Bullion Limited | Wholesale & retail | 2022 |
| Exton Industries Ltd | Professional & scientific | 2023 |
| Exton Motors Limited | Wholesale & retail | 2008 |
| Extreme Drives Ltd | Construction | 2025 |
| EYE Consultants Ltd | Health & social care | 2016 |
| EYE Mobility Ltd | Health & social care | 2007 |
| EYE Watch Security Limited | Administrative & support | 2002 |
| Ezmuve Estate Agents Limited | Real estate | 2015 |
| Ezra Lets Ltd | Real estate | 2021 |
| F M S Holdings (Scunthorpe) Limited | Financial services | 2011 |
| F. Cross & SON Limited | Wholesale & retail | 2011 |
| F. Trabalho Ltd | Wholesale & retail | 2024 |
| F4 Auto Repairs Ltd | Wholesale & retail | 2021 |
| FAB CAB Scunthorpe Ltd | Transport & logistics | 2026 |
| FAB Transport Services Ltd | Transport & logistics | 2022 |
| Fabihas Takeaway Ltd | Hospitality | 2025 |
| Fabulous Furniture Company Ltd | Manufacturing | 2018 |
| Facial Surgery (Nottingham) Limited | Health & social care | 2022 |
| Facial Surgery London Limited | Health & social care | 2018 |
| Fades and Shades Ltd | Other services | 2025 |
| Faheem Locum Services Ltd | Wholesale & retail | 2024 |
| Fair Share Glass Company Limited | Professional & scientific | 2008 |
| Fair Share Group Limited | Manufacturing | 2008 |
| Fair Share Newbuild Windows Limited | Professional & scientific | 2008 |
| Fairbanks Fabrication Limited | Construction | 2017 |
| Fake Baby Artistries Limited | Other services | 2013 |
| Falcon Group Enterprises Ltd | Real estate | 2023 |
| Falcon Victory Removals Ltd | Transport & logistics | 2024 |
| Falisha Limited | Hospitality | 2018 |
| Famali Homes Ltd | Real estate | 2026 |
| Famca Ltd | Health & social care | 2024 |
| Family of Hair Ltd | Wholesale & retail | 2012 |
| Fanica Transport Ltd | Transport & logistics | 2025 |
| Farnham Joinery (Lincs) Ltd | Construction | 2010 |
| Fashion Bargain Ltd | Wholesale & retail | 2017 |
| Fast Fit OUT Ltd | Construction | 2024 |
| Fast Tech Repair Limited | Other services | 2019 |
| Faster Fit Tyres Ltd | Wholesale & retail | 2012 |
| FC Haulage Ltd | Transport & logistics | 2024 |
| FDM Distribution Ltd | Transport & logistics | 2023 |
| Feel and Heal Ltd | Professional & scientific | 2026 |
| FEET2BEAT Community Interest Company | Arts & recreation | 2024 |
| FEN Properties Limited | Real estate | 1996 |
| Fender Steel Limited | Construction | 1981 |
| Fennell Holdings Limited | Wholesale & retail | 2019 |
| Fenton Orthopaedics Ltd | Health & social care | 2024 |
| Fenwick Engineering Limited | Manufacturing | 2020 |
| Fernandoboghiu Courier Ltd | Transport & logistics | 2025 |
| Fernwood Mews Management Company Limited | Households | 2016 |
| Ferry Boat Properties Limited | Real estate | 2020 |
| Ferry Boat PUB Company Limited | Hospitality | 2020 |
| Ferryboat Ltd | Hospitality | 2019 |
| Fervo MAR Ltd | Hospitality | 2026 |
| Fetch Solutions Ltd | Administrative & support | 2017 |
| FG Trucking Ltd | Transport & logistics | 2024 |
| FHR Group Ltd | Wholesale & retail | 2026 |
| Fibre Care Solutions Ltd | Other services | 2025 |
| Fibrecycle UK Limited | Manufacturing | 2009 |
| Field & Associated Services Limited | Administrative & support | 2023 |
| FINANCE@NO6 Ltd | Administrative & support | 2017 |
| Findlay & Scott Limited | Construction | 2000 |
| Finity IT Ltd | Other services | 2012 |
| Fire Engineering Services Limited | Construction | 2020 |
| Fire Protection Centre Limited | Wholesale & retail | 1999 |
| Fireflyx Limited | Information & communication | 2023 |
| Fireplace & Timber Products Limited | Construction | 2006 |
| First Call HSQ Limited | Professional & scientific | 2005 |
| First Choice Flooring & Beds Limited | Wholesale & retail | 2017 |
| Fish-A-Rama Ltd | Hospitality | 2022 |
| Fistiq Ltd | Wholesale & retail | 2025 |
| Fit Financial Services Limited | Professional & scientific | 2018 |
| Fit for FUN Fit for Adventure Ltd | Education | 2025 |
| Fitsorted Limited | Manufacturing | 2018 |
| FJG Management Limited | Financial services | 2015 |
| FJG Property LLP | | 2006 |
| FJG Property Management Ltd | Real estate | 2025 |
| Flamingo Flat Roofing Ltd | Construction | 2026 |
| Flavia-Maria Ltd | Health & social care | 2022 |
| Flavoured Kiss Ltd | Manufacturing | 2023 |
| Flaxmill Way Ltd | Construction | 2024 |
| Flex Competitions Limited | Wholesale & retail | 2023 |
| Flexy Mart Ltd | Wholesale & retail | 2026 |
| Floor & Wall Limited | Construction | 2004 |
| Flore&Lazar Cleaning Ltd | Administrative & support | 2025 |
| Florin Paraluta Transport Ltd | Transport & logistics | 2025 |
| Florin Transport Logistic Ltd | Transport & logistics | 2026 |
| Flowstrip Limited | Other services | 1981 |
| FMB Civil Engineering Ltd | Construction | 2020 |
| Follow the NUT Ltd | Wholesale & retail | 2021 |
| Food Manufacturing Process Solutions Ltd | Professional & scientific | 2020 |
| FOOD2GO Scunthorpe Ltd | Hospitality | 2024 |
| Foodworks UK Limited | Manufacturing | 2004 |
| For-Ward Planning Consultancy Limited | Administrative & support | 2007 |
| Forever Sisters Limited | Wholesale & retail | 2014 |
| Foreverknots Ltd | Wholesale & retail | 2022 |
| Forge Commercial Solutions Ltd | Financial services | 2025 |
| Forge Financial Solutions Ltd | Financial services | 2019 |