| DGN Haulage Ltd | Transport & logistics | 2024 |
| Diagnostic DOC Ltd | Wholesale & retail | 2017 |
| Diamant Ltd | Wholesale & retail | 2025 |
| Diamante Care Limited | Health & social care | 2023 |
| Diamond Aesthetics and Beauty Ltd. | Other services | 2020 |
| Diana RAY Ltd | Hospitality | 2024 |
| Dickinsons Engineering Services Ltd | Professional & scientific | 2021 |
| Diesel Exhaust Solutions Limited | Professional & scientific | 2025 |
| Digestive Health UK Limited | Health & social care | 2020 |
| Dillinger Saarstahl UK Limited | Professional & scientific | 2008 |
| Direct Renting Limited | Real estate | 2022 |
| Direct Reselling Ltd | Wholesale & retail | 2025 |
| Direct Sofas Ltd | Wholesale & retail | 2024 |
| Directions Dance Community Interest Company | Education | 2013 |
| Dirty Moon Ltd | Manufacturing | 2020 |
| Disaio Ltd | Transport & logistics | 2025 |
| Discount Pet Warehouse Limited | Wholesale & retail | 2012 |
| Discount Pound Shop Ltd | Wholesale & retail | 2025 |
| Divine Elegance Ltd | Other services | 2026 |
| DJ Taxis Scunthorpe Ltd | Transport & logistics | 2017 |
| Djgsurgical Limited | Health & social care | 2019 |
| DJM Autos Ltd | Wholesale & retail | 2026 |
| Djmo Food Ltd | Hospitality | 2025 |
| DJS Living Ltd | Real estate | 2025 |
| DJS Roofing Ltd | Construction | 2009 |
| DJS Service Centre Ltd | Wholesale & retail | 2023 |
| DJT Machining Services Ltd | Manufacturing | 2012 |
| DJW Asset Management Ltd | Professional & scientific | 2026 |
| DJW Services Limited | Professional & scientific | 2026 |
| DK & DR Ltd | Wholesale & retail | 2014 |
| DKB Crane Solutions Ltd | Construction | 2010 |
| DKP Hosting Ltd | Real estate | 2026 |
| DM Fordham Electrical Limited | Construction | 2012 |
| DMC Cleaning Services Ltd | Administrative & support | 2024 |
| DMK Property Solutions Ltd | Construction | 2025 |
| DMW Furniture Limited | Wholesale & retail | 2016 |
| DN Assessments Ltd | Construction | 2018 |
| DN Group (Lincs.) Ltd | Real estate | 2025 |
| DN Wright Ltd | Health & social care | 2022 |
| DNA Equestrian Limited | Wholesale & retail | 2022 |
| DNL Express Delivery Ltd | Transport & logistics | 2026 |
| DNM Consultancy Ltd | Information & communication | 2008 |
| DNT Recovery 24/7 Ltd | Wholesale & retail | 2025 |
| Dolphin HR Consultancy Limited | Administrative & support | 2012 |
| DOM Ophthalmics Ltd | Health & social care | 2025 |
| Dome Estates Limited | Real estate | 1994 |
| Donate Limited | Other services | 2026 |
| Donia Supermarket Scunthorpe Limited | Wholesale & retail | 2026 |
| Dons Builders Limited | Construction | 2006 |
| Doormats Online Limited | Wholesale & retail | 2014 |
| Dope Burger (Scunthorpe) Limited | Hospitality | 2023 |
| Dorin FSD Ltd | Other services | 2024 |
| Dorling Inspection Services Limited | Professional & scientific | 2017 |
| Double M Bookkeeping Services Limited | Professional & scientific | 2009 |
| Dove Engineering Consultancy Ltd | Professional & scientific | 2018 |
| Dove Valley (Ashbourne) Ltd. | Extraterritorial | 1961 |
| Doves Care Services Limited | Health & social care | 2023 |
| Dowden Capital (Grimsby) Limited | Financial services | 2024 |
| Downing Developments 14 LG Ltd | Real estate | 2024 |
| DP Cladding Ltd | Construction | 2022 |
| DPB Haulage Limited | Transport & logistics | 2012 |
| Dpgo Limited | Construction | 2020 |
| DR a M Harrison Coaching and Training Limited | Education | 2022 |
| DR AHB Ltd | Health & social care | 2023 |
| DR ALI Gondal Ltd | Health & social care | 2024 |
| DR Butt Healthcare Services Ltd | Health & social care | 2021 |
| DR Diab Haddad Ltd | Health & social care | 2018 |
| DR Diana Coffey Ltd | Professional & scientific | 2008 |
| DR Driving School Ltd | Education | 2026 |
| DR EE Ling Heng Limited | Health & social care | 2025 |
| DR Hajra Limited | Health & social care | 2023 |
| DR Jasmine Mann Limited | Health & social care | 2024 |
| DR Q Cardiology Limited | Health & social care | 2015 |
| DR Sami Ahmed Ltd | Health & social care | 2012 |
| DR Sidhu Medical Services Limited | Health & social care | 2023 |
| DR W DOW Ltd | Health & social care | 2019 |
| DR Wedad Abdelrahman Limited | Health & social care | 2022 |
| DRA Consultancy Limited | Professional & scientific | 2025 |
| Dragan Alin Ltd | Transport & logistics | 2025 |
| Dragomir Ltd | Transport & logistics | 2025 |
| Dragon Drop Studios Ltd | Information & communication | 2023 |
| Dragos Codrut One Ltd | Transport & logistics | 2023 |
| Drain Expert Solutions Ltd | Construction | 2026 |
| Drant's Plumbing & Heating Limited | Construction | 2014 |
| Draughts and Crafts Limited | Wholesale & retail | 2024 |
| Draytek Limited | Real estate | 2006 |
| DRC Engines Ltd | Wholesale & retail | 2024 |
| DRC Services Limited | Wholesale & retail | 2025 |
| Dream Leisure Decking Ltd | Wholesale & retail | 2022 |
| Dri-Home Limited | Construction | 1995 |
| Drinkall Joinery Limited | Construction | 2012 |
| Driver Call Group Limited | Transport & logistics | 2016 |
| Driver Rimas Ltd | Transport & logistics | 2016 |
| DRR People Limited | Professional & scientific | 2023 |
| Dryden Road 1972 Limited | Extraterritorial | 2013 |
| DSA Logistics Ltd | Transport & logistics | 2022 |
| DSC Retail (Lincs) Limited | Wholesale & retail | 2020 |
| DSM Assets Ltd | Real estate | 2026 |
| DSN Forum UK Ltd | Education | 2021 |
| DSS Property Investments Ltd | Real estate | 2021 |