| Elite Studios Centre Ltd | Administrative & support | 2025 |
| Elitedmic Limited | Real estate | 2020 |
| Elle 3 Ltd | Transport & logistics | 2017 |
| Ellerton Networking Ltd | Other services | 2024 |
| Eltome Apartments Limited | Households | 2005 |
| Embers Events Ltd | Hospitality | 2023 |
| Embers Restaurant Ltd | Hospitality | 2024 |
| Emce Solar Solutions Ltd | Energy | 2011 |
| Emea Semiconductor Limited | Information & communication | 2012 |
| Emem Limited | Health & social care | 2010 |
| Emerald Property Investments (Yorkshire) Ltd | Real estate | 2018 |
| Emerald Property Trading Ltd | Construction | 2022 |
| Emerson Survey and Valuation Ltd | Professional & scientific | 2015 |
| EMF Transport Limited | Transport & logistics | 2015 |
| EMG Research Limited | Professional & scientific | 2018 |
| Emily Edwards Limited | Professional & scientific | 2003 |
| Emily Saltmer Limited | Professional & scientific | 2021 |
| Emjr Property Limited | Real estate | 2024 |
| Emomation Limited | Other services | 2018 |
| Emotion Switch (Yorkshire) CIC | Education | 2022 |
| Emotion Switch Ltd | Education | 2016 |
| Emperial Solutions Ltd | Wholesale & retail | 2012 |
| Empire Grill Restaurants Ltd | Hospitality | 2024 |
| Emre Housing Ltd | Real estate | 2026 |
| Emtad Limited | Real estate | 2021 |
| Endcape Limited | Manufacturing | 1986 |
| Endcliffe Property Management Ltd | Real estate | 2023 |
| Enduro Tyres Limited | Manufacturing | 2014 |
| Enerdex Ltd | Energy | 2025 |
| Energy C Limited | Agriculture & fishing | 2003 |
| Engineering Recruitment Group Limited | Administrative & support | 2023 |
| English in Scarborough Ltd | Education | 2026 |
| Enhanced Managed Services Ltd | Information & communication | 2009 |
| ENS (Property) Limited | Other services | 2020 |
| Entangled States Limited | Information & communication | 2004 |
| Enterprise Cooling Services Ltd | Professional & scientific | 2024 |
| Enterprise Motors (2004) Limited | Wholesale & retail | 2004 |
| Enterprise Solutions (E-Sol) Limited | Information & communication | 2003 |
| Envirometrics Limited | Financial services | 1982 |
| Envision Holdings Limited | Financial services | 2024 |
| EPF Holdings Limited | Financial services | 2021 |
| Eptp 1175 (a) Limited | Professional & scientific | 2002 |
| Eptp 1175 (B) Limited | Professional & scientific | 2002 |
| Eptp 1175 (C) Limited | Professional & scientific | 2002 |
| Equibase UK Limited | Construction | 2013 |
| Erik Trans Logistic Ltd | Transport & logistics | 2026 |
| ERP Logistic Services Ltd | Hospitality | 2011 |
| Escape 2 the Sands Ltd | Real estate | 2007 |
| ESK Joinery Limited | Construction | 2023 |
| Esplanade Gardens Property Management Limited | Extraterritorial | 2005 |
| Eston Management Company Limited | Households | 1994 |
| Europe Market Scarborough Ltd | Wholesale & retail | 2023 |
| European Foods (Scarborough) Ltd | Wholesale & retail | 2023 |
| EVA Sofia Ltd | Transport & logistics | 2025 |
| Evergreen Touch Ltd | Health & social care | 2024 |
| Evergreen Trees and Shrubs Ltd | Wholesale & retail | 2002 |
| Everley London Ltd | Wholesale & retail | 2025 |
| Eves Vehicle Transport Ltd | Transport & logistics | 2025 |
| Evinance Property Ltd | Real estate | 2018 |
| Evolution Networking Ltd | Information & communication | 2010 |
| EW Sales Ltd | Wholesale & retail | 2025 |
| Exley Smith Electrical Limited | Construction | 2011 |
| Exploraboratory Ltd | Education | 2019 |
| EYM Associates Ltd | Real estate | 2023 |
| Eyre Scaffolding (Yorkshire) Ltd | Construction | 2013 |
| F a Stockill & SON Builders Limited | Real estate | 2003 |
| F Barker Building and Renovations Ltd | Construction | 2020 |
| F1 Investments Limited | Hospitality | 2009 |
| Fabraweld Limited | Manufacturing | 2008 |
| Face & Body Medispa Limited | Health & social care | 2021 |
| Fairbank the Baker Ltd | Manufacturing | 2009 |
| Falsgrave Food Limited | Hospitality | 2026 |
| Falsgrave Mini Market Ltd | Wholesale & retail | 2026 |
| Fanox Group Ltd | Wholesale & retail | 2024 |
| Fantasia Leisure Limited | Real estate | 2017 |
| Farmlytics Consulting Ltd | Professional & scientific | 2025 |
| Fashoda House Management Company Limited | Households | 2024 |
| Faultless Scaffolding Ltd | Construction | 2020 |
| Feather and FIN Limited | Arts & recreation | 2025 |
| Feathersmith Limited | Wholesale & retail | 2022 |
| Fenay Cottage Ltd | Hospitality | 2018 |
| Fencing Direct (Doncaster) Limited | Manufacturing | 2021 |
| Fibreform Ltd | Professional & scientific | 2014 |
| Fights and Fancy Ltd | Arts & recreation | 2023 |
| Filey Enterprises Limited(The) | Construction | 1922 |
| Filey Opticians Limited | Other services | 2012 |
| Filey Pets & Gardens Limited | Wholesale & retail | 2001 |
| Film Algarve Ltd | Information & communication | 2019 |
| Film Buddy Limited | Information & communication | 2015 |
| Film Portugal UK Ltd | Information & communication | 2019 |
| Filmify Ltd | Information & communication | 2021 |
| Financial PR Ltd | Professional & scientific | 2024 |
| Financial Wealth Solutions Limited | Financial services | 2015 |
| Finewood Properties Ltd | Real estate | 2022 |
| Finistere House Limited | Agriculture & fishing | 2020 |
| Finley Fishfingers Limited | Professional & scientific | 2026 |
| Fintry Residential Investments LLP | | 2009 |
| Fire & Environmental Property Services Ltd | Administrative & support | 2018 |
| Firk Inn Ltd | Hospitality | 2017 |
| Firmac Consulting Ltd | Professional & scientific | 2016 |