| Snaffyproperties Ltd | Real estate | 2025 |
| Snapik Limited | Wholesale & retail | 2025 |
| Snapshot (MCR) Ltd | Information & communication | 2013 |
| SND Capital Limited | Wholesale & retail | 2026 |
| Snook Investment Limited | Construction | 2023 |
| Snopix Ltd | Manufacturing | 2025 |
| Snowy Consultants Limited | Information & communication | 2023 |
| SNP Vape Limited | Wholesale & retail | 2023 |
| SNS Optical Limited | Health & social care | 2020 |
| SNZ Spices Limited | Hospitality | 2017 |
| SO (Manchester) Limited | Hospitality | 2023 |
| Soane Trans Ltd | Transport & logistics | 2016 |
| Soc-Healthcare Logistics Limited | Health & social care | 2026 |
| Soc-Med Ltd | Professional & scientific | 2015 |
| Soccer Stars Academy Greater Manchester East Ltd | Arts & recreation | 2023 |
| Socfeja Integrated Co. Ltd | Agriculture & fishing | 2023 |
| Social Mamba Ltd | Professional & scientific | 2025 |
| Social Sense Limited | Professional & scientific | 2011 |
| Socialatelierpr Limited | Professional & scientific | 2026 |
| Socialimpactmarketers Ltd | Professional & scientific | 2025 |
| Sodivone Ltd | Arts & recreation | 2021 |
| Sofiq Ltd | Information & communication | 2018 |
| Softclean Ltd | Wholesale & retail | 2018 |
| Sohl Shoes Ltd | Wholesale & retail | 2024 |
| Sokohomes Ltd | Households | 2026 |
| SOL Brazilian Food Ltd | Manufacturing | 2021 |
| Solar Maintenance Solutions Limited | Manufacturing | 2021 |
| Solaris Logistics Ltd | Transport & logistics | 2021 |
| Solfix Home Improvements Ltd | Construction | 2015 |
| Solian Cleaning Limited | Administrative & support | 2024 |
| Solid Cargo Ltd. | Transport & logistics | 2020 |
| Solis Vintage Limited | Wholesale & retail | 2023 |
| Solko Ltd | Wholesale & retail | 2025 |
| Solo Electrical Supplies Ltd | Wholesale & retail | 2017 |
| Solo Shot IT Ltd | Information & communication | 2025 |
| Solshore Limited | Extraterritorial | 1983 |
| Solum Regeneration (Bishops) LLP | | 2015 |
| Solum Regeneration (Epsom) Limited Partnership | | 2010 |
| Solum Regeneration (Greenwich) LLP | | 2012 |
| Solum Regeneration (Guildford) LLP | | 2015 |
| Solum Regeneration (Harrow) LLP | | 2015 |
| Solum Regeneration (Kingswood) LLP | | 2015 |
| Solum Regeneration (Redhill) LLP | | 2015 |
| Solum Regeneration (Surbiton) LLP | | 2015 |
| Solum Regeneration (Twickenham) LLP | | 2015 |
| Solum Regeneration (Walton) LLP | | 2015 |
| Solum Regeneration Epsom (GP Subsidiary) Limited | Extraterritorial | 2010 |
| Solum Regeneration Epsom (GP) Limited | Construction | 2010 |
| Solum Regeneration Epsom (Residential) LLP | | 2010 |
| Solum Regeneration Holding 1 LLP | | 2015 |
| Solum Regeneration Holding 2 LLP | | 2015 |
| Soluna Studios Ltd | Wholesale & retail | 2025 |
| Solutionpay UK Ltd | Professional & scientific | 2022 |
| Soma Property Ltd | Real estate | 2024 |
| Somek & Associates Limited | Professional & scientific | 2009 |
| Somen House Ltd | Hospitality | 2025 |
| Somervalley Limited | Professional & scientific | 2014 |
| Somitic Holdings Limited | Financial services | 2024 |
| Song Music Academy Ltd | Arts & recreation | 2020 |
| Songbirds Music Ltd | Arts & recreation | 2022 |
| Songbirds Music UK CIC | Information & communication | 2019 |
| Sonic Temple Ltd | Wholesale & retail | 2024 |
| Sonic Virtual Office Limited | Administrative & support | 2025 |
| Sonicspeed Couriers Limited | Transport & logistics | 2024 |
| Sonova Ventures Limited | Professional & scientific | 2024 |
| Soreg Limited | Professional & scientific | 2017 |
| Soufflet Agriculture Limited | Wholesale & retail | 1984 |
| Soul Medicare Ltd | Administrative & support | 2019 |
| Soul Retreat and Travel Limited | Other services | 2026 |
| Soumaye Enterprise Limited | Administrative & support | 2025 |
| Sourpuss Studios Ltd | Information & communication | 2025 |
| South Elmsall Real Estate Limited | Professional & scientific | 2009 |
| South Marston SPV Limited | Real estate | 2025 |
| South Securities 2 Limited | Real estate | 2024 |
| South Securities Limited | Real estate | 2024 |
| Southampton Estates Ltd | Other services | 2018 |
| Southborough Management Company Limited | Households | 2022 |
| Southern Staffing Group UK Ltd | Administrative & support | 2025 |
| Southern Zone Management Company Limited | Households | 2022 |
| Southton Services Ltd | Information & communication | 2019 |
| SOV Properties Ltd | Real estate | 2020 |
| Sovereign Capital Alliance Limited | Administrative & support | 2024 |
| Sowcrest Limited | Real estate | 1994 |
| Sowmyadevi Painting Ltd | Construction | 2025 |
| Sozz Ltd | Health & social care | 2023 |
| SP Management M/C Ltd | Real estate | 2025 |
| SP Online Ltd | Wholesale & retail | 2023 |
| SP Simmons Limited | Wholesale & retail | 2007 |
| Spa & Style Ltd | Other services | 2025 |
| Spa Servcom Ltd | Transport & logistics | 2026 |
| Spacedit Ltd | Administrative & support | 2026 |
| Spacemade Estates Limited | Other services | 2023 |
| Spacetalk Limited | Hospitality | 1999 |
| Spacevac Ltd | Administrative & support | 2024 |
| Spalding Way Management Company Limited | Real estate | 2024 |
| Spanish-French-Portuguese Support Group Manchester CIC | Health & social care | 2024 |
| Sparehomes Relocation LLP | | 2024 |
| Sparkforce Service Ltd | Administrative & support | 2025 |
| Sparkle Ease Ltd | Administrative & support | 2024 |
| Sparkle Specialists Ltd | Administrative & support | 2022 |