| Roboto Systems Ltd | Wholesale & retail | 2012 |
| Robrad Ltd | Wholesale & retail | 2022 |
| Rochmere Country Park Management Company Limited | Households | 2002 |
| Rock Avenue Properties Limited | Real estate | 2025 |
| Rock Garage Limited | Wholesale & retail | 2002 |
| Rocket Science Productions Limited | Information & communication | 2022 |
| Rodney Todd-White & SON Limited | Professional & scientific | 2004 |
| ROE Green Construction Limited | Construction | 2024 |
| Roger Street Investments Limited | Construction | 1995 |
| Roger Taylor Associates (Hospitality) Limited | Administrative & support | 2009 |
| Rolisma Limited | Information & communication | 2018 |
| Romada Retail Limited | Wholesale & retail | 2023 |
| Romford Road 1969 Limited | Extraterritorial | 2014 |
| RON IT Limited | Information & communication | 2012 |
| Ronak Food Ltd | Hospitality | 2025 |
| Roof Protection Ltd | Construction | 2015 |
| Roofclad Limited | | 1982 |
| Rooted Media Ltd | Information & communication | 2025 |
| Rose & Rose Properties Limited | Real estate | 2019 |
| Rose Market PVT Ltd | Wholesale & retail | 2025 |
| Rosedale Management Company Limited | Households | 1989 |
| Roselands (Harboro Road Sale) Management Company Limited | Households | 2004 |
| Roseneath House Management Company Limited | Real estate | 2007 |
| Rosetta Design Limited | Professional & scientific | 2024 |
| Ross Macleod Education Services Limited | Education | 2013 |
| Rosy Dragon Ltd | Administrative & support | 2024 |
| Round Creative Ltd | Arts & recreation | 2011 |
| Roundhey Care Limited | Health & social care | 2015 |
| Roundhouse Care Holdings Limited | Financial services | 2018 |
| Roxy’S Creations Ltd | Arts & recreation | 2023 |
| RPC Properties and Lettings Ltd | Real estate | 2022 |
| RPR Homes Ltd | Real estate | 2018 |
| RR Space Limited | Real estate | 2018 |
| Rrasgulati Ltd | Health & social care | 2020 |
| RRP Group Trade Private Limited | Wholesale & retail | 2019 |
| RS Control Services Limited | Construction | 2009 |
| RSH Medical Device Consulting Ltd | Wholesale & retail | 2021 |
| RSK Consulting Limited | Information & communication | 2015 |
| RT Stores Limited | Wholesale & retail | 2022 |
| Rubies Cafe Ltd | Hospitality | 2024 |
| Rubies Recruitment Ltd | Professional & scientific | 2018 |
| Ruby Star Investments Ltd | Financial services | 2021 |
| Rudy & Co Petcare Limited | Wholesale & retail | 2025 |
| Rumlone Limited | Real estate | 1980 |
| Rumrabbitrun Ltd | Hospitality | 2022 |
| Run DMM Limited | Hospitality | 2019 |
| Runaiah Holdings Limited | Real estate | 2025 |
| Rushmere Classic Cars Ltd | Wholesale & retail | 2022 |
| Russell Bolton Consulting Limited | Professional & scientific | 2020 |
| Russell Platt Associates Limited | Professional & scientific | 2008 |
| Russit Limited | Information & communication | 2013 |
| Rvdl Developments Ltd | Construction | 2016 |
| RW Consulting Services Ltd | Professional & scientific | 2022 |
| RW Enterprises Ltd | Hospitality | 2024 |
| RW Jupe Acquisitions Limited | Manufacturing | 2017 |
| RW Jupe Limited | Financial services | 2024 |
| Ryan Mulvey Ltd | Arts & recreation | 2025 |
| Ryder Garage Equipment Ltd | Manufacturing | 2025 |
| RZ Eagle Ltd | Real estate | 2022 |
| S & D Leisure (Europe) Limited | Arts & recreation | 1999 |
| S & D Leisure Manchester Limited | Hospitality | 2011 |
| S & I Groundworks Limited | Construction | 2014 |
| S & L Health Limited | Health & social care | 2013 |
| S D Waste Paper Limited | Water & waste | 2016 |
| S Handford Legal Services Ltd | Professional & scientific | 2023 |
| S J Duckworth Limited | Administrative & support | 2011 |
| S J Salon Ltd | Other services | 2023 |
| S J T Enterprises Northern Ltd | Transport & logistics | 2016 |
| S R Coaching Limited | Arts & recreation | 2026 |
| S R Kitchen Ltd | Hospitality | 2019 |
| S&A Pride Limited | Real estate | 2024 |
| S&L Accountants Ltd | Professional & scientific | 2021 |
| S&S Home Investments Ltd | Real estate | 2025 |
| S.A Journals Limited | Information & communication | 2024 |
| S.L. Transport (UK) Limited | Transport & logistics | 1991 |
| S.O AA Property Ltd | Construction | 2026 |
| S.Sbr Ltd | Real estate | 2010 |
| S16 Ltd | Manufacturing | 2017 |
| Saannya Works Limited | Information & communication | 2026 |
| Sabah Studio Ltd | Wholesale & retail | 2025 |
| Sabiduria Ltd | Financial services | 2012 |
| Sabili Limited | Professional & scientific | 2022 |
| Sabir Properties Northwest Ltd | Real estate | 2025 |
| Sabitha Systems Limited | Information & communication | 2014 |
| Sabo Developments Limited | Construction | 2024 |
| Sachneha Homes Limited | Real estate | 2018 |
| Sadic Property Management Ltd | Real estate | 2014 |
| Sadore Holdings Ltd | Financial services | 2020 |
| Safwan Ltd | Health & social care | 2014 |
| SAI Barbers Ltd | Other services | 2025 |
| Saibiz Ltd | Information & communication | 2012 |
| Saiverse IT Limited | Information & communication | 2026 |
| Sale Area Model Engineering Society Limited | Other services | 1998 |
| Sale Body Repair Centre Ltd | Wholesale & retail | 2019 |
| Sale Body Repair Centre Manchester Ltd | Wholesale & retail | 2023 |
| Sale Car and Commercial Body Repair Centre Ltd | Wholesale & retail | 2022 |
| Sale Caterers Ltd | Hospitality | 2022 |
| Sale Cricket Ground Company Limited(The) | Arts & recreation | 1911 |
| Sale Dental Spa Limited | Health & social care | 2014 |
| Sale Football Club Company Limited | Arts & recreation | 1920 |