| Dabodes Ltd | Real estate | 2018 |
| DAG Haulage Ltd | Transport & logistics | 2016 |
| Dahlia and DE Renzy Limited | Wholesale & retail | 2025 |
| Daily Clean 24SEVEN Ltd | Extraterritorial | 2012 |
| Dainton Properties Limited | Construction | 2017 |
| Dakh Developments Limited | Construction | 2025 |
| Danoz Consulting Limited | Professional & scientific | 2024 |
| Daphnerosa Ltd | Wholesale & retail | 2014 |
| Dardy Technologies UK Limited | Real estate | 2016 |
| DAS Business Furniture Limited | Administrative & support | 1985 |
| Data Procurement Network Ltd | Information & communication | 2024 |
| Datecontrol Property Management Limited | Households | 1993 |
| Dato Build Limited | Construction | 2026 |
| Davenport Bernard Consulting Limited | Professional & scientific | 2020 |
| David Magness Farms Limited | Agriculture & fishing | 1975 |
| David Turner & Co Limited | Agriculture & fishing | 2010 |
| David W M Cotier C0272 Ltd | Transport & logistics | 2003 |
| Davidson Investments 2019 Ltd | Real estate | 2019 |
| Dawfern Developments Ltd | Construction | 2020 |
| Daww Consultancy Ltd | Professional & scientific | 2024 |
| Dayglow Media Ltd | Information & communication | 2016 |
| Daylinks Ltd | Manufacturing | 2013 |
| Days of Your Life Limited | Wholesale & retail | 2006 |
| DB Coaching & Development Ltd | Professional & scientific | 2021 |
| DBX Services Limited | Information & communication | 2007 |
| DCB VET Limited | Financial services | 2022 |
| DE Vele Homes Limited | Construction | 2024 |
| DE Vere Hammond Wealth Management Ltd | Financial services | 2013 |
| Debden Community Shop Limited | Wholesale & retail | 2019 |
| Debolex Limited | Manufacturing | 2014 |
| Deep Clean 24SEVEN Ltd | Extraterritorial | 2013 |
| Deeper Into Movies Limited | Information & communication | 2019 |
| Defence & Security Equipment International Limited | Administrative & support | 2007 |
| Dejavu Aberdeen Ltd | Hospitality | 2023 |
| Della Green Limited | Administrative & support | 2008 |
| Delmon Trading Ltd | Wholesale & retail | 2016 |
| Delta Woodfinishing Limited | Professional & scientific | 2016 |
| Dementia Life CIC | Education | 2025 |
| Demonchaux Investments Ltd | Construction | 2025 |
| Dencora Foods Limited | Manufacturing | 2026 |
| Denise Mathieson Consulting Limited | Professional & scientific | 2026 |
| Deniz Limited | Wholesale & retail | 2012 |
| Dermax Aesthetics UK Limited | Other services | 2025 |
| Desco Holdings Limited | Other services | 2007 |
| Design Coalition Co. Limited | Professional & scientific | 2001 |
| Design Motive Limited | Arts & recreation | 1992 |
| Development Inc Ltd | Professional & scientific | 2013 |
| Developmestudio Ltd | Professional & scientific | 2025 |
| Devtec Limited | Real estate | 2007 |
| DF Ltd | Extraterritorial | 2008 |
| DG Performance & Tuning Ltd | Wholesale & retail | 2022 |
| DGE Property Ltd | Real estate | 2026 |
| DGS Decorating Services Limited | Other services | 2015 |
| Dhanjal Medical Ltd | Health & social care | 2023 |
| Diagnostics for the Real World (Europe) Limited | Manufacturing | 2006 |
| Diagtronics Ltd | Other services | 2024 |
| Dialeg Ltd | Professional & scientific | 2017 |
| Diamond Engineering Ltd | Manufacturing | 1980 |
| Diamond Forever LLP | | 2025 |
| Diamond Strategic Ltd | Manufacturing | 2018 |
| Dice Dynamics Limited | Professional & scientific | 2016 |
| Dickinson-Adams Limited | Manufacturing | 2023 |
| Diggines Associates Limited | Professional & scientific | 2003 |
| Digital Poster Limited | Extraterritorial | 2006 |
| Digital Posters Limited | Extraterritorial | 2006 |
| Digital Success Consulting Limited | Professional & scientific | 2023 |
| Digitech IT Solutions Ltd | Information & communication | 2023 |
| Dirtymouth Cupcakes LDN Limited | Hospitality | 2015 |
| Disc Makers Limited | Other services | 2005 |
| Distinction Business Consulting Limited | Professional & scientific | 2021 |
| Diversifying Strategies Limited | Financial services | 2020 |
| DJ Coles Services Limited | Construction | 2012 |
| DK Ltd | Extraterritorial | 2009 |
| DKL Pallets Ltd | Wholesale & retail | 2018 |
| DL Ltd | Extraterritorial | 2008 |
| Dman Ltd | Real estate | 2024 |
| Dman Properties LLP | | 2024 |
| DMJ Equity Analysis Ltd | Professional & scientific | 2019 |
| DMJ Hector Ltd | Construction | 2020 |
| DNT Hoists Limited | Manufacturing | 2024 |
| DO DA Werk Limited | Education | 2022 |
| DO Ltd | Extraterritorial | 2025 |
| DO Pilates Limited | Arts & recreation | 2006 |
| Doctor Eliza Limited | Health & social care | 2024 |
| Dog-Ease Ltd | Administrative & support | 2021 |
| Dogoffice IT Services Limited | Information & communication | 2015 |
| Dokcharts Ltd | Information & communication | 2022 |
| Domainex Limited | Professional & scientific | 2001 |
| Dominee Limited | Professional & scientific | 2014 |
| Dominion Properties and Investments Limited | Real estate | 2011 |
| Donald Purkiss & Associates LLP | | 2010 |
| Dorie Investments Limited | Construction | 2017 |
| Dorodvand Developments Ltd | Construction | 2020 |
| Dorset UK Ltd | Extraterritorial | 2018 |
| DOT Dash CAM Limited | Professional & scientific | 2010 |
| Dover Plumbing and Heating Limited | Construction | 2002 |
| Dowd & Company Limited | Administrative & support | 1997 |
| Down Cold Productions Limited | Information & communication | 2002 |
| Downham Consulting Limited | Professional & scientific | 2025 |
| Doyle Executive Management Limited | Professional & scientific | 2015 |