| ST Marys House (Ryde) Management Company Limited | Administrative & support | 1996 |
| ST. Margaret's Court Management Company Limited | Professional & scientific | 1979 |
| Starlight Fizz Ltd | Information & communication | 2017 |
| Steed Harris & Company Limited | Professional & scientific | 2002 |
| Steep Hill Down Limited | Construction | 2022 |
| Stevens Joinery Ltd | Manufacturing | 2024 |
| Stevens Services (West END) Limited | Manufacturing | 1999 |
| Stevens Washrooms Holdings Limited | Financial services | 2018 |
| Stitch Department CIC | Manufacturing | 2021 |
| Stonepitts House Management Company Limited | Other services | 1982 |
| Stratease Limited | Professional & scientific | 2020 |
| Studiophase Limited | Information & communication | 1986 |
| SUBCON1 Limited | Manufacturing | 2025 |
| Sun, Sea and Souvenirs Limited | Wholesale & retail | 2019 |
| Sunny Stone Holdings Ltd | Wholesale & retail | 2018 |
| Surenav Ltd | Professional & scientific | 2017 |
| Sureweld Engineering Limited | Manufacturing | 2014 |
| Susan Payne Property Ltd | Administrative & support | 2017 |
| SZ & SM Properties Ltd | Real estate | 2023 |
| T S Electrical (IW) Limited | Construction | 2023 |
| T. Kerr & Sons Limited | Real estate | 1964 |
| T2 Design Services Limited | Professional & scientific | 2022 |
| Tackt-Isle Adventures Limited | Administrative & support | 2012 |
| Tanishas Kitchen Limited | Hospitality | 2023 |
| Tapthemarket Limited | Professional & scientific | 2019 |
| Tea Table Sporting Kennels Limited | Other services | 2022 |
| Tebihost Limited | Information & communication | 2010 |
| Techlec Limited | Construction | 2008 |
| Tenant Landlord Central Ltd | Real estate | 2020 |
| Terry's Takeaway Ltd | Hospitality | 2018 |
| THE 101 Collective Ltd | Information & communication | 2022 |
| THE Beach HUT Company (Colwell Bay) Limited | Real estate | 2012 |
| THE Best Dressed Crab Limited | Wholesale & retail | 2012 |
| THE Big Sleepover at the White House Ltd | Arts & recreation | 2017 |
| THE Binstead Arms Limited | Hospitality | 2022 |
| THE Black Seagull Limited | Hospitality | 2011 |
| THE Boltons Kite Hill Residents Association Limited | Other services | 1997 |
| THE Botany Consultancy Ltd | Professional & scientific | 2021 |
| THE Cleaner Company (IOW) Ltd | Administrative & support | 2020 |
| THE Clear Advice Group Limited | Financial services | 2006 |
| THE Crusaders' Union | Other services | 2011 |
| THE Duck (IOW) Limited | Hospitality | 2016 |
| THE EAR Specialist (IOW) Ltd | Wholesale & retail | 2024 |
| THE F.I.R.S.T Hub (Family IOW Relationship Support Team) CIC | Health & social care | 2022 |
| THE Food Hamper Cowes Ltd | Hospitality | 2020 |
| THE Goose Books Ltd | Wholesale & retail | 2019 |
| THE Greta PUB Company Limited | Hospitality | 2025 |
| THE House Clinic Limited | Other services | 2024 |
| THE Island Holiday Company Ltd | Hospitality | 2020 |
| THE Islander Apparel Ltd | Wholesale & retail | 2025 |
| THE Isle of Wight Lettings Company Ltd | Households | 2025 |
| THE Lanternians Ltd | Households | 2020 |
| THE Little Island Carpentry Co Limited | Construction | 2021 |
| THE Mind Boutique Limited | Extraterritorial | 2011 |
| THE Mustard Club Limited | Hospitality | 2013 |
| THE Nail Guys Ltd | Other services | 2025 |
| THE New Carnival Company CIC | Other services | 2011 |
| THE Osborne Cleaning Company Limited | Administrative & support | 2016 |
| THE Otto Club Limited | Hospitality | 2019 |
| THE Pavilion Rise Easthill Road Residents Association Limited | Households | 1997 |
| THE Phoenix Project (IOW) | Health & social care | 2011 |
| THE Piano Cafe (IOW) Ltd | Hospitality | 2021 |
| THE Red Seagull Limited | Hospitality | 2017 |
| THE Solar MAN IOW Ltd | Administrative & support | 2025 |
| THE Sports Shop (IOW) LLP | | 2017 |
| THE Tree Shelter Company Limited | Manufacturing | 2011 |
| THE Vegetable Cart Ltd | Wholesale & retail | 2023 |
| THE Veteran CIC | Other services | 2022 |
| THE Veterans Hub (IOW) C.I.C. | Other services | 2020 |
| THE Wight Seagull Limited | Hospitality | 2010 |
| THE Wonky Goat Ltd | Hospitality | 2020 |
| Theatre Educational Ltd | Extraterritorial | 2019 |
| Theatre Reviva! CIC | Arts & recreation | 2021 |
| Theodora Swimming Ltd | Education | 2017 |
| Thesaurus Limited | Information & communication | 2022 |
| Thinking Finance UK Limited | Financial services | 2007 |
| Thomas Court (IW) Limited | Households | 2022 |
| Thorben James Limited | Professional & scientific | 2018 |
| Thump Studio Ltd | Professional & scientific | 2021 |
| Tidal Wave Production and Events Limited | Arts & recreation | 2019 |
| Tide Consulting (IW) Limited | Professional & scientific | 2018 |
| Timeless Associates Limited | Professional & scientific | 1992 |
| TJ Home Renovations Ltd | Real estate | 2025 |
| TJ Property IOW Limited | Administrative & support | 2023 |
| Tlctech Ltd | Information & communication | 2026 |
| Tosb Ltd | Real estate | 2025 |
| Total Trash Limited | Manufacturing | 2025 |
| Town Gauge Limited | Information & communication | 2026 |
| TQA Management Limited | Hospitality | 2022 |
| TQA98 Limited | Hospitality | 2023 |
| Tracware Asset Management Ltd | Manufacturing | 2022 |
| Tracware Limited | Information & communication | 1999 |
| Trade Solutions (IW) Ltd | Construction | 2025 |
| Trafalgar Oak Limited | Real estate | 2023 |
| Trattles and Trattles Limited | Construction | 2017 |
| Travellers Joy Isle of Wight Limited | Hospitality | 2024 |
| Tredegar Court (IOW) Management Company Ltd | Administrative & support | 2026 |
| Triangle Cables (UK) Limited | Manufacturing | 1993 |
| Trisha’S Tasty Kitchen Limited | Hospitality | 2023 |
| Trustmark Driveways Limited | Construction | 2022 |