| ES Cleanze Limited | Administrative & support | 2018 |
| ESP Editorial Services Ltd | Administrative & support | 2023 |
| Estate Xperts Ltd | Real estate | 2018 |
| Estuary View (NW) Ltd | Real estate | 2016 |
| ETW Ltd | Wholesale & retail | 2016 |
| Eurodrive Controls Limited | Extraterritorial | 2011 |
| EV Auto Ltd | Wholesale & retail | 2026 |
| EV Options Limited | Administrative & support | 2013 |
| EV Pro ENG Limited | Professional & scientific | 2019 |
| Evans Automation Limited | Professional & scientific | 2014 |
| Evans Protective Coatings Ltd | Administrative & support | 2017 |
| EVC Pension Trustees Limited | Financial services | 1996 |
| Evelectrifyuk Ltd | Construction | 2020 |
| Evelyn Miriam Ltd | Wholesale & retail | 2026 |
| Event Water Solutions Ltd | Professional & scientific | 2005 |
| Everest Runcorn Limited | Wholesale & retail | 2019 |
| Everhope Homes Limited | Health & social care | 2025 |
| Evesam Electrical Ltd | Construction | 2020 |
| Evexia Occupational Health Ltd | Health & social care | 2025 |
| Evolution Dental Studio Limited | Health & social care | 2008 |
| Evolve Recycle Limited | Water & waste | 2025 |
| Evolve Recycled Products Ltd | Professional & scientific | 2020 |
| Evolve Tyre Recycling Ltd | Water & waste | 2025 |
| Exchange People Limited | Administrative & support | 1997 |
| Exedy Clutch Europe Limited | Wholesale & retail | 1989 |
| Express Transformers and Controls (2015) Limited | Manufacturing | 2015 |
| Eyes Wide Open Clothing Ltd | Wholesale & retail | 2022 |
| Eziulo Ltd | Real estate | 2022 |
| F C E Projects Limited | Construction | 2004 |
| F Cannon Plastering Limited | Construction | 2018 |
| F.B.S. Contracts Limited | Manufacturing | 1987 |
| F.B.S. Holdings (UK) Limited | Administrative & support | 2011 |
| Fabrication Support UK Ltd | Professional & scientific | 2018 |
| Facilities Heating Maintenance Limited | Construction | 2005 |
| Fact Property Maintenance Ltd | Construction | 2023 |
| Fairclough & Co Properties Limited | Real estate | 2020 |
| Fairways Hospitality Group Limited | Hospitality | 2024 |
| Faith's Sandy Lane Ltd | Hospitality | 2026 |
| Fallon Bros Limited | Water & waste | 2011 |
| Fancypants Deals Ltd | Wholesale & retail | 2025 |
| Faraday Wheelchair Innovations Ltd | Manufacturing | 2020 |
| Farm Technology Services Ltd | Information & communication | 2020 |
| Farmacival Limited | Professional & scientific | 2008 |
| Farmers Arms (Gastro) Limited | Hospitality | 2025 |
| Farnan Investments Ltd | Real estate | 2019 |
| Farrow's Heating & Plumbing Ltd | Administrative & support | 2021 |
| Fast & Furious Transport Ltd | Transport & logistics | 2014 |
| FBC Utilities Limited | Administrative & support | 2014 |
| Feather Flag Kingdom Ltd | Wholesale & retail | 2019 |
| Fensure IT Limited | Information & communication | 2015 |
| Ferdy Holdings Limited | Administrative & support | 2023 |
| Festina North Ltd | Wholesale & retail | 2025 |
| Festivalway Fishbar Ltd | Hospitality | 2022 |
| FG Translation Services Limited | Wholesale & retail | 2011 |
| FG Universal Ltd | Construction | 2021 |
| Fhat Ltd | Health & social care | 2021 |
| FHC (Holdings) Limited | Professional & scientific | 1966 |
| Fiamma Fire Protection and Consultancy Limited | Construction | 2019 |
| Fibre & Furnaces Limited | Manufacturing | 1979 |
| Fibre House (Installations) Ltd | Information & communication | 2019 |
| Fibreforce Composites Limited | Manufacturing | 1929 |
| Firehorse Business Services Limited | Professional & scientific | 2009 |
| Firelink Consulting Ltd | Information & communication | 2026 |
| First ACT Arts Limited | Arts & recreation | 2021 |
| First Bakery Limited | Hospitality | 2005 |
| First Page Recruitment Ltd | Administrative & support | 2020 |
| FISH4KNOWLEDGE Limited | Professional & scientific | 2025 |
| Fitzwilton Investments Limited | Financial services | 1990 |
| Fitzwilton Property (U.K.) Limited | Manufacturing | 1987 |
| Flair Consultancy & Accounting Limited | Professional & scientific | 2016 |
| Flaym Fuels Limited | Professional & scientific | 1967 |
| FLB Fire and Security Ltd | Construction | 2023 |
| Flexhold Limited | Professional & scientific | 1963 |
| Flightcare Multiservices UK Limited | Professional & scientific | 1962 |
| Floors and Fabric Cleaning Ltd | Administrative & support | 2025 |
| FLORIN85 Limited | Transport & logistics | 2014 |
| Florite Fittings and Fabrication Limited | Manufacturing | 2005 |
| Flowers of Runcorn Ltd | Wholesale & retail | 2020 |
| FM Joinery Limited | Construction | 2017 |
| Forbes H R Limited | Administrative & support | 2006 |
| Forest Lodges Ltd | Construction | 2017 |
| Forster Dean Ltd | Professional & scientific | 2007 |
| Forster Professional Services Ltd | Professional & scientific | 2016 |
| Fortrustholding Limited | Public administration | 2023 |
| Fortune Properties (North West) Limited | Real estate | 2016 |
| Foss U.K. Limited | Wholesale & retail | 1961 |
| Four Estates Limited | Administrative & support | 1999 |
| Four Rainbows Training Ltd | Education | 2019 |
| Four Seasons Runcorn Limited | Hospitality | 2024 |
| Fourforty Ltd | Administrative & support | 2022 |
| Fourrmula Limited | Professional & scientific | 2018 |
| FOX Controls Limited | Administrative & support | 2014 |
| Fpsai Ltd | Wholesale & retail | 2026 |
| Framecut Limited | Information & communication | 2025 |
| Frank Armitt & SON Limited | Transport & logistics | 1962 |
| Freedom Solutions Ltd | Administrative & support | 2025 |
| Freemon Software Solutions Ltd | Information & communication | 2024 |
| Freeway UK Insurance Services Limited | Financial services | 2000 |
| Fresenius Kabi Limited | Manufacturing | 1987 |
| Fresh Click Limited | Information & communication | 2014 |