| Donvicinocare Ltd | Health & social care | 2020 |
| Dora Property Services Ltd | Real estate | 2025 |
| Doveandlace Limited | Wholesale & retail | 2025 |
| Downdune Trading Limited | Administrative & support | 2021 |
| Drawing and Design Services Ltd | Professional & scientific | 2023 |
| DRG Options Limited | Transport & logistics | 2018 |
| DRG Services Group Ltd | Professional & scientific | 2017 |
| Drive Auto Solutions Ltd | Wholesale & retail | 2025 |
| Drive by ANN Limited | Transport & logistics | 2023 |
| Driversforhire Ltd | Administrative & support | 2025 |
| Drop Chain Limited | Construction | 2023 |
| DRS Edge Limited | Extraterritorial | 2022 |
| DRS Premier Limited | Extraterritorial | 2017 |
| Drs-Uk Limited | Extraterritorial | 2017 |
| DSA Olteanu Ltd | Transport & logistics | 2024 |
| DSL Steelfixing Ltd | Manufacturing | 2014 |
| DSR Tiling Services Ltd | Construction | 2021 |
| DT Smart Access Limited | Professional & scientific | 2017 |
| DTC (North West) Ltd | Professional & scientific | 2020 |
| Dtec Site Services Limited | Extraterritorial | 2015 |
| DTL Machinery UK Limited | Manufacturing | 2023 |
| DUB LUV Supplies Ltd | Wholesale & retail | 2020 |
| Duffy Properties (North West) Ltd | Real estate | 2021 |
| Duhok Plus Ltd | Other services | 2025 |
| Dunne and Dusted Logistics Limited | Other services | 2020 |
| Duxford Consulting Limited | Professional & scientific | 2025 |
| DVR Property Services Limited | Real estate | 2023 |
| DW Storage Ltd | Wholesale & retail | 2024 |
| Dynopro Racing Limited | Wholesale & retail | 2008 |
| E. Basnett Limited | Construction | 1988 |
| E.P.A. (Engineering Purchasing Agents) Ltd | Wholesale & retail | 1999 |
| E.S.L. Electromech Limited | Manufacturing | 2001 |
| Earf Audio Ltd | Wholesale & retail | 2023 |
| Earls Limousines Limited | Transport & logistics | 2006 |
| Easibuy Ltd | Wholesale & retail | 2013 |
| Eastern Chef Asian Cuisine Ltd | Hospitality | 2026 |
| Easy Finance Group Limited | Financial services | 2026 |
| EBL Church Developments Limited | Construction | 2004 |
| EBL Construction Limited | Construction | 2012 |
| EBL Developments Limited | Construction | 2003 |
| EBL Management Services Limited | Real estate | 2008 |
| EBL Modular Limited | Construction | 2005 |
| EBL Waterfront Developments Ltd | Construction | 2006 |
| Echo Care Group Limited | Construction | 2021 |
| Echo Supported Living Services Limited | Health & social care | 2019 |
| Eco Recovery Ltd | Transport & logistics | 2024 |
| Ecological Landscapes Management Limited | Administrative & support | 2012 |
| Eddcon Ltd | Construction | 2018 |
| Edren Services Ltd Ltd | Real estate | 2025 |
| Edwards Grounds Limited | Real estate | 2003 |
| EGB Estates Ltd | Real estate | 2024 |
| Egerton (Gastro) Ltd | Hospitality | 2023 |
| Egpv Ltd | Professional & scientific | 2011 |
| EH4AR Ltd | Wholesale & retail | 2019 |
| Ekvira Tech Ltd | Information & communication | 2026 |
| Elchi Homes Ltd | Real estate | 2024 |
| Elearn Limited | Professional & scientific | 1999 |
| Electric Arts Ltd | Arts & recreation | 2019 |
| Electriceel Creative Limited | Other services | 2019 |
| Electromec Garage Limited | Wholesale & retail | 2023 |
| Elephant Driving Academy Ltd | Education | 2023 |
| Elevate and Empower Care Ltd | Health & social care | 2026 |
| Elevra Limited | Professional & scientific | 2024 |
| ELI Car Service Ltd | Other services | 2018 |
| Elite Edge Sports Ltd | Information & communication | 2026 |
| Elite Tail Lifts Ltd | Manufacturing | 2017 |
| Elizabeth Mitchelle Limited | Other services | 2012 |
| Ellatogether C.I.C. | Arts & recreation | 2010 |
| Ellis Expediting Services Limited | Professional & scientific | 2007 |
| Elysium CNS Ltd | Information & communication | 2020 |
| EMB Electrics Ltd | Extraterritorial | 2021 |
| Embeddeduk Limited | Other services | 2009 |
| Emerald Security Solutions Limited | Administrative & support | 2022 |
| Emergency Safety Solutions Ltd | Professional & scientific | 2022 |
| Emery Mechanical Services Ltd | Construction | 2020 |
| Emilia&Daniel Ltd | Transport & logistics | 2021 |
| Emma Creasey Lettings Limited | Real estate | 2015 |
| Emovis Operations Mersey Ltd | Information & communication | 2008 |
| Enchanted Beauty Ltd. | Other services | 2025 |
| Encore Runcorn Ltd | Hospitality | 2017 |
| Endless Possibilities With CBD Ltd | Wholesale & retail | 2019 |
| Engage Training Academy Ltd | Education | 2020 |
| Engenda Group Limited | Construction | 2009 |
| Engenda Leasing Limited | Administrative & support | 2022 |
| Engenda Limited | Extraterritorial | 1977 |
| Engenda Properties Limited | Real estate | 2014 |
| Engineered Facade Solutions Ltd | Construction | 2022 |
| Enhanced Community Healthcare Options (Echo) Limited | Financial services | 2014 |
| Enos Limited | Information & communication | 2001 |
| Enterprise Business Logistics Ltd | Real estate | 2007 |
| Entire Financial Services Ltd | Financial services | 2025 |
| Entropix Limited | Professional & scientific | 2021 |
| Enviro Energy Ltd | Professional & scientific | 2024 |
| EPC Renewals Ltd | Professional & scientific | 2024 |
| Eponawoodworks Limited | Manufacturing | 2025 |
| Eprocom Limited | Wholesale & retail | 2024 |
| Equity and Grant Limited | Administrative & support | 2008 |
| Equity and Grant Partners Ltd | Professional & scientific | 2014 |
| Equity Release Services Limited | Financial services | 2017 |
| ER System UK Ltd | Wholesale & retail | 2024 |