| Rongzhi Co., Limited | Wholesale & retail | 2024 |
| Roof Cleaners Direct Ltd | Administrative & support | 2024 |
| Roofco Home Improvements (UK) Limited | Construction | 2025 |
| Roofline (London) Limited | Construction | 2022 |
| Roofline Roofing and Guttering Ltd | Construction | 2024 |
| Roots 2 Wellness Nutritional Coaching Ltd | Other services | 2025 |
| Rose Estates PK Ltd | Real estate | 2024 |
| Rose Legal Services Limited | Professional & scientific | 2008 |
| Rosecare Chesterfield Limited | Health & social care | 2016 |
| Rosecare Shirebrook Limited | Health & social care | 2015 |
| Rosecroft Trading Limited | Wholesale & retail | 2016 |
| Rosee Properties Limited | Construction | 2020 |
| Rosegold Official UK Ltd | Extraterritorial | 2021 |
| Rosh & Nosh Ltd | Hospitality | 2025 |
| Ross Maintenance Ltd | Construction | 2014 |
| Rossmere Park Care Centre Limited | Health & social care | 2016 |
| Rotunda Tech Ltd | Wholesale & retail | 2023 |
| Rotunda-Hygeia Ltd | Health & social care | 2019 |
| Route Dynamic Limited | Professional & scientific | 2018 |
| Route Runners Courier Ltd | Transport & logistics | 2026 |
| Routemaster BUS London Ltd | Transport & logistics | 2024 |
| Rovij Training Ltd | Education | 2024 |
| ROW 11 Limited | Professional & scientific | 2022 |
| Rowhill Homes Ltd | Real estate | 2018 |
| Roy's Jamaican Cuisine Limited | Hospitality | 2013 |
| Royale Business College UK Ltd | Education | 2019 |
| RP General Building Ltd | Construction | 2018 |
| RP Health Consultancy Ltd | Administrative & support | 2023 |
| RP Landscape Services Ltd | Administrative & support | 2007 |
| RP Trading Company International Ltd | Wholesale & retail | 2020 |
| RPB Electrical Solutions Ltd | Construction | 2026 |
| Rpmp Group Limited | Financial services | 2025 |
| Rpmp Properties Limited | Real estate | 2026 |
| RPT Networking Limited | Information & communication | 2023 |
| Rraichura Ltd | Professional & scientific | 2021 |
| Rrcp Limited | Information & communication | 2026 |
| RS Barbers Ltd | Other services | 2018 |
| RS Dent Ltd | Health & social care | 2021 |
| RS Designs London Ltd. | Wholesale & retail | 2013 |
| RSA Mechanical Installations Ltd | Construction | 2019 |
| Rsfsoft Ltd | Wholesale & retail | 2020 |
| RSK Burials & Cremations Ltd | Other services | 2025 |
| RSK Funerals Ltd | Other services | 2025 |
| RSK Property Solutions Ltd | Construction | 2021 |
| RSR Pharmacare Limited | Financial services | 2013 |
| RT Management London Ltd | Other services | 2014 |
| RTI Group Services Limited | Construction | 2020 |
| RTR Direct Ltd | Other services | 2020 |
| RUA Legal Ltd | Professional & scientific | 2024 |
| Rubinski Ltd | Professional & scientific | 2020 |
| Ruby Fasteners and Hardware Ltd | Wholesale & retail | 2017 |
| Ruby Heights Ltd | Households | 2024 |
| RUI Valve Industry Co., Ltd | Administrative & support | 2021 |
| Ruilidi Instrument Co., Ltd | Administrative & support | 2021 |
| Ruislip Appliances Limited | Wholesale & retail | 1958 |
| Ruislip Blinds Limited | Manufacturing | 2014 |
| Ruislip Catering Limited | Hospitality | 2014 |
| Ruislip Chippy Ltd | Hospitality | 2022 |
| Ruislip Currency Ltd | Financial services | 2010 |
| Ruislip Developments Ltd | Real estate | 2021 |
| Ruislip Drives and Patios Limited | Construction | 2021 |
| Ruislip Homes Ltd | Real estate | 2026 |
| Ruislip Iproperties Ltd | Real estate | 2024 |
| Ruislip IT Services Limited | Administrative & support | 2015 |
| Ruislip Kebab Ltd | Hospitality | 2017 |
| Ruislip Manor Scissors Hand Ltd | Other services | 2021 |
| Ruislip Manor Sports & Social Club,Limited | Arts & recreation | 1947 |
| Ruislip Marble and Granite Ltd | Construction | 2018 |
| Ruislip Marble Ltd | Construction | 2024 |
| Ruislip Mobile and Vape Ltd | Wholesale & retail | 2025 |
| Ruislip MOT and Services Ltd | Wholesale & retail | 2023 |
| Ruislip Motor Repairs Limited | Wholesale & retail | 2010 |
| Ruislip Plumbing Services Ltd | Construction | 2019 |
| Ruislip Print & Mail Limited | Other services | 2019 |
| Ruislip Real Estate Ltd | Real estate | 2020 |
| Ruislip Stars Holdings Ltd | Education | 2026 |
| Ruislip Stars Nurseries at ST Mary's Ltd | Education | 2022 |
| Ruislip Ventures Ltd | Professional & scientific | 2013 |
| Rumball Electrical Limited | Construction | 2019 |
| Runhang Group Co., Ltd | Wholesale & retail | 2024 |
| Runway Studio Ltd | Information & communication | 2015 |
| Rusheer Ltd | Wholesale & retail | 2020 |
| Russell Carpentry & Building Ltd | Construction | 2018 |
| Russian Dolls Education Centre Limited | Education | 2017 |
| Ruthtop Properties Ltd | Real estate | 2020 |
| Ryan Contractors Ltd | Construction | 2021 |
| Rykie Properties Ltd | Real estate | 2017 |
| RYP Holdings Limited | Real estate | 2018 |
| Ryple Ltd | Education | 2024 |
| RZ Pro-Management Limited | Other services | 2014 |
| S & M DRY Cleaner Limited | Other services | 2018 |
| S & N London Holdings Ltd | Real estate | 2024 |
| S & S Flooring Solutions Limited | Construction | 2018 |
| S Alan Engineering Ltd | Manufacturing | 2024 |
| S Disney Limited | Manufacturing | 2007 |
| S H L Property Services Ltd | Construction | 2012 |
| S K Enterprises South Limited | Administrative & support | 2013 |
| S K Painting Ltd | Construction | 2015 |
| S K S UK Limited | Wholesale & retail | 2008 |
| S L R Lighting Services Ltd | Construction | 2024 |