| Stepnell Group Limited | Financial services | 2024 |
| Stepping OUT Theatre Rugby Limited | Arts & recreation | 2022 |
| Stepsmith Ltd | Wholesale & retail | 2019 |
| Sterling (EC) Limited | Other services | 1990 |
| Sterling High Financial Solutions Ltd | Professional & scientific | 2019 |
| Sternfenster Commercial LLP | | 2024 |
| Sternfenster Timber LLP | | 2024 |
| Steve Cane Carpets Ltd | Construction | 2024 |
| Steve Heath Ltd | Other services | 2021 |
| Steve Kinder Limited | Transport & logistics | 2010 |
| Steve's Ventures Limited | Wholesale & retail | 2025 |
| Stewart Taylor Generator Specialist Limited | Manufacturing | 2011 |
| Still Maame YAA Company Limited | Other services | 2023 |
| Stillwork Limited | Real estate | 1999 |
| Stinger Creations Ltd | Arts & recreation | 2025 |
| Stitched Studio Rugby Ltd | Wholesale & retail | 2026 |
| Stkd Martial Arts LLP | | 2019 |
| STM Contracts LLP | | 2012 |
| STM Transport Limited | Transport & logistics | 2012 |
| Stocks Industrial Limited | Real estate | 2025 |
| Stocks Rentals Limited | Real estate | 2025 |
| Stocks Services Limited | Administrative & support | 2019 |
| Stoica V-Trade Ltd | Transport & logistics | 2017 |
| Stoke Park Consulting Ltd | Professional & scientific | 2018 |
| Stokrotka Rugby Ltd | Wholesale & retail | 2018 |
| Stonara Property Investments Limited | Real estate | 2025 |
| Stone Bench Properties Ltd | Real estate | 2026 |
| Stonehouse Salon & Spa Ltd | Other services | 2017 |
| Stonewall Response Limited | Administrative & support | 2011 |
| Stonewall Security Ltd | Administrative & support | 2008 |
| Stonewall Vaults Limited | Transport & logistics | 2021 |
| Storage & Removal Boxes Limited | Administrative & support | 2016 |
| Storage Solutions Rugby Ltd | Professional & scientific | 2007 |
| Storage World Dunchurch Limited | Transport & logistics | 2017 |
| Storers (Surveyors) Limited | Professional & scientific | 2011 |
| Stormshield Limited | Construction | 2025 |
| Strachan Sports Consultancy Limited | Arts & recreation | 2020 |
| Straight Mile Ltd | Professional & scientific | 2021 |
| Straight Talking People Ltd | Professional & scientific | 2011 |
| Strange & Charmed Productions Ltd | Information & communication | 2026 |
| Stratacomp Ltd | Wholesale & retail | 2024 |
| Strataven Consulting Ltd | Professional & scientific | 2025 |
| Strategic Measures Consultancy Ltd | Professional & scientific | 2021 |
| Streetwood Limited | Professional & scientific | 2017 |
| Stresses to Smiles for Schools Limited | Education | 2021 |
| Stresses to Smiles Limited | Education | 2021 |
| Stretton Consulting Ltd | Professional & scientific | 2013 |
| Stretton Investment Group Limited | Professional & scientific | 2024 |
| Stretton Spreading Limited | Agriculture & fishing | 2016 |
| Strettons Spreading Services Ltd | Agriculture & fishing | 2002 |
| Strides Footwear Limited | Wholesale & retail | 2024 |
| Stripeika Trans Ltd | Transport & logistics | 2017 |
| Stripey Enid Limited | Wholesale & retail | 2014 |
| Strong Double Glazing Ltd. | Construction | 2023 |
| Studio Bandit Ltd | Professional & scientific | 2026 |
| Studio Timber Limited | Wholesale & retail | 2025 |
| Studiokazaad Ltd | Professional & scientific | 2024 |
| Stuff 13 Limited | Information & communication | 2007 |
| Stuvic Limited | Manufacturing | 2007 |
| Success Logistics Ltd | Transport & logistics | 2020 |
| Successful 88 Limited | Hospitality | 2026 |
| Sultan Spices Limited | Hospitality | 2018 |
| Sultan Turkish Limited | Hospitality | 2019 |
| Summers Trading Ltd | Wholesale & retail | 2023 |
| Summit Trades Limited | Construction | 2025 |
| Summit Transformation Ltd | Professional & scientific | 2021 |
| Sun and Moon Investments Limited | Real estate | 2020 |
| Sunborough Group Ltd | Wholesale & retail | 2025 |
| Sunday Riders Cult Ltd | Wholesale & retail | 2025 |
| Sunflower BG Limited | Construction | 2011 |
| Sunflowers Nurseries Limited | Education | 2000 |
| Sunnah Price Ltd | Wholesale & retail | 2024 |
| Sunny Weather Ltd | Construction | 2023 |
| Sunrise Contractors Limited | Construction | 2022 |
| Sunshing Cuisine Limited | Hospitality | 2025 |
| Sunshyne Limited | Transport & logistics | 2016 |
| Sunstone Project Consultants Ltd | Professional & scientific | 2025 |
| Sunway South Yorkshire Limited | Real estate | 2021 |
| Super KIT AI Ltd | Information & communication | 2024 |
| Superb M Ltd | Transport & logistics | 2026 |
| Superhands Ltd | Other services | 2018 |
| Supermodels Ltd | Wholesale & retail | 2024 |
| Supply Point Systems Limited | Manufacturing | 1998 |
| Supply Supply Limited | Education | 2006 |
| Support 121 Ltd | Transport & logistics | 2012 |
| Supportive Learning CIC | Education | 2018 |
| Surecare Rugby & North Warwickshire Limited | Health & social care | 2016 |
| Surecraft Home Improvements Ltd | Construction | 2024 |
| Surespace Limited | Administrative & support | 2021 |
| Surfaces R US Limited | Water & waste | 2017 |
| Surgicert UK LLP | | 2020 |
| Surmah Co Ltd | Hospitality | 2019 |
| Surrealz Ltd | Wholesale & retail | 2015 |
| Surrey Investments Limited | Real estate | 1918 |
| Susa (2017) Limited | Other services | 2017 |
| SV Development & Lettings Ltd | Real estate | 2019 |
| SVS Civils LLP | | 2016 |
| SVS Food and Wine Ltd | Wholesale & retail | 2024 |
| SVS Technologies Group Limited | Information & communication | 2020 |
| Swallow and Company (Northampton) Limited | Professional & scientific | 2007 |