| Dyce Utilities Limited | Energy | 2019 |
| Dylan Homes Ltd | Real estate | 2019 |
| Dynamic DIE and Steel (Sheffield) Limited | Construction | 2020 |
| Dynamic Electronic Security Ltd | Administrative & support | 2018 |
| Dynamical Developments Ltd | Construction | 2016 |
| Dynamo Solution Limited | Wholesale & retail | 2025 |
| E & F Plumbing Contractors Limited | Extraterritorial | 2004 |
| E B Automation Ltd. | Information & communication | 2007 |
| E B Logistics Limited | Transport & logistics | 2024 |
| E Breaker Limited | Wholesale & retail | 2022 |
| E G H Group Ltd | Financial services | 2026 |
| E&C Crane Engineering Limited | Extraterritorial | 2014 |
| E&J's Kitchen Limited | Hospitality | 2026 |
| E&M Distributions Ltd | Wholesale & retail | 2023 |
| E&M Plastering Services Ltd | Construction | 2025 |
| E&N Taxi Service Ltd | Transport & logistics | 2024 |
| E&S Hottrade Ltd | Wholesale & retail | 2015 |
| E'Media Brand Design Limited | Administrative & support | 2010 |
| E-Kaliteri Ltd | Administrative & support | 2015 |
| E. L. Stokes Educational Psychologist Ltd | Education | 2023 |
| E. Lloyd & SON Limited | Professional & scientific | 1987 |
| E.D.S. Civils Limited | Construction | 2019 |
| E.R.I Truck BUS & Plant Ltd | Wholesale & retail | 2024 |
| E.Russum & Sons,Limited | Manufacturing | 1906 |
| E.T Pipework Services Ltd | Construction | 2021 |
| E3 Accountancy Ltd | Professional & scientific | 2025 |
| EA Car Group Ltd | Wholesale & retail | 2026 |
| EAG Cladding Systems Limited | Construction | 2019 |
| EAG Facilities & Cleaning Services Ltd | Administrative & support | 2025 |
| EAM Construction Ltd | Construction | 2026 |
| EAR Specialists (AA) Ltd | Health & social care | 2022 |
| Earl Holdings Ltd | Financial services | 2022 |
| Earl Robinson Limited | Other services | 2019 |
| Earned Beer Ltd | Wholesale & retail | 2023 |
| Earnshaw Electrical Services Limited | Construction | 2025 |
| Earnwulf Windows Ltd | Construction | 2025 |
| Earth Escapes Ltd | Administrative & support | 2026 |
| Easi-Keg Solutions Ltd | Manufacturing | 2022 |
| Easi-Mix Systems Ltd | Professional & scientific | 2020 |
| East Dragon City Ltd | Hospitality | 2017 |
| East Mini Market Ltd | Wholesale & retail | 2026 |
| East Partners Ltd | Arts & recreation | 2025 |
| Eastdene Invest Ltd | Real estate | 2025 |
| Eastern Motor Sales Ltd | Wholesale & retail | 2025 |
| Eastmills Finance Limited | Administrative & support | 1993 |
| Eastwood and Savage Properties Limited | Real estate | 2020 |
| Eastwood and Savage Renovations Limited | Real estate | 2023 |
| Eastwood Autos Ltd | Wholesale & retail | 2019 |
| Eastwood Domestics (Rotherham) Ltd | Wholesale & retail | 2019 |
| Eastwood Industrial Access Ltd | Professional & scientific | 2025 |
| Eastwood Welding Ltd | Manufacturing | 2024 |
| Easy Motor Finance Limited | Wholesale & retail | 2012 |
| EAT Different Limited | Hospitality | 2015 |
| EAT the Country Ltd | Hospitality | 2023 |
| Eaton Commercial Management Limited | Extraterritorial | 2016 |
| Eaton Commercial Property Consultants Limited | Professional & scientific | 2010 |
| EAZ Limited | Administrative & support | 2017 |
| Eazy Hire Ltd | Administrative & support | 2017 |
| Eazycars Ltd | Wholesale & retail | 2023 |
| Eazzy Buy Ltd | Wholesale & retail | 2021 |
| Ebonyomakeup Ltd | Other services | 2022 |
| EC Tech Supply Limited | Wholesale & retail | 2025 |
| Eccounting UK Limited | Professional & scientific | 2026 |
| ECE Expert Care Ltd | Health & social care | 2022 |
| Echo and Bloom Ltd | Wholesale & retail | 2025 |
| Echo Athletics Ltd | Education | 2023 |
| Echo SP UK Ltd | Professional & scientific | 2021 |
| ECHO1867 Limited | Arts & recreation | 2025 |
| Eclectic Property Investment Limited | Real estate | 2018 |
| Eco Exterior Limited | Construction | 2023 |
| Eco GAS Services Ltd | Construction | 2007 |
| Eco Heat Surge (Yorkshire) Limited | Construction | 2025 |
| Eco Infinity Ltd | Administrative & support | 2017 |
| Eco Mechanical Building Limited | Construction | 2020 |
| Eco Prestige Property Ltd | Real estate | 2026 |
| Eco Ventilation Ltd | Administrative & support | 2020 |
| Eco-Pro Facility Management Ltd | Administrative & support | 2025 |
| Ecode Group Ltd | Information & communication | 2017 |
| Ecodriuk Ltd | Manufacturing | 2019 |
| Ecom Revolution Ltd | Education | 2023 |
| Ecomar Logistics Limited | Transport & logistics | 2019 |
| Ecosheff Ltd | Construction | 2025 |
| Ecospill Group Holdings Limited | Financial services | 2022 |
| Ecospill Ltd | Administrative & support | 2010 |
| ED International Limited | Professional & scientific | 2017 |
| Edanny Ltd | Transport & logistics | 2019 |
| Eddleston Rendering Specialist Limited | Construction | 2026 |
| Eden Brickwork Limited | Construction | 2014 |
| Eden Memorials Ltd | Wholesale & retail | 2013 |
| Eden Washroom and Hygiene Services Limited | Administrative & support | 2005 |
| Edenthorpe Grove Limited | Real estate | 2020 |
| Edge Confectionery Limited | Other services | 2008 |
| Edge Fashion Europe Ltd | Wholesale & retail | 2023 |
| Edge Football Stats Limited | Information & communication | 2019 |
| EDGE2EDGE Interior Solutions Ltd | Construction | 2023 |
| Edingale Consulting Ltd | Information & communication | 2022 |
| Edit Academy Ltd | Education | 2022 |
| Edit Aesthetics Clinic Ltd | Other services | 2025 |
| Edr&Medeso Ltd | Information & communication | 2017 |
| Educaid Personnel Limited | Education | 2023 |