| DPK Services Limited | Real estate | 2025 |
| DR a L Baldwin Ltd | Health & social care | 2023 |
| DR G Health Clinic Ltd | Health & social care | 2018 |
| DR Haneen Aesthetics Ltd | Other services | 2024 |
| DR M Ditta Limited | Health & social care | 2015 |
| DR Nate Shearman Ltd | Health & social care | 2021 |
| DR Plastering Ltd | Construction | 2019 |
| DR Sham Medical Services Limited | Administrative & support | 2016 |
| DR Supply Chain Ltd | Professional & scientific | 2021 |
| DR. Gabriela Aguilar Medical Aesthetics Limited | Health & social care | 2018 |
| Dr.S.Nawaz Limited | Health & social care | 2011 |
| DR1VE Ltd | Transport & logistics | 2025 |
| Drab Yorkshire Ltd | Hospitality | 2023 |
| Draft-Tec Ltd | Professional & scientific | 2022 |
| Dragon Rigging Limited | Information & communication | 2020 |
| Dragu Ltd | Wholesale & retail | 2023 |
| Draper Greyhounds Ltd | Other services | 2026 |
| Draper Racing Limited | Arts & recreation | 2026 |
| Drawing Baud Limited | Information & communication | 2015 |
| Drawmer Electronics Limited | Manufacturing | 1983 |
| Draycott Roofing Limited | Construction | 2017 |
| Draz Limited | Real estate | 2021 |
| DRC Airbag Suits Ltd | Manufacturing | 2024 |
| Dream Divers Ltd | Arts & recreation | 2006 |
| Dream Drive Autos Limited | Wholesale & retail | 2025 |
| Dream Money Limited | Financial services | 2008 |
| Dreambook Ltd | Professional & scientific | 2024 |
| Dreamsync Network Ltd | Wholesale & retail | 2021 |
| Dreamtobelive Ltd | Wholesale & retail | 2023 |
| Dreamy Doze Ltd | Wholesale & retail | 2025 |
| Drill-Equip Limited | Construction | 2020 |
| Drim Speed Ltd | Transport & logistics | 2019 |
| Drimee Limited | Manufacturing | 2014 |
| Dripuk Limited | Hospitality | 2021 |
| Drive Master (South Yorkshire) Limited | Administrative & support | 2024 |
| Drive With AAA Ltd | Education | 2026 |
| Drivecourt (CV) Ltd | Wholesale & retail | 2024 |
| Driveways Rotherham Ltd | Administrative & support | 2026 |
| Drivewise Automotive Ltd | Wholesale & retail | 2023 |
| Drivva Ltd | Administrative & support | 2025 |
| DRMICH13 Limited | Health & social care | 2022 |
| Drobe Services Limited | Administrative & support | 2007 |
| Drobvlad Ltd | Transport & logistics | 2019 |
| Drone Tech Education Limited | Education | 2025 |
| Dronevision AI UK Ltd | Construction | 2026 |
| Dronfield Healthcare Limited | Wholesale & retail | 2023 |
| Dropzone Corp Ltd | Wholesale & retail | 2025 |
| Drtyco Ltd | Wholesale & retail | 2017 |
| Drunken Goose Ltd | Hospitality | 2024 |
| Drury & Co Limited | Extraterritorial | 2010 |
| Drywall Partitions & Ceilings Ltd | Construction | 2019 |
| DS Driving School Ltd | Education | 2021 |
| DS Estate Wakefield Ltd | Wholesale & retail | 2025 |
| DS MOT Station Limited | Wholesale & retail | 2012 |
| DS Plumbing and Heating Services Ltd | Construction | 2020 |
| Ds.Van Ltd | Transport & logistics | 2025 |
| DSC Commercial Holdings Limited | Financial services | 2023 |
| DSC Commercial Limited | Professional & scientific | 2015 |
| DSH Surveying Limited | Construction | 2014 |
| Dshah Limited | Health & social care | 2013 |
| Dsimps Ltd | Financial services | 2024 |
| DSJ Investments Limited | Real estate | 2022 |
| Dsmc Car Sales Ltd | Wholesale & retail | 2021 |
| Dsmc Property Rentals Ltd | Real estate | 2023 |
| Dsmc Salvage Ltd | Wholesale & retail | 2020 |
| Dssg Holdings Ltd | Real estate | 2021 |
| DST Logistics Ltd | Administrative & support | 2018 |
| DSW Specialised Courier Ltd | Transport & logistics | 2026 |
| DT Joinery (Yorkshire) Limited | Construction | 2024 |
| DT Powell Motors Ltd | Wholesale & retail | 2023 |
| DT Roth Ltd | Hospitality | 2024 |
| DT Stays Limited | Real estate | 2024 |
| DTS Plumbing & Heating Services Ltd | Construction | 2016 |
| Dual-Air Limited | Construction | 2013 |
| Dube Fitness Services Ltd | Arts & recreation | 2023 |
| Duce Business and Project Management Services Ltd | Professional & scientific | 2016 |
| Duckworth Developments Ltd | Construction | 2025 |
| Dudek Trading Ltd | Construction | 2023 |
| Dudley & Sons Roofing Ltd | Construction | 2021 |
| Duffy & Co Limited | Professional & scientific | 2011 |
| Dunk Bridge Ltd | Professional & scientific | 2025 |
| Dunlop Healthcare Services Ltd | Information & communication | 2025 |
| Dunmi Limited | Hospitality | 2025 |
| Dunn Holdings Limited | Financial services | 2022 |
| Dunwood Management Company Limited | Households | 2023 |
| Duodynamic Safety Solutions Ltd | Professional & scientific | 2024 |
| Duplicity Clothing Ltd | Wholesale & retail | 2023 |
| Dutchcon Engineering (UK) Limited | Manufacturing | 2020 |
| Dutko Group Ltd | Information & communication | 2013 |
| Dutton Construction Ltd | Construction | 2016 |
| Dutton FM Limited | Administrative & support | 2022 |
| Duudl Ltd | Arts & recreation | 2016 |
| DW Drywall Limited | Construction | 2025 |
| DW Plastering Ltd | Construction | 2021 |
| Dwmr Ltd | Transport & logistics | 2025 |
| Dyce Energy Electricity Ltd | Energy | 2024 |
| Dyce Energy GAS Ltd | Energy | 2024 |
| Dyce Energy Group Limited | Financial services | 2017 |
| Dyce Energy Limited | Energy | 2016 |
| Dyce Properties Limited | Construction | 2021 |