| Shanaghy Engineering Services Ltd | Administrative & support | 2016 |
| Shanaishwar Ltd | Other services | 2025 |
| Shanapro Limited | Health & social care | 2023 |
| Shanel Management Ltd | Other services | 2024 |
| Shangolis Investments Ltd | Extraterritorial | 2007 |
| Shangri-La Retreat Ltd | Other services | 2024 |
| Shann Accountancy and Financial Services Ltd | Professional & scientific | 2020 |
| Shanti Queens Road Ltd | Hospitality | 2011 |
| Shape Fitness UK Limited | Arts & recreation | 2021 |
| Sharada Bhakta Ltd | Real estate | 2025 |
| Shard Productions Ltd | Information & communication | 2024 |
| Sharewood Homes Ltd | Real estate | 2024 |
| Sharky & Claws Properties Ltd | Real estate | 2018 |
| Sharleen's Beauty Therapy Limited | Other services | 2026 |
| Sharma Construction Limited | Construction | 2025 |
| Sharon Toulson - the Able PA Limited | Households | 2025 |
| Sharpeline Ltd | Wholesale & retail | 2024 |
| Sharwood Electrical and Fire Ltd | Construction | 2021 |
| SHASS5 Construction Ltd | Construction | 2018 |
| Shavga Construction Ltd | Construction | 2019 |
| Shaw Creative Ltd | Professional & scientific | 2020 |
| Shawarch Limited | Construction | 2019 |
| SHAYA78 Limited | Health & social care | 2022 |
| SHE CAN Play Football Club Ltd | Arts & recreation | 2024 |
| Shear Excellence Garden Services Limited | Administrative & support | 2021 |
| Shear's Perception Ltd | Other services | 2023 |
| Shearwater Drainage Services Limited | Construction | 1995 |
| Shecorp Ltd | Information & communication | 2025 |
| Sheer London Limited | Wholesale & retail | 2018 |
| Shefa Associates Ltd | Health & social care | 2020 |
| Sheharyar Event Management Limited | Hospitality | 2020 |
| Shehi Interiors Ltd | Construction | 2017 |
| Sheikh Films Ltd | Information & communication | 2024 |
| Shekinah Support Ltd | Health & social care | 2018 |
| Shel Activities CIC | Education | 2023 |
| Shelby London Limited | Financial services | 2019 |
| Shellb Ltd | Other services | 2025 |
| Shellness Retreat Ltd | Hospitality | 2019 |
| Shelters Property Management Limited | Real estate | 2024 |
| Shelvey Haulage Limited | Administrative & support | 1998 |
| Sheng YU Ltd | Hospitality | 2016 |
| Shepreneurs 4 Education Ltd | Education | 2023 |
| Sher Enterprise Limited | Professional & scientific | 2014 |
| Shere Offices Ltd | Real estate | 2024 |
| Shero Talent Consultancy Ltd | Administrative & support | 2019 |
| Shesam Ltd | Wholesale & retail | 2025 |
| Shield Financial Ltd | Other services | 2017 |
| Shield Roofing and Home Improvements Ltd | Construction | 2025 |
| Shield Skills College Ltd | Administrative & support | 2021 |
| Shiloz Services Limited | Health & social care | 2014 |
| Shimmer Services Ltd | Administrative & support | 2022 |
| Shinar Jewels Limited | Manufacturing | 2016 |
| Shind's Naan Stop Indian Street Food Ltd | Wholesale & retail | 2024 |
| Shine Home Developers Limited | Construction | 2023 |
| Shine-Mart Limited | Wholesale & retail | 2005 |
| Shinemart Group Limited | Administrative & support | 2013 |
| Shining Clarity Limited | Wholesale & retail | 2025 |
| Shining Hearts Care Ltd | Health & social care | 2026 |
| Shining Star Security Ltd | Administrative & support | 2025 |
| Shinkyu MA Equipment Limited | Wholesale & retail | 2020 |
| Shipgo Ltd | Transport & logistics | 2025 |
| Shipit Logistics Ltd | Wholesale & retail | 2021 |
| Shipping Express Limited | Transport & logistics | 2025 |
| Shireeens. Ltd | Professional & scientific | 2025 |
| Shireen Transport Ltd | Transport & logistics | 2020 |
| Shirley Consulting Services Limited | Information & communication | 2015 |
| Shiuka Ltd | Manufacturing | 2025 |
| Shiv Mart Limited | Wholesale & retail | 2025 |
| Shiv Parivar Ltd | Wholesale & retail | 2024 |
| Shiva Builds Ltd | Manufacturing | 2024 |
| Shiva International Limited | Other services | 2025 |
| Shiva Tradings Ltd | Wholesale & retail | 2024 |
| Shivraksha Limited | Real estate | 2021 |
| SHO and Tell Ltd | Education | 2024 |
| Shoe Lane Chambers Limited | Administrative & support | 2021 |
| Shoe Shop & More Limited | Wholesale & retail | 2022 |
| Shoecrazy Limited | Professional & scientific | 1994 |
| Shoes & General Recycling Ltd | Wholesale & retail | 2014 |
| Shols Enterprise Ltd | Administrative & support | 2022 |
| Shooting Sports Shop Limited | Arts & recreation | 2025 |
| Shop Fittings Retail Ltd | Wholesale & retail | 2024 |
| Shop N Save Limited | Wholesale & retail | 2020 |
| Shop Stop Ltd | Wholesale & retail | 2024 |
| Shopbee Ltd | Wholesale & retail | 2025 |
| Shopen Ltd | Construction | 2025 |
| Shopfitpro Limited | Construction | 2024 |
| Shopglobe Limited | Wholesale & retail | 2017 |
| Shopirox Ltd | Wholesale & retail | 2025 |
| Shoplio Ltd | Wholesale & retail | 2025 |
| Shoply Limited | Wholesale & retail | 2021 |
| Shopp Hub Limited | Wholesale & retail | 2025 |
| Shoppe Online Ltd | Wholesale & retail | 2020 |
| Shopuraz Limited | Wholesale & retail | 2025 |
| Shopwhizzu Ltd | Other services | 2013 |
| Shoulda Woulda Coulda Limited | Professional & scientific | 2026 |
| Shree SAI Assets Ltd | Real estate | 2025 |
| Shree SAI Investments Ltd | Real estate | 2024 |
| Shree SAI Supermarket Limited | Wholesale & retail | 2021 |
| Shree Shayam Properties Development Limited | Real estate | 2025 |
| Shreeji Capital Limited | Real estate | 2025 |