| Sterling Gardens (Four) Management Company Limited | Households | 1991 |
| Steve Scaffolding (Kent) Ltd | Construction | 2015 |
| Steve's Aerial Services Ltd | Construction | 2025 |
| Stevos Optimum Services Ltd | Real estate | 2021 |
| Stewart Chester Management Limited | Construction | 2019 |
| Stig Properties (Kent) LLP | | 2021 |
| Stilebridge Holdings Limited | Financial services | 2016 |
| Stiledshuttersandblinds Ltd | Other services | 2024 |
| Stiles Bespoke Glazing Limited | Construction | 2016 |
| Stirling Park Property Limited | Real estate | 2016 |
| Stirling Secretarial Services Limited | Administrative & support | 2000 |
| Stix Consultancy Ltd | Professional & scientific | 2019 |
| Stockland Enterprises Limited | Wholesale & retail | 2024 |
| Stokoeventures Limited | Manufacturing | 2023 |
| Stone Electrical Services Limited | Construction | 2015 |
| Stone Horse Higham Limited | Hospitality | 2014 |
| Stone Photography Ltd | Professional & scientific | 2015 |
| Stone Smyths Limited | Manufacturing | 2023 |
| Stonedale Cottages Ltd | Real estate | 2021 |
| Stoneman Utilities Ltd | Professional & scientific | 2019 |
| Stoneoak Property Ltd | Construction | 2020 |
| Stop Slip Limited | Administrative & support | 2006 |
| STP Accounts Ltd | Professional & scientific | 2025 |
| Straight Line Media Ltd | Information & communication | 2022 |
| Strata Construction Group Limited | Construction | 2009 |
| Strata Contracts Limited | Construction | 2007 |
| Strata Fire Limited | Public administration | 2022 |
| Strata Maintenance Limited | Construction | 2009 |
| Strata Project Services Limited | Construction | 2010 |
| Strata Property and Development Limited | Construction | 2020 |
| Strata Services Group Limited | Financial services | 2020 |
| Strategic Commercial Solutions Limited | Professional & scientific | 2016 |
| Strategy Scaffolding Limited | Construction | 2025 |
| Stratosphere Industries Ltd | Real estate | 2024 |
| Stratta Building Services Ltd | Construction | 2026 |
| Stratta Communications Limited | Information & communication | 2020 |
| Stratta Services Ltd | Professional & scientific | 2020 |
| Streaming Talent Limited | Administrative & support | 2021 |
| Street Associates Limited | Professional & scientific | 2005 |
| Street Light Pubs Ltd | Hospitality | 2024 |
| Streetsestatesholdings Limited | Real estate | 2025 |
| Strike LAB Golf Ltd | Arts & recreation | 2026 |
| Strong Tower Chapel | Other services | 2022 |
| Strood Best Pizza Ltd | Hospitality | 2025 |
| Strood Computers Ltd | Wholesale & retail | 2020 |
| Strood Flamers Ltd | Hospitality | 2024 |
| Strood Flooring Ltd | Wholesale & retail | 2015 |
| Strood Marina Limited | Extraterritorial | 2010 |
| Strood Motor Centre Limited | Wholesale & retail | 2012 |
| Structural Bearings Ltd | Extraterritorial | 2021 |
| STS Plant Hire Ltd | Administrative & support | 2011 |
| Stts Improvements Ltd | Wholesale & retail | 2012 |
| Stuart Jones Hplc Academy Ltd | Education | 2011 |
| Studio 114. Ltd | Other services | 2024 |
| Studs Enterprise Limited | Information & communication | 2025 |
| Study Ahead Ltd | Professional & scientific | 2026 |
| Sturdee Limited | Hospitality | 2020 |
| Subsidence Care Ltd | Other services | 2024 |
| Sucklifts Limited | Professional & scientific | 1990 |
| Sukiglam Shoes Ltd | Wholesale & retail | 2022 |
| Sullivan Residential Ltd | Real estate | 2024 |
| Sullivans Builders Limited | Construction | 2001 |
| Sully NO1 Scaffolding Services Ltd | Construction | 2025 |
| Sully's Scaffolding Solutions Ltd | Construction | 2025 |
| Summerz Taverns Ltd | Hospitality | 2026 |
| Summit Golf UK Ltd | Construction | 2020 |
| Sun Contacts Limited | Wholesale & retail | 2004 |
| Sun Sea and Sand LLP | | 2025 |
| Sunburn Studios Ltd | Administrative & support | 2022 |
| Sunderland Close RTM Company Limited | Real estate | 2011 |
| Sunderland Quay Limited | Real estate | 2025 |
| Sunflower Homes Limited | Real estate | 2020 |
| Sunlight Building Solutions Ltd | Construction | 2022 |
| Sunlight Windows (South East) Ltd | Construction | 2018 |
| Sunord Jewelry & Minerals Limited | Manufacturing | 2025 |
| Sunroot Wholesale Foods Ltd | Wholesale & retail | 2025 |
| Sunset Leisure Ltd | Hospitality | 2026 |
| Sunshine Energy Solutions Ltd | Construction | 2021 |
| Sunshine Lettings (Kent) Ltd | Real estate | 2026 |
| Supersagar Ltd | Real estate | 2020 |
| Supersagar Pictures Ltd | Extraterritorial | 2023 |
| Superstar Shoes Limited | Wholesale & retail | 2012 |
| Support by Mcneils Limited | Health & social care | 2025 |
| Support the Cause Ltd | Other services | 2024 |
| Supreme Building Services Limited | Construction | 2016 |
| Supreme Business Advisory Limited | Professional & scientific | 2026 |
| Supreme Eco Services Ltd | Other services | 2023 |
| Supreme Flooring Limited | Construction | 2008 |
| Supreme Trade Solution & Services Ltd | Construction | 2023 |
| Surf Street Limited | Wholesale & retail | 2013 |
| Sus-Foods Global Ltd | Manufacturing | 2021 |
| Suspended Access Systems Limited | Construction | 1981 |
| Sussex Civils Ltd | Construction | 2024 |
| Sustaina Ltd | Professional & scientific | 2006 |
| Sustainable Garden Solutions Ltd | Administrative & support | 2019 |
| Sustantivo Ltd | Information & communication | 2011 |
| Sutherlands Construction Limited | Construction | 2006 |
| Suzanne Mazeau Ltd | Professional & scientific | 2020 |
| Svans Limited | Wholesale & retail | 2022 |
| SW Consultants Ltd | Professional & scientific | 2025 |