| SRB Plant Hire Limited | Transport & logistics | 2008 |
| Srinikaadvaith Ltd | Other services | 2023 |
| SRS Remedial Solutions Ltd | Construction | 2018 |
| SRS Solutions Limited | Information & communication | 2005 |
| SS & Co Properties Ltd | Real estate | 2026 |
| SS 3D LAB Ltd | Manufacturing | 2026 |
| SS Development Solutions Ltd | Administrative & support | 2021 |
| SS Medical Holdings Limited | Financial services | 2021 |
| SSH1 Commercial Limited | Real estate | 2025 |
| SSH1 Limited | Real estate | 2020 |
| SSJ Care Ltd | Health & social care | 2017 |
| SSY Enterprises Ltd | Wholesale & retail | 2022 |
| ST Clements Court Owners RTM Company Limited | Households | 2017 |
| ST Vincent's R.C. Pre-School Group Community Interest Company | Education | 2015 |
| ST. George Financial Services Limited | Financial services | 2011 |
| Stady Properties Ltd | Construction | 2026 |
| Stagecraft Projects CIC | Information & communication | 2026 |
| Stainless Resources Ltd | Health & social care | 2017 |
| STAIRWAY2STORAGE Ltd | Construction | 2021 |
| Stak-Uk Ltd | Wholesale & retail | 2022 |
| Stamford Risk Consulting Ltd | Administrative & support | 2009 |
| Stamp Investments Ltd | Administrative & support | 2023 |
| Stamp Saver INV Ltd | Professional & scientific | 2025 |
| Standing Services Ltd | Wholesale & retail | 2024 |
| Standith Properties Ltd | Real estate | 2026 |
| Star Linen PVT Ltd | Other services | 2022 |
| Star Media One Limited | Administrative & support | 2013 |
| Starlight Customs Ltd | Wholesale & retail | 2024 |
| Stars Transfer & Transport Ltd | Transport & logistics | 2025 |
| Start Rebuild Ltd | Construction | 2025 |
| Starterworld Ltd | Real estate | 2026 |
| Statley Holmes Limited | Construction | 2018 |
| Statusgain Limited | Real estate | 1996 |
| Stauf Adhesives UK Limited | Manufacturing | 2014 |
| Staynova Properties Ltd | Real estate | 2026 |
| Steadwell Consulting Limited | Wholesale & retail | 2025 |
| Stellata Management Limited | Real estate | 2021 |
| Stelynn Haulage Contractors Limited | Transport & logistics | 2015 |
| Stephandavid Enterprise Ltd | Wholesale & retail | 2026 |
| Stephen a. Leach Ltd | Extraterritorial | 2014 |
| Stephen Bleakley Management Ltd | Administrative & support | 2015 |
| Stephen Heywood Automobile Engineers Limited | Administrative & support | 2001 |
| Stephen MEE Productions Ltd | Information & communication | 2024 |
| Stephen Palmer Investments Limited | Real estate | 2017 |
| Stephenson Developments (Bradford) Ltd | Construction | 2019 |
| Steplin Mechanical Design Ltd | Professional & scientific | 2019 |
| Steps Shoes Limited | Wholesale & retail | 2012 |
| Steps to Success Tuition Centre CIC | Education | 2026 |
| Stepway Property Renovation Limited | Construction | 2026 |
| Sterling Bean Limited | Administrative & support | 2020 |
| Sterling Property and Management Ltd | Real estate | 2023 |
| Sterling Restorations Ltd | Construction | 2021 |
| Sterling Surface Solutions Limited | Administrative & support | 2026 |
| Stert Limited | Real estate | 2025 |
| Steve Lomax Mortgages and Financial Services Ltd | Administrative & support | 2005 |
| Steve Mitchell Decorating Limited | Construction | 2013 |
| Steve Parker's Service & Repair Ltd | Wholesale & retail | 2016 |
| Stitched-In Ltd | Wholesale & retail | 2025 |
| Stitchon Ltd | Manufacturing | 2023 |
| Stockfield Garage Ltd | Wholesale & retail | 2009 |
| Stoleru Andrew Transport Ltd | Transport & logistics | 2019 |
| Stone Galaxy Ltd | Wholesale & retail | 2019 |
| Stonecase Limited | Construction | 2019 |
| Stonecase Properties Limited | Real estate | 2024 |
| Stonegate Investment Group Ltd | Real estate | 2023 |
| Stonevale Properties Limited | Real estate | 2025 |
| Stop & Go Car Wash Ltd | Administrative & support | 2021 |
| Storagezoid Limited | Arts & recreation | 2021 |
| Storium Ltd | Wholesale & retail | 2023 |
| Stormaster Fabrics Limited | Extraterritorial | 1988 |
| Storyfiers Ltd | Information & communication | 2023 |
| STR8 Customs Ltd | Wholesale & retail | 2025 |
| Strada Construction Group Ltd | Wholesale & retail | 2019 |
| Straight Blast Gym Rochdale Ltd | Arts & recreation | 2026 |
| Strand Window Cleaning Ltd | Administrative & support | 2025 |
| Strands and Scent Ltd | Wholesale & retail | 2025 |
| Strata Administration Software Ltd | Information & communication | 2005 |
| Strathearn Glasgow Limited | Real estate | 2017 |
| Stratoni Limited | Administrative & support | 2009 |
| Stratoscale Ltd | Information & communication | 2025 |
| Stratton Select Ltd | Wholesale & retail | 2026 |
| Streamline Rochdale Ltd | Transport & logistics | 2025 |
| Streetwise (Milnrow) Ltd | Professional & scientific | 2013 |
| Streetwise (Norden) Ltd | Professional & scientific | 2013 |
| Strengthbodyandmind Ltd | Wholesale & retail | 2025 |
| Strike Conditioning Ltd | Arts & recreation | 2021 |
| Stuart LEE Construction Limited | Construction | 2004 |
| Stuart Smith Ltd | Construction | 2011 |
| Stuart Timpson Ltd | Construction | 2017 |
| Student Showdown Ltd | Arts & recreation | 2024 |
| Student Village Gardens Ltd | Real estate | 2015 |
| Studio Eleven Limited | Professional & scientific | 2025 |
| STUDIO20 Hair & Beauty Ltd | Other services | 2021 |
| Study Shield Limited | Financial services | 2025 |
| Style Your Birth Ltd | Health & social care | 2025 |
| Stylo Group Limited | Wholesale & retail | 2023 |
| Stylo Optical Limited | Health & social care | 2017 |
| Styluxc Ltd | Wholesale & retail | 2024 |
| Suaj Limited | Real estate | 2025 |
| Such a Sweetheart Ltd | Wholesale & retail | 2022 |