| Cloudbass Limited | Information & communication | 2002 |
| Cloudbass Multimedia Limited | Information & communication | 2009 |
| CLW Care Services Ltd | Administrative & support | 2024 |
| CMU Trading Ltd | Wholesale & retail | 2009 |
| Cocoa Lime Limited | Wholesale & retail | 2022 |
| Codnor CUT Ltd | Other services | 2025 |
| Codnor Express Ltd | Hospitality | 2026 |
| Codnor Laser Fabrications Limited | Manufacturing | 2025 |
| Collins Demolition Ltd | Construction | 2016 |
| Collins Earthworks (Transport) Limited | Transport & logistics | 2018 |
| Collins Earthworks Limited | Construction | 2000 |
| Collins Plant Sales Limited | Wholesale & retail | 2019 |
| Colquill Four Limited | Real estate | 1994 |
| Colquill Limited | Real estate | 1961 |
| Colquill Mansions Limited | Real estate | 1992 |
| Community Directions Ltd | Financial services | 2023 |
| Company Engineering Ltd | Professional & scientific | 2021 |
| Connect 2 Promote Ltd | Professional & scientific | 2011 |
| Connect Hardware Ltd | Wholesale & retail | 2025 |
| Control Command Solutions Ltd | Professional & scientific | 2014 |
| Control Pro London Limited | Manufacturing | 2021 |
| COPPER35 Ltd | Information & communication | 2023 |
| Costello Aesthetics Ltd | Health & social care | 2023 |
| Countabean Ltd | Administrative & support | 2018 |
| Coupland Plumbing & Heating Limited | Construction | 2012 |
| Coupland Properties Ltd | Real estate | 2024 |
| COVER3 Projects Ltd | Construction | 2024 |
| Cpcf Ltd | Professional & scientific | 2025 |
| Crane Investment Analysis Limited | Administrative & support | 1987 |
| Cravens Kitchen Ltd | Hospitality | 2025 |
| Creative Media Magazines Limited | Information & communication | 2017 |
| Crenapol Limited | Manufacturing | 2025 |
| Crescent Portfolios Limited | Real estate | 1992 |
| Critical Critters Veterinary Services Limited | Professional & scientific | 2016 |
| Crown Construction (Contracting) Limited | Construction | 1997 |
| Crown Construction (Developments) Limited | Construction | 1999 |
| Crown Home Assist Limited | Construction | 2005 |
| Crystal Clean Cleaning Services Ltd | Administrative & support | 2024 |
| CTC Medical Limited | Health & social care | 2022 |
| CTH (GB) Limited | Financial services | 2009 |
| Culture Hub Limited | Professional & scientific | 2025 |
| Current Collection Solutions Limited | Professional & scientific | 2011 |
| Cutlers Court RTM Company Limited | Households | 2012 |
| Cyber Limited | Information & communication | 2015 |
| D & T Hospitality Ltd | Hospitality | 2019 |
| D a Spray Limited | Construction | 2003 |
| D C Grounds Maintenance Limited | Administrative & support | 2019 |
| D Fletcher Joinery Ltd | Construction | 2017 |
| D&S Contracting Services T/A Amber Fencing & Concrete Products Ltd | Construction | 2020 |
| DAB Skills Limited | Information & communication | 2022 |
| Daju Ltd | Financial services | 2014 |
| Dale Abbey Limited | Construction | 1997 |
| Datum Surveying Services Limited | Administrative & support | 2008 |
| Dave Clarke Electrical Services Limited | Construction | 2002 |
| David Sheldon Associates Ltd | Professional & scientific | 2011 |
| Davis Allan IT Associates Ltd | Administrative & support | 2025 |
| DBR Promotions Limited | Arts & recreation | 2018 |
| DC Pumping Limited | Construction | 2019 |
| DD Quality Drives & Patios Ltd | Construction | 2022 |
| Death and Taxes (Midlands) Limited | Professional & scientific | 2017 |
| DEB Group Holdings Limited | Professional & scientific | 2010 |
| DEB Holdings Limited | Administrative & support | 2000 |
| DEB IP Limited | Administrative & support | 1999 |
| Decx Limited | Administrative & support | 2011 |
| Denby Bathrooms Ltd | Construction | 2021 |
| Denby Equestrian Centre Ltd | Arts & recreation | 2020 |
| Denby Properties Limited | Real estate | 2009 |
| Denby Property Services Ltd | Construction | 2024 |
| Dent to Shine Ltd | Wholesale & retail | 2026 |
| Derby GAS Services Ltd | Construction | 2013 |
| Derby West Property Limited | Real estate | 2019 |
| Derbyshire Accounting Services Ltd | Professional & scientific | 2012 |
| Derbyshire Autism Services Ltd | Other services | 2004 |
| Derbyshire Business Solutions Ltd | Administrative & support | 2018 |
| Derbyshire Carers Association | Administrative & support | 1996 |
| Derbyshire Energy Solutions Limited | Construction | 2013 |
| Derbyshire Floorcraft Limited | Construction | 2004 |
| Derbyshire Gymnastics Academy CIC | Arts & recreation | 2025 |
| Derbyshire Housing Limited | Real estate | 2010 |
| Derbyshire Leasing Limited | Real estate | 2021 |
| Derbyshire Mobility Limited | Manufacturing | 2017 |
| Derbyshire Rubber Roofing Limited | Construction | 2003 |
| Derbyshire Used Van Sales Limited | Wholesale & retail | 2022 |
| Derwent Sash Windows Limited | Construction | 2007 |
| Derwent Sash Windows Trustee Ltd | Professional & scientific | 2024 |
| Designer Carpets & Remnants Ltd | Wholesale & retail | 2011 |
| Detection Technologies Limited | Manufacturing | 2007 |
| Dexter's Doggy Daycare Ltd | Other services | 2025 |
| Dexter's Training Academy Limited | Education | 2026 |
| Dgemm Holdings Limited | Real estate | 2019 |
| DIGITAL4HEALTH UK Ltd | Professional & scientific | 2025 |
| Distillers of Surrey Limited | Manufacturing | 2016 |
| Djfo Ltd | Construction | 2026 |
| DM Global Network Limited | Manufacturing | 2025 |
| DMC Services (Ripley) Ltd | Wholesale & retail | 2026 |
| DNS (Midlands) Limited | Construction | 1998 |
| Dojan Waste Management Services Limited | Water & waste | 2003 |
| Dollys (Belper) Limited | Wholesale & retail | 2025 |
| Doorxpert Limited | Professional & scientific | 2025 |
| Double Glazing Repair Service Limited | Construction | 2021 |