| Runandjump Limited | Professional & scientific | 2005 |
| Rungpur Limited | Wholesale & retail | 2012 |
| Rvdh Consulting Services Limited | Professional & scientific | 2017 |
| Rwtsc Ltd | Professional & scientific | 2026 |
| Ryan Knight Ltd | Professional & scientific | 2025 |
| S & B Industries Limited | Wholesale & retail | 2014 |
| S & I ROY Property Limited | Real estate | 2023 |
| S & IC (UK) Limited | Real estate | 2023 |
| S & S Bistro Ltd | Hospitality | 2016 |
| S Carter Ltd | Professional & scientific | 2026 |
| S&Dg Partners Ltd | Administrative & support | 2020 |
| S. Swain Consulting Ltd | Professional & scientific | 2020 |
| S.A.F. Investments Limited | Real estate | 1991 |
| S.W.Brooks & Co.Limited | Construction | 1960 |
| Saffron Grove Management Company Limited | Households | 2020 |
| Sakuraclub Ltd | Hospitality | 2022 |
| Salf Investments Limited | Real estate | 2014 |
| Sallan Limited | Information & communication | 2012 |
| Sally Morgan Entertainments Limited | Administrative & support | 2011 |
| Salt Box Productions Ltd | Professional & scientific | 2007 |
| Salvers Bridge Limited | Administrative & support | 2016 |
| SAM Investments Limited | Real estate | 1995 |
| SAM Peat Photography Ltd | Professional & scientific | 2018 |
| Sam's Beautiful Nails Ltd | Other services | 2017 |
| Samai Limited | Wholesale & retail | 2019 |
| Samford's Limited | Administrative & support | 1999 |
| Samon Property Ltd | Real estate | 2023 |
| Samuel James Wake Ltd | Health & social care | 2023 |
| SAN Beck Leisure Limited | Financial services | 2021 |
| Sandcross Church | Other services | 2008 |
| Sanddollar Partnership LLP | | 2024 |
| Sandgate Nominees Limited | Professional & scientific | 2007 |
| Sandstone Productions Ltd | Administrative & support | 2024 |
| Sap-Hire XP Ltd | Administrative & support | 2014 |
| Sapnagroup Ltd | Information & communication | 2002 |
| Saprit Group Ltd | Information & communication | 2025 |
| Sarah Coxon Management Limited | Arts & recreation | 2019 |
| Sarah E Smith Consultancy Ltd | Professional & scientific | 2019 |
| Sarah Hilsley Design Limited | Professional & scientific | 2014 |
| Sargasso Networks Limited | Information & communication | 2007 |
| SARL1 Ltd | Construction | 2019 |
| Sato Consulting Limited | Administrative & support | 2010 |
| Saunders Developments Limited | Construction | 2016 |
| Savannah Civils UK Limited | Construction | 2026 |
| Savannah Imports UK Limited | Wholesale & retail | 2023 |
| Sawyer Electrical Installations Limited | Construction | 2016 |
| Saxjo Limited | Professional & scientific | 2018 |
| Saxonbury Services Limited | Real estate | 2003 |
| SB Lighting Limited | Information & communication | 2014 |
| Sbes Limited | Construction | 1997 |
| SC Propconsult Ltd | Professional & scientific | 2023 |
| Scanaudio Limited | Manufacturing | 1994 |
| SCE Management & Consultancy Ltd. | Professional & scientific | 1995 |
| School Lane (West Lulworth) Management Limited | Households | 2021 |
| Schroeder Therapeutics Ltd | Administrative & support | 2017 |
| Scopeman Ltd | Wholesale & retail | 2025 |
| Scott B Holdings Limited | Real estate | 2025 |
| Scovell and Sons Ltd | Administrative & support | 2012 |
| Screwpack (Fasteners) Limited | Wholesale & retail | 1973 |
| Scriven Commercial, Recreational & Industrial Ventures Ltd | Health & social care | 2026 |
| Scslfm Limited | Transport & logistics | 2016 |
| Scta Theatre Academy Limited | Arts & recreation | 2019 |
| SDX Services Ltd. | Construction | 2002 |
| Sea Services International Limited | Transport & logistics | 2005 |
| Seale Hill Management Company Limited | Real estate | 2012 |
| Seamless Developments Ltd | Construction | 2022 |
| Seaswan Investments Limited | Real estate | 2014 |
| Secret Label Interiors Ltd | Professional & scientific | 2019 |
| Secure Dog Fields UK Ltd | Arts & recreation | 2025 |
| Seedlight Advisory Ltd | Professional & scientific | 2026 |
| Segall Limited | Real estate | 2020 |
| Sehas Limited | Administrative & support | 2004 |
| Seine Rigger Limited | Hospitality | 2006 |
| Selcs Ltd | Health & social care | 2010 |
| Select Vehicle Solutions Limited | Wholesale & retail | 2006 |
| Senator Foods Limited | Transport & logistics | 1989 |
| Senator Lubricants Ltd. | Extraterritorial | 1991 |
| Senergy Cooling Limited | Construction | 2024 |
| Senergy Group Limited | Other services | 2020 |
| Senergy Heating Limited | Construction | 2020 |
| Sensory Steps Ltd | Health & social care | 2012 |
| Sente Limited | Information & communication | 1993 |
| Sentinel Internet Communications Limited | Information & communication | 2003 |
| Seoo Ltd | Education | 2023 |
| Sequence (Iver 2) Propco UK Limited | Real estate | 2026 |
| Sequence (Iver 2) UK Limited | Real estate | 2026 |
| Sequence (Iver) Propco UK Limited | Real estate | 2024 |
| Sequence (Iver) UK Limited | Real estate | 2024 |
| Sequoya Business Growth Limited | Professional & scientific | 2009 |
| Serendib Group Ltd | Real estate | 2020 |
| Serenity Consulting Limited | Professional & scientific | 2022 |
| Sesca Limited | Education | 2000 |
| Sesmotorsport Ltd | Transport & logistics | 2024 |
| Sessions Media Ltd | Information & communication | 2021 |
| Sett Planning & Architecture Limited | Professional & scientific | 2021 |
| Seven Stars Leigh Ltd | Hospitality | 2021 |
| Seven X Consulting Limited | Professional & scientific | 2018 |
| Sevenhill Group Ltd | Professional & scientific | 2005 |
| SF Executive Services Ltd | Administrative & support | 2025 |
| SG Flowtech Ltd | Construction | 2025 |