| SR Taylor Education Consultancy Ltd | Education | 2015 |
| SS Fibre Installations Ltd | Administrative & support | 2023 |
| SS Tuning Ltd | Wholesale & retail | 2018 |
| Ssas Bureau Limited | Administrative & support | 2023 |
| SSD Projects Limited | Professional & scientific | 2015 |
| Sspowersystem Ltd | Construction | 2025 |
| ST Antique Jewellery Refiners Limited | Wholesale & retail | 2020 |
| ST Martins Care Home Ltd | Health & social care | 2016 |
| ST Space Trader Ltd | Wholesale & retail | 2025 |
| St@Y Home Limited | Health & social care | 2011 |
| Stability Funding Growth Limited | Financial services | 2012 |
| Stage Build UK Ltd | Arts & recreation | 2026 |
| Stamps by Post Ltd | Other services | 2021 |
| Stamps Landscaping Ltd | Administrative & support | 2025 |
| Stansbie Engineering Limited | Manufacturing | 2002 |
| Star 365 Property Management Ltd | Real estate | 2019 |
| Starlight ERP Consultancy Ltd | Information & communication | 2008 |
| Startpoint Consulting Limited | Professional & scientific | 2009 |
| State LEE Holdings Ltd | Financial services | 2019 |
| Station Approach Boutique Stays Limited | Hospitality | 2024 |
| Stealth Motorcycles Limited | Wholesale & retail | 2006 |
| Steatite Limited | Manufacturing | 2002 |
| Stedwaygb Limited | Education | 2021 |
| Stegaru Alexandru Trans Ltd | Transport & logistics | 2015 |
| Stegaru Group Ltd | Transport & logistics | 2016 |
| Stellier Limited | Wholesale & retail | 2015 |
| Stenergy (Worcester) Limited | Energy | 2020 |
| Stennard Property Limited | Construction | 2012 |
| Step UP Training and Care Ltd | Public administration | 2021 |
| Stephen Alexander Consulting Limited | Administrative & support | 2022 |
| Steps 4 Youth CIC | Other services | 2024 |
| Stepup Stairs Ltd | Wholesale & retail | 2025 |
| Sterling Carz Ltd | Other services | 2009 |
| Sterling Energy Ltd | Construction | 2023 |
| Steve Woodward Limited | Agriculture & fishing | 2001 |
| Stfg Ltd | Financial services | 2021 |
| Sticky Art Customs Ltd | Manufacturing | 2025 |
| Sticky Art UK Ltd | Professional & scientific | 2019 |
| Stitch Holdings Ltd | Financial services | 2025 |
| Stock & Lindsay Limited | Wholesale & retail | 1986 |
| Stoke Heath Homecare Ltd. | Health & social care | 2016 |
| Stokes PS Ltd | Real estate | 2017 |
| Stone & Oak Ltd | Construction | 2026 |
| Stoney Court (Tardebigge) Management Company Limited | Households | 2025 |
| Stony Flynn Limited | Households | 2014 |
| Stop N' Steer Limited | Professional & scientific | 2002 |
| Storey Carpets Limited | Extraterritorial | 1973 |
| Stormwell Limited | Construction | 2018 |
| Storwell Systems Limited | Professional & scientific | 1982 |
| Straight Consulting Limited | Professional & scientific | 2008 |
| Straight Forward Supplies Ltd | Wholesale & retail | 2025 |
| Straightmile Construction Limited | Construction | 2020 |
| Stratagema Limited | Professional & scientific | 2024 |
| Strategic Insiders Limited | Other services | 2016 |
| Strategic Reserve Asset Management Limited | Administrative & support | 2024 |
| Stratford Aircon Ltd | Construction | 2023 |
| Stratton Technical Services Limited | Professional & scientific | 2020 |
| Street Food Truck UK Ltd | Hospitality | 2024 |
| STRENGTH2PERFORM Limited | Extraterritorial | 2011 |
| Stress Less Tax Limited | Professional & scientific | 2014 |
| Stride Industrial Group Ltd | Administrative & support | 2014 |
| Strikt Limited | Professional & scientific | 2013 |
| Strutt IT Ltd | Other services | 2025 |
| Stuart DA Shaw Consultancy Ltd | Professional & scientific | 2026 |
| Stuart Safety Consultants Ltd | Professional & scientific | 2021 |
| Studio Flare Ltd | Arts & recreation | 2023 |
| Studio Tomato Ltd | Arts & recreation | 2026 |
| Studiome Ltd | Information & communication | 2014 |
| Studley Road Ltd | Real estate | 2026 |
| Studley Special Steels Limited | Wholesale & retail | 2014 |
| Studley Trees & Hedges Limited | Administrative & support | 2022 |
| STW Property Maintenance Ltd | Administrative & support | 2015 |
| Suaro Limited | Wholesale & retail | 2015 |
| Sublime Music Ltd | Arts & recreation | 2021 |
| Sublime Slime Ltd | Other services | 2026 |
| Subscan Surveys Ltd | Professional & scientific | 2025 |
| SUE Watson Books Limited | Information & communication | 2020 |
| Sufi Logistics Ltd | Transport & logistics | 2025 |
| Sulaymani Shawarma Hall Green Ltd | Hospitality | 2026 |
| Suleman Property Group Ltd | Real estate | 2025 |
| Summersons Clocks Limited | Wholesale & retail | 2002 |
| Summit Compliance Services Limited | Professional & scientific | 2022 |
| Summit Training and Consultancy Limited | Professional & scientific | 2021 |
| Sumtasa Ltd | Wholesale & retail | 2019 |
| Sun & Health International Limited | Manufacturing | 1995 |
| Sun City Tanning Studio Limited | Extraterritorial | 2002 |
| Sunnysapps Ltd | Information & communication | 2023 |
| Sunrise Upvc Ltd | Construction | 2023 |
| Sunstone Optics Ltd | Information & communication | 2018 |
| Supaprint (Redditch) Limited | Manufacturing | 1981 |
| Supaprint Limited | Manufacturing | 2003 |
| Super Freak Ltd | Arts & recreation | 2021 |
| Superclean Property Services (UK) Ltd | Administrative & support | 2019 |
| Supply Chain Solved Limited | Administrative & support | 2012 |
| Suragen Ltd | Health & social care | 2023 |
| Surch 360 Limited | Information & communication | 2024 |
| Surface Demolition Limited | Construction | 2024 |
| Surface Treatment Ltd | Manufacturing | 2005 |
| Sussex House (Glenilla Road) Limited | Households | 2001 |
| Sustainable Air Solutions Limited | Manufacturing | 2023 |