| Skyrocket Vehicle Rentals Limited | Transport & logistics | 2017 |
| SLH Signage and Graphics Installation Ltd | Construction | 2025 |
| Slimline Sliding Doors Ltd | Construction | 2022 |
| SLK Roofing & Building Services Limited | Construction | 2023 |
| Smart Drive Driver Training Limited | Education | 2015 |
| Smart Health Suite Limited | Information & communication | 2024 |
| Smarts Hill Studios Limited | Arts & recreation | 2006 |
| Smartshow UK Ltd | Other services | 2019 |
| Smartsim Limited | Information & communication | 2017 |
| Smartwatt Energy Consultants Ltd | Professional & scientific | 2025 |
| SMASH690 Limited | Information & communication | 2023 |
| SMC Construction Kent Ltd | Construction | 2018 |
| Smith Assets Limited | Real estate | 2026 |
| Smith Building Services Kent Ltd | Construction | 2020 |
| SML Properties (Kent) Limited | Real estate | 2023 |
| Smoke & Co Restaurant Ltd | Hospitality | 2025 |
| Smoked Ramsgate Ltd | Hospitality | 2022 |
| Smpn Investments Limited | Professional & scientific | 2022 |
| Smugglers Management Company Limited | Households | 2016 |
| SMW Consulting Limited | Professional & scientific | 2018 |
| Snip Snap Consulting Limited | Professional & scientific | 2016 |
| Social Records Ltd | Arts & recreation | 2022 |
| Social Spritz Bar Ltd | Hospitality | 2026 |
| Socket & Plug Limited | Agriculture & fishing | 2014 |
| Softwayre Limited | Manufacturing | 2010 |
| Solaris Automotive Limited | Wholesale & retail | 2013 |
| Solarium Point Beauty & Hair Ltd | Other services | 2022 |
| Solarium Point Hair Ltd | Other services | 2015 |
| Solarium Point Ltd | Households | 2015 |
| Soleil Homes Ltd | Real estate | 2020 |
| Solstice Bars (South East) Ltd | Hospitality | 2025 |
| Solution 4YOU Group Limited | Transport & logistics | 2021 |
| Somersby Estates Limited | Real estate | 2011 |
| Something Different Entertainment Ltd | Arts & recreation | 2012 |
| Sonder Arts CIC | Education | 2024 |
| Sonny and Arnie Ltd | Construction | 2007 |
| Sonrica Ltd | Health & social care | 2019 |
| Sophie - Medical Skin Clinic Ltd | Other services | 2026 |
| Sorcha Light Ltd | Professional & scientific | 2023 |
| Sorrel Ventures Ltd | Professional & scientific | 2026 |
| Sottosopra Ltd | Arts & recreation | 2019 |
| Soulshack Productions Limited | Arts & recreation | 2009 |
| Sounds Like Art CIC | Information & communication | 2022 |
| South East Accounting Tax & Business Services Ltd | Professional & scientific | 2018 |
| South East Architectural Services Limited | Professional & scientific | 2005 |
| South East Carpentry & Construction Ltd | Construction | 2024 |
| South East Collections Limited | Administrative & support | 2024 |
| South East Commercial Cleaners Ltd | Administrative & support | 2024 |
| South East Food Trucks Ltd | Hospitality | 2026 |
| South East Kent Insurance Services Limited | Administrative & support | 1996 |
| South East Ultrasound Limited | Administrative & support | 2012 |
| Southeast Collection Services Ltd | Administrative & support | 2018 |
| Southeastern Diesel Services (UK) Ltd | Professional & scientific | 2012 |
| Sovereign Hill Ltd | Professional & scientific | 2019 |
| SP Capital Trading Limited | Wholesale & retail | 2022 |
| Spain's Mots Ltd | Wholesale & retail | 2021 |
| Spark Film Production Ltd | Administrative & support | 2013 |
| Sparkling Memories by CS Ltd | Professional & scientific | 2025 |
| Sparrow Care Consultancy Ltd | Professional & scientific | 2025 |
| Spartan Outdoor Installations Ltd | Manufacturing | 2024 |
| Speed Majestic Ltd | Education | 2023 |
| Spellbound in Sandwich Limited | Wholesale & retail | 2025 |
| Spellpage Limited | Other services | 2009 |
| Spencer Court Hotel Limited | Hospitality | 2012 |
| Spiral Lifts Limited | Construction | 2013 |
| Spiral Music Limited | Information & communication | 1999 |
| Spitfire Fitness Ltd | Arts & recreation | 2015 |
| Spitfire Preservations Limited | Education | 2011 |
| Sportsman MS Ltd | Construction | 2021 |
| Spray Styles Coatings Ltd | Construction | 2019 |
| Spring Clean Homes Ltd | Other services | 2012 |
| Spritz Cocktails Limited | Hospitality | 2025 |
| Spurling Cannon Audit Limited | Professional & scientific | 2020 |
| Spurling Cannon Community Fund | Administrative & support | 2012 |
| Spurling Cannon Limited | Professional & scientific | 2003 |
| Square Triangle Circle Ltd | Administrative & support | 2017 |
| Squiggle Media Limited | Manufacturing | 2004 |
| SRB Mechanical Services Ltd | Wholesale & retail | 2022 |
| SRK Projects Ltd | Manufacturing | 2021 |
| SS Car Sales Thanet Limited | Wholesale & retail | 2024 |
| Ss&E Investments Ltd | Financial services | 2022 |
| ST Georges Ramsgate Community Development Trust C.I.C. | Professional & scientific | 2015 |
| ST James's Foreign Policy Group Limited | Professional & scientific | 2024 |
| ST Lawrence (UK) LLP | | 2007 |
| ST Lukes Enterprise Ltd | Wholesale & retail | 2024 |
| ST Mildreds Mews Limited | Real estate | 2009 |
| ST Peter Street (Maidstone) Flat Management Company Limited | Households | 2003 |
| ST. Augustines Golf Club (Ramsgate) Limited | Arts & recreation | 1922 |
| ST. Lawrence (Ramsgate) Management Limited | Households | 2007 |
| ST. Lawrence College Enterprises Ltd. | Education | 1995 |
| ST. Stephens Park Management Ltd | Households | 2022 |
| Stagg Homes Limited | Real estate | 2021 |
| Stagg Properties (Kent) Limited | Real estate | 2021 |
| Stains Away Ltd | Administrative & support | 2018 |
| Stak.Life CIC | Education | 2024 |
| Standard Heritage Ltd | Professional & scientific | 2014 |
| Star Fish and Chips Ltd | Hospitality | 2025 |
| Star of China Chinese Takeaway Limited | Hospitality | 2025 |
| Starburn Learning Limited | Education | 2021 |
| Starfleet Engineering Ltd | Extraterritorial | 2019 |