| Samuel SAM Limited | Health & social care | 2020 |
| Samyx Ltd | Real estate | 2015 |
| Sands Restaurant Limited | Wholesale & retail | 2007 |
| Saracens Holdings II Ltd | Real estate | 2020 |
| Saracens Holdings III Ltd | Real estate | 2025 |
| Saracens Holdings Ltd | Real estate | 2019 |
| Sarah Exporters Limited | Wholesale & retail | 2018 |
| Sargood Holdings Limited | Real estate | 2023 |
| Sarnia Motorsport Limited | Arts & recreation | 2022 |
| Sash Window Websites Ltd | Information & communication | 2025 |
| Saunders Park Homes Limited | Hospitality | 1978 |
| Savage & Pottinger Design Ltd | Professional & scientific | 2013 |
| Sawkins Double Glazing Limited | Construction | 2016 |
| Saxon Reach (Cliffsend) Management Ltd | Households | 2021 |
| SC Heating GAS and Plumbing Services Ltd | Construction | 2021 |
| Schooners Consultancy Limited | Professional & scientific | 2025 |
| Scimitar Consultancy Ltd | Professional & scientific | 2019 |
| Sclb Ltd | Construction | 2022 |
| Scoop Ramsgate Ltd | Wholesale & retail | 2026 |
| Scotney Gardens RTM Company Ltd | Households | 2014 |
| Scott Alexander Solutions Limited | Professional & scientific | 2015 |
| Scott Downton Surveying Services Ltd | Professional & scientific | 2018 |
| Scove Limited | Hospitality | 2018 |
| Screaming Alley CIC | Arts & recreation | 2019 |
| Sdwm Consultancy Ltd | Administrative & support | 2021 |
| SE Neml Ltd | Hospitality | 2023 |
| Sea and Forest Property Ltd | Real estate | 2025 |
| Sea Flats Limited | Hospitality | 1990 |
| Sea View Deal Limited | Hospitality | 2020 |
| Seabird Ramsgate Ltd | Hospitality | 2025 |
| Seafield Mews Road Management Limited | Households | 2016 |
| Seaside Media and Accommodation Hub Ltd | Information & communication | 2023 |
| Seaview Cleaning Ltd | Administrative & support | 2025 |
| Seaward Color Copy Limited | Manufacturing | 1997 |
| Second Nest Ltd | Hospitality | 2016 |
| Security Innovation Services Ltd | Administrative & support | 2025 |
| Seer Insight Ltd | Information & communication | 2014 |
| Sellmyownhome.Uk Limited | Professional & scientific | 2018 |
| Semt Ltd | Education | 2024 |
| Sendhelp Consultancy Ltd | Education | 2025 |
| Sensitive Data Systems Limited | Information & communication | 1988 |
| Sentra Capital Investments Limited | Financial services | 2015 |
| Sequoia Wealth Ltd | Real estate | 2020 |
| Sequoia Wealth SPV 1 Ltd | Real estate | 2020 |
| Serendib Naturals Limited | Agriculture & fishing | 2020 |
| Serendipia Limited | Wholesale & retail | 2024 |
| Servan Limited | Hospitality | 2019 |
| Seven Kings Studio Ltd | Manufacturing | 2018 |
| Sevtech Limited | Professional & scientific | 2014 |
| SEW Printed Ltd | Wholesale & retail | 2024 |
| SF Ultrasound Limited | Health & social care | 2021 |
| SFJ Electrical Installations Limited | Construction | 2015 |
| SFM Sales Ltd | Professional & scientific | 2023 |
| Sfpc Ltd | Professional & scientific | 2020 |
| SG Mechanical Consultants Ltd | Professional & scientific | 2025 |
| SGS South-East Ltd | Construction | 2019 |
| Shah Corporate Group Ltd | Real estate | 2025 |
| Shahjee Limited | Wholesale & retail | 2011 |
| Shao/Todd Ltd | Construction | 2019 |
| Sharpe TCG Ltd | Wholesale & retail | 2026 |
| Sheardown Consultancy Services Ltd | Professional & scientific | 2017 |
| Shellygarrattphotography Ltd | Professional & scientific | 2025 |
| Shillings Ltd. | Manufacturing | 1997 |
| Shine on YOU Ltd | Manufacturing | 2021 |
| Shivering Sands Brewery Ltd | Manufacturing | 2019 |
| Shopedia Limited | Wholesale & retail | 2025 |
| Shore Close (Birchington) Flat Management Limited | Households | 1987 |
| Side and Hill Ltd | Hospitality | 2023 |
| Sideways Press Ltd | Information & communication | 2025 |
| Sifa Design Ltd | Professional & scientific | 2026 |
| Sigona Girls Limited | Hospitality | 2024 |
| Silent Running Productions Ltd | Administrative & support | 2016 |
| Silicon Coast Ltd | Information & communication | 2023 |
| Sillett Associates Limited | Other services | 2024 |
| Silver Arrows Automobiles Limited | Wholesale & retail | 1989 |
| Silver Arrows Properties Ltd | Extraterritorial | 2006 |
| Silver Slipper Performing Art School Ltd | Arts & recreation | 2018 |
| Silver Tots Limited | Health & social care | 2026 |
| Silverback Online Limited | Wholesale & retail | 2022 |
| Silvers Brunches Ltd | Hospitality | 2025 |
| Silvers Margate Ltd | Hospitality | 2021 |
| Silvers PUB Company Ltd | Hospitality | 2026 |
| Simon Heard Electrical Ltd | Construction | 2016 |
| Simon K Matthews Creative Ltd | Information & communication | 2017 |
| Simon Leigh Harris Ltd | Professional & scientific | 2026 |
| Simply Business Club Ltd | Information & communication | 2023 |
| Sims Polishing Ltd | Other services | 2016 |
| Sion House Management Company Limited | Households | 2007 |
| Siskin Consulting Limited | Education | 2024 |
| Site Salvage Ltd | Administrative & support | 2010 |
| Sitg-Consulting Ltd | Information & communication | 2025 |
| Sixteen Melrose Avenue Management Limited | Households | 1989 |
| SJB Rail Consultants Limited | Professional & scientific | 2014 |
| Skar Construction Management Ltd | Construction | 2013 |
| Skill Beacon Ltd | Education | 2022 |
| Skmc Property Limited | Real estate | 2020 |
| Skstats Limited | Professional & scientific | 2020 |
| Skyeskyns Limited | Wholesale & retail | 2004 |
| Skyline Mobile Car Valeting Ltd | Administrative & support | 2025 |
| Skynet Holdings Limited | Professional & scientific | 2016 |