| Spectraders Ltd. | Real estate | 1994 |
| Speed Signs & Designs Limited | Manufacturing | 2020 |
| Speedo Angels Limited | Wholesale & retail | 2016 |
| Speller’S Sparks Ltd | Construction | 2022 |
| Spinfoam Films Limited | Information & communication | 2022 |
| Spirit Operations Ltd | Manufacturing | 2012 |
| Splash Inns Ltd. | Hospitality | 2004 |
| Sport Xperimental Limited | Manufacturing | 2003 |
| Sporting Family Change Foundation | Arts & recreation | 2015 |
| Sporting Sensations Ltd | Arts & recreation | 2024 |
| Sportstrix Direct Limited | | 2011 |
| Spot JOS Limited | Wholesale & retail | 2020 |
| Spotted Dog Productions Limited | Information & communication | 2022 |
| Spower Finco 1 (UK) Ltd. | Financial services | 2015 |
| Spower Holdco 1 (UK) Ltd. | Financial services | 2015 |
| Spray TEK (UK) Ltd | Wholesale & retail | 2012 |
| Springer Build Ltd | Construction | 2023 |
| Springfield Plant Services Limited | Administrative & support | 2007 |
| Springfield Road Surfacing Co. Limited | Construction | 2003 |
| Sprout Accountancy Ltd | Professional & scientific | 2018 |
| Sprout Consulting Ltd | Professional & scientific | 2018 |
| SR Catchers Ltd | Hospitality | 2013 |
| SR Property Bath Limited | Real estate | 2022 |
| SSD Print Management & Broking Ltd | Manufacturing | 2020 |
| ST Anne's Capital Limited | Financial services | 2013 |
| ST Automotive Consultancy Ltd | Wholesale & retail | 2018 |
| ST Cuthberts Maintenance Ltd | Construction | 2024 |
| ST Georges House Tiverton LLP | | 2024 |
| ST Hugh's Property Management Limited | Households | 2022 |
| Stable Print & Design Limited | Manufacturing | 2015 |
| Stanisha Properties Limited | Real estate | 2025 |
| Starfish Divers Ltd | Health & social care | 2021 |
| Staroncology Limited | Health & social care | 2021 |
| Stealth Brew Co Limited | Manufacturing | 2012 |
| Sterimed UK Holdings Ltd | Professional & scientific | 2015 |
| Steve Bellamy Carpets Ltd | Wholesale & retail | 2013 |
| Steve James Electrical Limited | Professional & scientific | 2011 |
| Steve Margary Carpets and Flooring Ltd | Other services | 2010 |
| Stevens & Barnes Building Contractors Ltd | Construction | 2014 |
| Stoneable Heights Radstock Management Company Limited | Households | 2010 |
| Stoneman Contractors Ltd | Construction | 2026 |
| Stonescafebar Ltd | Hospitality | 2019 |
| Stratos Studios Limited | Manufacturing | 2025 |
| Straysparks Creative Metalwork Limited | Manufacturing | 2012 |
| Straysparks Limited | Manufacturing | 2017 |
| Strike IT Rich Limited | Arts & recreation | 2002 |
| Stringers Plumbing and Heating Limited | Construction | 2022 |
| Stuart Adam Engineering Ltd | Professional & scientific | 2021 |
| Stuart Bailey Roofing Limited | Construction | 2022 |
| Stuart Barnes Consulting Limited | Arts & recreation | 2022 |
| Studio 74 Creative Design Ltd | Professional & scientific | 2011 |
| Studio Four Point TEN Ltd | Professional & scientific | 2023 |
| Studio Spacebrand Limited | Professional & scientific | 2017 |
| Stylistic Steel Designs Ltd | Manufacturing | 2023 |
| Stylistic Steel Ltd | Manufacturing | 2013 |
| Sucasa Holdings Co. Limited | Financial services | 2026 |
| SUE Hill Dance Limited | Arts & recreation | 2007 |
| Sunflower Film & Creative Agency Limited | Professional & scientific | 2015 |
| Sunflowers Nursery Limited | Education | 2003 |
| Sunny Cottages Ltd | Real estate | 2020 |
| Supersabre Limited | Information & communication | 2011 |
| Supplystrides Limited | Professional & scientific | 2023 |
| Surefit-It Limited | Wholesale & retail | 2007 |
| Suretechnet Limited | Extraterritorial | 2020 |
| Surveybase Limited | Professional & scientific | 1998 |
| Sussiekuj Ltd | Transport & logistics | 2024 |
| Sustainicity Ltd | Professional & scientific | 2021 |
| SV Electrical Bath Ltd | Construction | 2025 |
| Swan Advice Network | Information & communication | 2009 |
| Swarbrick Building Limited | Construction | 2011 |
| Swiftcare Pharma Ltd | Wholesale & retail | 2025 |
| Swnfitness Ltd | Arts & recreation | 2020 |
| Sycamore South West Limited | Construction | 2013 |
| Symonds Homes Ltd | Real estate | 2024 |
| Syrinx Skin Care Ltd. | Manufacturing | 2020 |
| T & M Properties (Somerset) Limited | Real estate | 2017 |
| T C & H Marks Limited | Agriculture & fishing | 2016 |
| T Keen Plumbing Solutions Limited | Construction | 2018 |
| T.Darling Plumbing & Heating Ltd | Construction | 2025 |
| TA Electrix Ltd | Construction | 2026 |
| TA the Glow Room Ltd | Other services | 2023 |
| Tailor Pepys Ltd | Manufacturing | 2023 |
| Taiyang Events Ltd | Arts & recreation | 2025 |
| Tamara Rawlingson Plant Limited | Information & communication | 2007 |
| Taptastic Ltd | Manufacturing | 2024 |
| Tavern Motor Club Limited | Other services | 1974 |
| Tax Services Ltd | Extraterritorial | 1997 |
| Taylormade Metal Limited | Professional & scientific | 2019 |
| TCM Partnership Limited | Health & social care | 2008 |
| TDT Preservation Limited | Construction | 2018 |
| TE Creatives Ltd | Information & communication | 2023 |
| Techne Construction Ltd | Construction | 2025 |
| Technical Service Group Limited | Extraterritorial | 2008 |
| Techniglaze Limited | Construction | 1984 |
| Telco Electronics Limited | Information & communication | 2018 |
| TEM Motors Ltd | Wholesale & retail | 2025 |
| Temple Holdings & Investments Ltd | Real estate | 2025 |
| Temple Tuning Limited | Wholesale & retail | 2009 |
| Temuka Limited | Agriculture & fishing | 1978 |
| Terrafluvial Limited | Agriculture & fishing | 2021 |