| EPT Properties Limited | Financial services | 2020 |
| Eqiq Tax Limited | Professional & scientific | 2017 |
| Equine Planning Solutions Limited | Professional & scientific | 2013 |
| Equioils Limited | Manufacturing | 2021 |
| Equip Supplies Limited | Wholesale & retail | 2017 |
| Equipmart Limited | Wholesale & retail | 2009 |
| Equitas Solicitors Limited | Professional & scientific | 2006 |
| Equitation Academy Ltd | Arts & recreation | 2024 |
| Equity Release Assured Limited | Financial services | 2008 |
| Equity Release Club Holdings Limited | Financial services | 2018 |
| ER3D Ltd | Professional & scientific | 2026 |
| ERA Pizzas Ltd | Hospitality | 2026 |
| Ercor Holdings Ltd | Financial services | 2020 |
| Ercor Limited | Real estate | 2005 |
| Erebus Industries Ltd | Manufacturing | 2024 |
| Ergo Wholesale Ltd | Wholesale & retail | 2025 |
| Ergonomic Seating Solutions Limited | Wholesale & retail | 2014 |
| ERI Assured Limited | Administrative & support | 2017 |
| Eric Astbury Holdings Limited | Wholesale & retail | 2023 |
| Eric Card Limited | Information & communication | 2022 |
| Eric Cliffe Limited | Wholesale & retail | 1972 |
| Eric Wright Developments Limited | Real estate | 2009 |
| Eric Wright FM Limited | Real estate | 2002 |
| Eric Wright Homes Limited | Construction | 2001 |
| Eric Wright Water Limited | Construction | 1984 |
| Erik Nicolin Ltd | Transport & logistics | 2025 |
| Erikmfba Ltd | Wholesale & retail | 2025 |
| Erily Limited | Financial services | 2021 |
| Erismann Wallcoverings Limited | Wholesale & retail | 2008 |
| Erithacus Properties Ltd | Real estate | 2015 |
| Erlescote Limited | Real estate | 2003 |
| ERP People Limited | Information & communication | 1995 |
| Erst Ltd | Hospitality | 2018 |
| ES Logistics Ltd | Transport & logistics | 2024 |
| ESB 2019 Limited | Transport & logistics | 2019 |
| Escape (Derby) Ltd | Arts & recreation | 2016 |
| Escape (LIV) Ltd | Arts & recreation | 2016 |
| Escape (Shef) Ltd | Arts & recreation | 2017 |
| Escaperoom (Barrow) Ltd | Other services | 2016 |
| Escaperoom (Leeds) Ltd | Arts & recreation | 2016 |
| Escaperoom (Stoke) Ltd | Other services | 2015 |
| Esendi Services Limited | Administrative & support | 2015 |
| ESG Garages Ltd | Wholesale & retail | 2020 |
| ESG Local Projects Limited | Energy | 2022 |
| ESG Properties Ltd | Real estate | 2020 |
| ESG Scope Zero Limited | Professional & scientific | 2022 |
| ESL Media Limited | Professional & scientific | 2023 |
| Esmail Enterprises Ltd | Wholesale & retail | 2009 |
| ESP Bathrooms Limited | Wholesale & retail | 1991 |
| Espen Clothing Trading Limited | Extraterritorial | 2021 |
| Espl Ltd | Wholesale & retail | 2023 |
| Espo Ltd | Wholesale & retail | 2007 |
| Espoke Living Ltd | Other services | 2016 |
| Espouse Limited | Professional & scientific | 2022 |
| Esprit Hermine Ltd | Wholesale & retail | 2018 |
| Esprom Limited | Construction | 2002 |
| Esquire 1976 UK Ltd | Wholesale & retail | 2026 |
| Essa Courier's Ltd | Transport & logistics | 2022 |
| Essentials Lingerie Limited | Other services | 2003 |
| Essentials One Stop Shop Ltd | Wholesale & retail | 2025 |
| Essex Ground Management Limited | Administrative & support | 2013 |
| Essex of UK Services Ltd | Professional & scientific | 2017 |
| Essex Tree Care Ltd | Administrative & support | 2015 |
| Essuf Limited | Administrative & support | 2018 |
| Estate Agent Socials Ltd | Professional & scientific | 2025 |
| Estate Motors Limited | Transport & logistics | 1988 |
| Estates and Law Limited | Professional & scientific | 2008 |
| Estates and Properties Ltd | Construction | 2023 |
| Estatevision Trading Ltd | Wholesale & retail | 2026 |
| Estee Enterprise Limited | Health & social care | 2023 |
| Ester Bellissimo SEX Therapy Ltd | Health & social care | 2025 |
| Esther Times Ltd | Wholesale & retail | 2021 |
| Esther Unitt Limited | Health & social care | 2019 |
| Esthetik Ltd | Health & social care | 2010 |
| Estospaces Solutions Limited | Real estate | 2025 |
| Estuary Cleaning Ltd | Administrative & support | 2022 |
| Esuite Limited | Information & communication | 2003 |
| Esytrend Ltd | Wholesale & retail | 2026 |
| ETC Urban (Guildhall) Limited | Construction | 2016 |
| Eternal Engravings Ltd | Wholesale & retail | 2023 |
| Eternity Home Care Limited | Health & social care | 2019 |
| Ethiant Brands Ltd | Wholesale & retail | 2023 |
| Ethical Asset Management Limited | Construction | 2010 |
| Ethical Edge Ltd | Administrative & support | 2024 |
| Ethical Pixels Limited | Information & communication | 2019 |
| Ethnic Dimension Limited | Professional & scientific | 2000 |
| Ethos Digital Signage Ltd | Information & communication | 2025 |
| Ethrin Ltd | Information & communication | 2015 |
| Etna Food & Wine Ltd | Wholesale & retail | 2016 |
| Etoile Boutique Hospitality Ltd | Hospitality | 2018 |
| Eton Park Management Company Limited | Other services | 1989 |
| ETR Property Development Ltd | Real estate | 2025 |
| Etrnty Limited | Information & communication | 2025 |
| Ettan IT Consulting Limited | Information & communication | 2026 |
| Eunicar Garage Ltd | Wholesale & retail | 2020 |
| Eunicar Plus Ltd | Wholesale & retail | 2023 |
| Euphoria Dance & Therapy Ltd | Arts & recreation | 2019 |
| Euro Distributors Ltd | Other services | 2013 |
| Euro Mini Market Preston Ltd | Wholesale & retail | 2026 |
| Euro News Ltd | Wholesale & retail | 2017 |