| Salve Investments (Hawarden) Ltd | Real estate | 2017 |
| Salve Investments (Holgate) Ltd | Real estate | 2017 |
| Salve Investments (Maes Mona) Ltd | Real estate | 2017 |
| Salve Investments (Manshaw) Ltd | Real estate | 2017 |
| Salve Investments (Saffron) Ltd | Real estate | 2017 |
| Salve Investments (Sand) Ltd | Real estate | 2017 |
| Salve Investments (Shieldhall) Ltd | Real estate | 2010 |
| Salve Investments (Shirley) Ltd | Real estate | 2019 |
| Salve Investments (Westwood) Ltd | Real estate | 2017 |
| Salve Investments Ltd | Real estate | 2012 |
| Salve Investments Project 13 Ltd | Real estate | 2019 |
| Salve Investments Project 16 Ltd | Real estate | 2019 |
| Salve Investments Project 18 Ltd | Real estate | 2020 |
| Salve Investments Project 19 Ltd | Real estate | 2020 |
| SAM Car Sales Ltd | Wholesale & retail | 2023 |
| SAM Decor Ltd | Construction | 2022 |
| SAM Groundworks Limited | Construction | 2015 |
| SAM Sedgman Ltd | Other services | 2022 |
| SAM Upton Ltd | Construction | 2023 |
| Sama International Ltd | Manufacturing | 2019 |
| Samdot Group Ltd | Construction | 2022 |
| Samlangley Hair Limited | Other services | 2014 |
| SAMONE4SURE Limited | Health & social care | 2024 |
| Sampson Holdings Limited | Real estate | 2018 |
| Sampson Hughes Limited | Administrative & support | 2013 |
| Samra & Daughters Limited | Real estate | 2013 |
| Sams Car Wash Ltd | Professional & scientific | 2013 |
| Sams Place (Samaritans of Portsmouth & East Hampshire) Limited | Wholesale & retail | 2019 |
| Samson Regis Ltd | Information & communication | 2023 |
| SAN Collections Ltd | Wholesale & retail | 2025 |
| Sancorr Limited | Transport & logistics | 2018 |
| Sanctum Freeholds Limited | Real estate | 2024 |
| Sanctum Homes Ltd | Construction | 2018 |
| Sanctum Properties Ltd | Real estate | 2017 |
| Sand & Stone Properties Ltd | Real estate | 2026 |
| Sandford Estates Limited | Administrative & support | 1997 |
| Sandshine Ltd | Professional & scientific | 2018 |
| Sandy Beach Freeholds Limited | Households | 1967 |
| Sandy Point Chandlery Limited | Wholesale & retail | 2018 |
| Sandy's Beach Bar Limited | Hospitality | 2025 |
| Sanga Care Ltd | Administrative & support | 2024 |
| Sankofa Hephaestus Engineering Ltd | Professional & scientific | 2025 |
| Sanskruti & Harsh Ltd | Wholesale & retail | 2026 |
| Sanson Commercial Flooring Ltd | Construction | 2020 |
| Santo the Wellness Collective Limited | Wholesale & retail | 2026 |
| Santos Estates Limited | Real estate | 2025 |
| Sapphire Carpentry and Building Ltd | Construction | 2023 |
| Sapphire Home Solutions Ltd | Households | 2025 |
| Saqs Services Ltd | Professional & scientific | 2019 |
| Sara Restaurant Ltd | Hospitality | 2026 |
| Sara Smith Consulting Ltd | Professional & scientific | 2025 |
| Sarah Florence Limited | Professional & scientific | 2014 |
| Sarah Hartfree Ltd | Health & social care | 2019 |
| Sarah Jill Barke Ltd | Professional & scientific | 2024 |
| Sarah Property Investment Ltd | Real estate | 2025 |
| Sarahstewartsmith Ltd | Administrative & support | 2016 |
| Sarasota Administrators Ltd | Public administration | 2025 |
| Saravanan Elangovan Ltd | Administrative & support | 2019 |
| Sarcon Ltd | Construction | 2026 |
| Sareos Limited | Health & social care | 2023 |
| Sarnia Limited | Professional & scientific | 1980 |
| Sarum Electrical & Mechanical Ltd | Construction | 2017 |
| Sarum Property Investments Ltd | Real estate | 2018 |
| SAS Aesthetics Ltd | Other services | 2019 |
| Sasa Retails Ltd | Wholesale & retail | 2024 |
| Satin Systems Limited | Other services | 1999 |
| Satnaam Limited | Wholesale & retail | 2025 |
| Saturn GAS Heating and Plumbing Ltd | Construction | 2015 |
| Saunders Trading Ltd | Wholesale & retail | 2022 |
| Savage Civil Engineering Ltd | Construction | 2026 |
| Savage Collectibles Limited | Arts & recreation | 2024 |
| Savoury Express Limited | Hospitality | 2015 |
| Saxon Brickwork Ltd | Construction | 2025 |
| Sayasri Retail Limited | Wholesale & retail | 2025 |
| SB King Hair Ltd | Other services | 2020 |
| SB Mart Ltd | Wholesale & retail | 2025 |
| SBC Fitout Ltd | Construction | 2019 |
| SBL Travel Limited | Transport & logistics | 2025 |
| SC Deliveries Limited | Transport & logistics | 2025 |
| SC House Moves Limited | Transport & logistics | 2025 |
| SC Property Group Ltd | Real estate | 2026 |
| SC Spice Ltd | Hospitality | 2026 |
| SC Waste Management Limited | Water & waste | 2025 |
| Scaddan Refrigeration & Air Conditioning Ltd | Energy | 2019 |
| Scaleup Systems Ltd | Professional & scientific | 2023 |
| Scarbro and Knight Ltd | Wholesale & retail | 2015 |
| SCB Distributions Limited | Wholesale & retail | 2025 |
| Schc Ltd | Health & social care | 2010 |
| School of Parenting Ltd | Health & social care | 2016 |
| Scideas Limited | Real estate | 2017 |
| Scion Construction & Development Ltd | Construction | 2010 |
| Scion Construction Management Ltd | Construction | 2018 |
| SCL (Members) Trustee Limited | Professional & scientific | 1997 |
| Scoops Dessert Parlour Ltd | Hospitality | 2022 |
| Scoops Desserts Fareham Limited | Extraterritorial | 2024 |
| Scoops Foodservice Limited | Extraterritorial | 2014 |
| Scoops Gelato Fareham Limited | Extraterritorial | 2024 |
| Scoops Portsmouth Limited | Extraterritorial | 2024 |
| Scoops Southampton Limited | Extraterritorial | 2024 |
| Scoops Southsea Limited | Extraterritorial | 2024 |