| Live Entertainment Technologies Ltd | Information & communication | 2019 |
| Live Escape Rooms Limited | Administrative & support | 2014 |
| Live Quadrics Limited | Information & communication | 2020 |
| Live Sound Music Promotions Ltd | Administrative & support | 2016 |
| Live the Life Unique Ltd | Health & social care | 2025 |
| Livermead House Hotel Limited | Hospitality | 2018 |
| Livewell Primary Care Group Limited | Health & social care | 2022 |
| Livewell Southwest Care Limited | Health & social care | 2017 |
| Livewell Southwest CIC | Health & social care | 2011 |
| Livgreen Ltd | Construction | 2024 |
| Living Art Tattoo Limited | Arts & recreation | 2006 |
| Living by Sophia Limited | Real estate | 2017 |
| Livingcare South West Ltd | Health & social care | 2012 |
| LIZ Rees Ltd | Professional & scientific | 2017 |
| LJ Lets Ltd | Real estate | 2026 |
| LJ Property Renovations Ltd | Construction | 2019 |
| LJB Consulting (South West) Ltd | Administrative & support | 2020 |
| LJN Plastering & Building Services Ltd | Construction | 2026 |
| LK Heating Solutions Ltd | Construction | 2024 |
| LK Hospitality Devon Limited | Hospitality | 2023 |
| Ll&Ll Ltd | Real estate | 2026 |
| Ll:Arch Limited | Professional & scientific | 2015 |
| Lleonard Limited | Wholesale & retail | 2025 |
| Llewella Ltd | Construction | 2020 |
| Llivoc Ltd | Real estate | 2023 |
| LLJ Property Limited | Households | 2024 |
| Lloyd M Bennett Ltd | Professional & scientific | 2023 |
| Lloyd's Refinishers Limited | Wholesale & retail | 2003 |
| Lloyds British Defence Ltd | Public administration | 2017 |
| Lloyds Rigging Lifting Testing Ltd | Manufacturing | 2017 |
| Lm-Pv Ltd | Construction | 2022 |
| LMA Trade Limited | Information & communication | 2009 |
| LMB Insurance Services Ltd | Financial services | 2017 |
| LMB Investments (SW) Ltd | Real estate | 2022 |
| LMG Properties (Plymouth) Limited | Real estate | 2023 |
| LMH Technical Services Limited | Construction | 2016 |
| Lmht Limited | Financial services | 2020 |
| LO & Behold Ltd | Administrative & support | 2022 |
| Loaf Consulting Limited | Hospitality | 2009 |
| Lock Electrical (SW) Ltd | Construction | 2023 |
| Lock Plymouth Ltd | Financial services | 2019 |
| Locke Lifting & Rigging Services Ltd | Construction | 2023 |
| Lockfield Limited | Real estate | 1998 |
| Lockington Anaesthesia Ltd | Health & social care | 2021 |
| Locksrite Limited | Extraterritorial | 2011 |
| Lockyer (Plymouth) Limited | Hospitality | 2014 |
| Locum Hands Ltd | Administrative & support | 2026 |
| Loddiswell Plant Hire Ltd | Administrative & support | 2026 |
| Lode Outdoors Ltd | Manufacturing | 2025 |
| Loft Transformers Limited | Construction | 2015 |
| Logan Lloyd Medical Ltd | Wholesale & retail | 2020 |
| Logical Constant Limited | Information & communication | 2023 |
| Logistics Management Consultancy Ltd | Professional & scientific | 2024 |
| Loki SOL Limited | Real estate | 2022 |
| Lomax Brown Ltd | Manufacturing | 2023 |
| London Braid Beauty Salon Ltd | Other services | 2021 |
| London Car Pro Ltd | Administrative & support | 2025 |
| London Electricity Technical Services Ltd | Construction | 2012 |
| London Entrepreneurs Network Limited | Education | 2013 |
| London Place Management Company Limited | Households | 2002 |
| London Transport Traction Group Ltd | Manufacturing | 2021 |
| Long View Ventures Limited | Professional & scientific | 2016 |
| Longlevens Window Repairs Ltd | Construction | 2011 |
| Longmeadow Court Management Company Limited | Households | 2007 |
| Lonsdale Villas Management Co Limited | Real estate | 2019 |
| Looe Storage Co. Ltd | Other services | 2020 |
| Loopypay Ltd | Manufacturing | 2023 |
| Looselabel Distribution Limited | Wholesale & retail | 2015 |
| Looselabel Limited | Wholesale & retail | 2015 |
| Loosen UP Ltd | Extraterritorial | 2004 |
| Lopez Nieto Ltd | Health & social care | 2015 |
| Lopsrus Limited | Financial services | 2022 |
| Lorcanela Ltd | Administrative & support | 2017 |
| Lord Nelson House Management Company Limited | Households | 1997 |
| Lords Pinnacle Fort Joinery & Glazing Ltd | Manufacturing | 2024 |
| Lords Pinnacle Group Ltd | Construction | 2021 |
| Lorenzo Properties Limited | Real estate | 2007 |
| Lorenzos (Plymouth) Limited | Hospitality | 2013 |
| Loretto (SW) Ltd | Hospitality | 2025 |
| Lorraine's Taxi Limited | Transport & logistics | 2021 |
| Lost in RIO Restaurant & Cocktail Bar Limited | Hospitality | 2024 |
| Lost in RIO Restaurant Ltd | Hospitality | 2022 |
| Lott Technical Services Limited | Professional & scientific | 2007 |
| Lotus Cleaning Services Ltd | Administrative & support | 2024 |
| Lotus Retail Consultants Limited | Wholesale & retail | 2017 |
| Louannon Menswear Limited | Wholesale & retail | 2012 |
| Loughtor Mill (Plympton) Management Company Limited | Households | 2023 |
| Louis Rayner Ltd | Professional & scientific | 2010 |
| Louis Rickard Consulting Ltd | Professional & scientific | 2026 |
| Louise Seddon Ltd | Education | 2017 |
| Louk Ltd | Information & communication | 2018 |
| Lovable Media Ltd | Professional & scientific | 2019 |
| Love & Sandcastles Ltd | Financial services | 2025 |
| Love Army HQ Ltd | Wholesale & retail | 2025 |
| Love Keep Create Textiles Limited | Manufacturing | 2010 |
| Love ME Ltd | Other services | 2026 |
| Lovekeepcreate Ltd | Manufacturing | 2019 |
| Lovely Hair Ltd | Wholesale & retail | 2021 |
| Loves Property Ltd | Real estate | 2019 |
| Lowe Henwood Limited | Professional & scientific | 2003 |