| Larson Holdings Limited | Financial services | 2024 |
| LAS Inns Limited | Hospitality | 2020 |
| Laser on Tour Plymouth Ltd | Other services | 2026 |
| Lashesbyemma Ltd | Other services | 2025 |
| Laskar Structures Ltd | Professional & scientific | 2018 |
| Last Chance Store Ltd | Wholesale & retail | 2017 |
| Latimer Roofing Limited | Construction | 2015 |
| Latitude 52 Management Company Limited | Households | 2003 |
| Latitude Aviation English Services Ltd | Education | 2013 |
| Launchpad Engine Ltd | Information & communication | 2012 |
| Launchpad Initiative Ltd | Real estate | 2026 |
| Laundry Partners Ltd | Other services | 2025 |
| LAUNDRY@55 Ltd | Other services | 2019 |
| Laura Louise Hall Weddings Ltd | Other services | 2024 |
| Laura Rudge Limited | Health & social care | 2008 |
| Laureates Smile Care Limited | Health & social care | 2024 |
| Laurus Sales Services Ltd | Other services | 2014 |
| Lavender Court Management Limited | Households | 1993 |
| Law Properties (SW) Ltd | Real estate | 2026 |
| Lawrence Locum Services Ltd | Health & social care | 2026 |
| Lawson (Plymouth) Limited | Real estate | 2003 |
| Lawson Grove Management Company Limited | Water & waste | 2000 |
| Lawtumn Legal Ltd | Professional & scientific | 2022 |
| Layers of Love Ltd | Manufacturing | 2026 |
| LB Accounting Services Ltd | Professional & scientific | 2018 |
| LB Ocean Consulting Ltd | Professional & scientific | 2026 |
| LB Tech Limited | Professional & scientific | 2020 |
| Lbilaw (862) Ltd | | 1957 |
| LBW Holdings Limited | Financial services | 2022 |
| LC Automation Group Limited | Professional & scientific | 2021 |
| LC Automation Holdings Limited | Professional & scientific | 2010 |
| LC Group (SW) Ltd | Construction | 2025 |
| LC Motorcycles Ltd | Administrative & support | 2023 |
| LC Plastering & Property Maintenance Limited | Construction | 2012 |
| LC Plymouth Limited | Hospitality | 2022 |
| LCB Carpentry & Building Ltd | Construction | 2025 |
| LCH (SW) Holdings Limited | Professional & scientific | 2012 |
| LCJ Project Management Limited | Professional & scientific | 2026 |
| LCK Leisure Limited | Hospitality | 2019 |
| LCL Marketing Limited | Administrative & support | 2018 |
| LCR Estates Ltd | Real estate | 2020 |
| Lcrsy Ltd | Wholesale & retail | 2025 |
| LD Building (SW) Ltd | Construction | 2026 |
| LDB Estates Limited | Real estate | 2023 |
| LDB IT Consultancy Limited | Information & communication | 2009 |
| LDN Digital Ltd | Professional & scientific | 2016 |
| LDR HR Limited | Administrative & support | 2019 |
| LDS Decorating Contractors Limited | Construction | 2012 |
| LE Vignoble Ltd | Wholesale & retail | 2012 |
| LEA Financial Services Limited | Financial services | 2008 |
| Lead Financial Limited | Financial services | 2017 |
| Lead Sleeve Ltd | Wholesale & retail | 2021 |
| Leading Lifestyles SW Limited | Hospitality | 2023 |
| Leading Regenerative Performance Ltd | Financial services | 2020 |
| Leadwell Ltd | Professional & scientific | 2025 |
| Leadworks Projects CIC | Other services | 2019 |
| Leaf IT OUT (SW) Ltd | Professional & scientific | 2023 |
| Leander Consultancy Ltd. | Manufacturing | 2018 |
| Leandra Restaurant Limited | Hospitality | 2005 |
| Leapersshoppers Ltd | Wholesale & retail | 2025 |
| Learn Online Video Ltd | Education | 2021 |
| Learning Academies Trust | Education | 2016 |
| Learning and Development Centre - Sentinel Limited | Education | 2017 |
| Learning Teams. Tech Ltd | Information & communication | 2026 |
| Learnity Group Limited | Education | 2025 |
| Learnmp Ltd | Education | 2026 |
| Lebafad Limited | Transport & logistics | 2026 |
| Lebanese Express Plymouth Limited | Hospitality | 2025 |
| Ledon Lets Ltd | Hospitality | 2017 |
| Ledon Ltd | Hospitality | 2016 |
| LEE & Co Estates Ltd | Real estate | 2025 |
| LEE Bickfords Food Limited | Hospitality | 2025 |
| LEE Ferris Design Limited | Professional & scientific | 2013 |
| LEE Fitness Limited | Other services | 2015 |
| LEE Hammond Mortgages Limited | Financial services | 2024 |
| LEE Hank Investments Limited | Real estate | 2025 |
| LEE Strathy Limited | Financial services | 2013 |
| Leeihmarh Beautyfix Ltd | Other services | 2025 |
| Leemill Offices Limited | Real estate | 2026 |
| Lees House of Hair Ltd | Other services | 2019 |
| Lees Plymouth Limited | Hospitality | 2023 |
| Leeward House (Mount Wise) RTM Company Limited | Households | 2025 |
| Legacy Beauty Lounge Ltd | Other services | 2023 |
| Legacy TCG SW Ltd | Wholesale & retail | 2025 |
| Legend Holidays Limited | Real estate | 2006 |
| Legendary Landscapes Limited | Administrative & support | 2016 |
| Legendary Lets LLP | | 2024 |
| Legends 4 Lease Ltd | Arts & recreation | 2025 |
| Legio Security Ltd | Administrative & support | 2020 |
| Leigh Visual Surveillance Systems Limited | Administrative & support | 1995 |
| Leigh-Anderson Associates Limited | Professional & scientific | 1998 |
| Leigham Manor Management (Plymouth) Limited | Households | 1988 |
| Lelec Automation Ltd | Manufacturing | 2025 |
| Lema Electrical Engineering Ltd | Construction | 2025 |
| Lema Mechanical Engineering Ltd | Construction | 2014 |
| Lemon Home Designs Ltd | Manufacturing | 2021 |
| LEN Solutions Limited | Information & communication | 2015 |
| Lennie Alexander Limited | Real estate | 2022 |
| Lensfield Properties Limited | Real estate | 1988 |
| LEO & Taurus Developments Limited | Construction | 2021 |