| D4S Health and Safety Ltd | Professional & scientific | 2024 |
| DA & SON Construction Ltd | Construction | 2024 |
| DA Electrical & Plumbing Services Ltd | Construction | 2015 |
| DA Interiors Ltd | Construction | 2022 |
| DA International Restaurants Ltd | Hospitality | 2024 |
| DAC Holdings (SW) Ltd | Real estate | 2025 |
| Dacres Holdings Ltd | Information & communication | 2019 |
| Dadzitis Consultancy Ltd | Other services | 2022 |
| Daften Holdings Limited | Financial services | 2025 |
| Daften Marketing Limited | Professional & scientific | 1985 |
| Daibri Services Ltd | Information & communication | 2022 |
| Dair Plymouth City Ltd | Hospitality | 2025 |
| Dairy Health Services International Limited | Professional & scientific | 2021 |
| Daisy Chains Healthcare Ltd | Health & social care | 2020 |
| Daisy Goord & Carly Brown Education Ltd | Education | 2026 |
| Daksh Shree Gems Ltd | Wholesale & retail | 2025 |
| Dalrymple-Hay Property Services Ltd | Real estate | 2026 |
| Dalton Heating Services Ltd | Construction | 2022 |
| Dalton Management Ltd | Real estate | 2019 |
| Damerell Developments Ltd | Construction | 2024 |
| Damerell’S Real Estate Holdings Ltd | Construction | 2022 |
| DAN Aquilina Electrical Ltd | Construction | 2021 |
| DAN Hunter Property Management Ltd | Households | 2025 |
| DAN Kelly Property Ltd | Real estate | 2025 |
| DAN Samways Truck Trailer Agri Plant Ltd | Wholesale & retail | 2025 |
| DAN Travel Ltd | Transport & logistics | 2024 |
| Dance for Life Devon CIC | Arts & recreation | 2023 |
| Danco Technology Limited | Information & communication | 1994 |
| Dane Hewings Scaffolding Ltd | Construction | 2025 |
| Danesther Limited | Administrative & support | 2014 |
| Dange Ltd | Construction | 2019 |
| Danidam Probeauty Mastery Ltd | Education | 2025 |
| Daniel Lewis Ltd | Other services | 2008 |
| Daniel Riley Design Ltd | Construction | 2020 |
| Daniel Surf Limited | Wholesale & retail | 2007 |
| Daniel Wall Photography Ltd | Professional & scientific | 2022 |
| Daniel's Detailing Co. Ltd | Wholesale & retail | 2025 |
| Daniela Tarau Ltd | Health & social care | 2013 |
| Danil Limited | Transport & logistics | 2020 |
| Dann Construction Ltd | Construction | 2024 |
| Danniyal Malik Limited | Real estate | 2010 |
| Danny Offshore Ltd | Mining & quarrying | 2019 |
| Danny Taylor Ltd | Construction | 2019 |
| Danpol Civils Ltd | Construction | 2021 |
| Darbyshire Care Limited | Health & social care | 2004 |
| Darbyshire Care Services Ltd | Extraterritorial | 2018 |
| Daringtobe Ltd | Health & social care | 2022 |
| Dark Knight Racing Ltd | Wholesale & retail | 2019 |
| Dark Marine Holdings Limited | Real estate | 2017 |
| Dark Mark Ltd | Transport & logistics | 2018 |
| Darklake Limited | Wholesale & retail | 2017 |
| Darkone Ltd | Arts & recreation | 2021 |
| Darlett Family Investment Company Limited | Real estate | 2021 |
| Darren Tolcher Plastering Ltd | Construction | 2021 |
| Darryl Studios Ltd | Arts & recreation | 2025 |
| Dart Sails and Covers Limited | Manufacturing | 2006 |
| Dartbox Ltd | Wholesale & retail | 2023 |
| Dartmoor Domes Ltd | Hospitality | 2020 |
| Dartmoor Specialist Building Services Limited | Construction | 2012 |
| Dartmoor Trust | Administrative & support | 1996 |
| Dartmoor Window Cleaning Limited | Administrative & support | 2021 |
| Dartmoor ZOO Enterprises Ltd | Hospitality | 2014 |
| Dartmoor Zoological Society | Arts & recreation | 2017 |
| Dartmouth Foods Ltd | Manufacturing | 2000 |
| Dartmouth Grove Ltd | Construction | 2019 |
| Dartmouth Grove Management Ltd. | Real estate | 2021 |
| Dartmouth Holdings Limited | Financial services | 2016 |
| Dartmouth Marine Ltd | Wholesale & retail | 2024 |
| Darts Connections Ltd | Wholesale & retail | 2025 |
| Dartview Management Company Limited | Households | 2007 |
| Daryl Knight Training Ltd | Education | 2025 |
| Dasina (UK) Limited | Other services | 1996 |
| Dats Carpentry Limited | Construction | 2019 |
| Davace Ltd | Information & communication | 2025 |
| Davaden Limited | Health & social care | 2024 |
| Dave's Boots & Shoes Limited | Manufacturing | 2011 |
| Davenport Aviation Limited | Manufacturing | 2019 |
| Davenport Construction and Development Ltd | Construction | 2013 |
| Davenport Estates and Investments Ltd | Real estate | 2024 |
| Davenport Holdings SW Ltd | Financial services | 2019 |
| Davenport Homes Ltd | Real estate | 2018 |
| Davey Group Limited | Professional & scientific | 2021 |
| Davey Wealth Management Ltd | Financial services | 2019 |
| David & David Limited | Other services | 2007 |
| David a Summers Limited | Professional & scientific | 2009 |
| David Ayre Cars Limited | Wholesale & retail | 2019 |
| David Gillespie Solutions Limited | Professional & scientific | 2011 |
| David MAY Motor Services Limited | Wholesale & retail | 2003 |
| David Oliver Podiatry Limited | Health & social care | 2003 |
| David Pinder & Co Limited | Administrative & support | 2009 |
| David the Builder Ltd | Construction | 2024 |
| David Tout Financial Solutions Ltd | Financial services | 2010 |
| Davina Stores Ltd | Wholesale & retail | 2011 |
| Davis Logistics Southwest Ltd | Transport & logistics | 2020 |
| Davker Ltd | Wholesale & retail | 2022 |
| Davmos Ltd | Financial services | 2016 |
| Davsam Limited | Real estate | 2024 |
| Davy Automotive Limited | Wholesale & retail | 2022 |
| Davy J Ltd | Manufacturing | 2016 |
| Davy Rental Properties Limited | Real estate | 2020 |