| Wisteria House Warwick Park Limited | Health & social care | 2024 |
| Wisteria House Woolwell Limited | Health & social care | 2021 |
| WISTERIA2024 Limited | Hospitality | 2024 |
| Wixen Court (SW) Management Company Limited | Households | 2003 |
| WK888 Ltd | Hospitality | 2025 |
| Wkuk (Plymouth) CIC | Administrative & support | 2014 |
| WM Property (SW) Ltd | Real estate | 2025 |
| WM Sales Ltd | Wholesale & retail | 2026 |
| WMM Group Ltd | Financial services | 2020 |
| WOK N Roll (Plymouth) Ltd | Hospitality | 2019 |
| Wolborough Street Management Company Ltd | Households | 2024 |
| Wolferstans LLP | | 2020 |
| WOLSDON51 Limited | Households | 2025 |
| Wolseley Community Economic Development Trust | Real estate | 1996 |
| Wolseley Road Takeaway Ltd | Hospitality | 2025 |
| Women's Leadership and Empowerment Network Ltd | Administrative & support | 2018 |
| Womenwhodontdrink CIC | Health & social care | 2022 |
| Wonda African Food Store Limited | Manufacturing | 2020 |
| Wonda Afro Carribean Restaurant and Bakery Ltd | Hospitality | 2023 |
| Wonderzoo CIC | Arts & recreation | 2020 |
| Wood Floor Solutions (South West) Limited | Construction | 2006 |
| Woodcote Close (Chagford) Ltd | Households | 2021 |
| Woodentoys Limited | Wholesale & retail | 2025 |
| Woodfield Properties (SW) Ltd | Real estate | 2025 |
| Woodland Fort Support Group C.I.C. | Health & social care | 2023 |
| Woodlands 1961 Limited | Extraterritorial | 2014 |
| Woodley Hotels (Dorchester) Ltd | Hospitality | 2023 |
| Woodley Hotels (Hampshire) Limited | Hospitality | 1988 |
| Woodley Hotels Limited | Hospitality | 1982 |
| Woodpecker Business Management Ltd | Real estate | 2022 |
| Woodpecker Business Park Limited | Construction | 2022 |
| Woodpecker Studios Ltd | Manufacturing | 2023 |
| Woodruff Property Investments Ltd | Real estate | 2021 |
| Woods Bistro Limited | Hospitality | 2015 |
| Woodside Animal Welfare Trust | Other services | 2011 |
| Woodside Court Management Company (Plympton) Limited | Households | 1994 |
| Woodside HFS Limited | Transport & logistics | 2026 |
| Woodwater Ltd | Health & social care | 2013 |
| Woody (Property) Limited | Construction | 2022 |
| Wooladon Estates Limited | Hospitality | 2021 |
| Woollcombe Yonge LLP | | 2016 |
| Woolwell Centre Limited | Wholesale & retail | 2012 |
| Woolwell Community Resource Trust | Hospitality | 1998 |
| Woolwell Fish Bar Limited | Hospitality | 2007 |
| Words, Words, Words Limited | Education | 2007 |
| Workforce Direct (Plymouth) LLP | | 2002 |
| Worktop Tech Ltd | Construction | 2016 |
| World Class Properties Ltd | Real estate | 2019 |
| World Class Sourcing Ltd | Real estate | 2019 |
| World Food SW Ltd | Hospitality | 2026 |
| World Pizza Limited | Hospitality | 2016 |
| World Riichi Limited | Professional & scientific | 2020 |
| Worth Building Construction Limited | Construction | 2022 |
| Worth Carpentry Limited | Construction | 2011 |
| Worth Groundworks Ltd | Construction | 2021 |
| Worthy Group Ltd | Extraterritorial | 2025 |
| Worthy House Limited | Construction | 2026 |
| Wren Devon Ltd | Wholesale & retail | 2025 |
| Wright Bakers Plymstock Ltd | Wholesale & retail | 2025 |
| Wright Clean Limited | Administrative & support | 2003 |
| Wright Close Limited | Households | 2005 |
| Wright Electrical Solutions SW Ltd | Construction | 2021 |
| Wright Fitz Limited | Information & communication | 2023 |
| Wright N2 Services Limited | Mining & quarrying | 2014 |
| Wrights Choice Flooring Ltd | Construction | 2022 |
| Wrights Jewellery Outlet Ltd | Wholesale & retail | 2016 |
| Writer Design & Build Limited | Construction | 2022 |
| WRS Cables Limited | Wholesale & retail | 2002 |
| WS Hygiene - Therapy Ltd | Health & social care | 2022 |
| Wstan Tech Ltd | Professional & scientific | 2022 |
| WTP Cleaning and Maintance Solutions Ltd | Administrative & support | 2025 |
| WU Academy Ltd | Wholesale & retail | 2017 |
| Wuber Limited | Water & waste | 2026 |
| Wuskin Investments Limited | Real estate | 1961 |
| WWA Productions Ltd | Arts & recreation | 2024 |
| Wyatt Brothers Funeral Directors Ltd | Other services | 2017 |
| Wykeham Homes (the Millfields) Limited | Professional & scientific | 2003 |
| Wynberry Ltd | Manufacturing | 2023 |
| Wyndham Lodge Maintenance Limited | Households | 1983 |
| Wyndham Property Services Ltd | Real estate | 2022 |
| X11 Consulting Limited | Information & communication | 2020 |
| XAN Mobile Tyres Limited | Wholesale & retail | 2026 |
| Xanti Ltd | Transport & logistics | 2005 |
| Xarri Limited | Households | 1984 |
| Xat.Com Limited | Information & communication | 1998 |
| Xclusive Tattoo Ltd | Other services | 2022 |
| XL Events Group Limited | Arts & recreation | 2018 |
| XL Site Services Limited | Professional & scientific | 2018 |
| Xlent Foods Limited | Wholesale & retail | 2002 |
| XON Fuels UK Limited | Wholesale & retail | 2018 |
| Xplorer Global Solution Limited | Information & communication | 2025 |
| Xtreme Cars and Motors Limited | Wholesale & retail | 2026 |
| Xtreme Partners Limited | Wholesale & retail | 2020 |
| Xynterra Ltd | Professional & scientific | 2025 |
| Y (36) Ltd | Administrative & support | 2008 |
| Y C 518 Plymouth Ltd | Hospitality | 2025 |
| Y-3 Fit OUT Ltd | Construction | 2023 |
| Y-3 Hoarding Systems Ltd | Construction | 2026 |
| Yacht Charter International Limited | Transport & logistics | 2009 |
| Yachting Lawyers Limited | Professional & scientific | 2019 |