| Skinfluence Peterborough Limited | Other services | 2022 |
| Skir Developments LLP | | 2023 |
| Skmk Aesthetic Ltd | Other services | 2022 |
| Skok Ltd | Transport & logistics | 2026 |
| Skopios Limited | Information & communication | 2026 |
| Skrt Vehicles Ltd | Wholesale & retail | 2021 |
| SKS Auto Services Limited | Wholesale & retail | 2005 |
| Skuil Ltd | Health & social care | 2018 |
| Sky Electronics Ltd | Wholesale & retail | 2024 |
| Sky Life Properties Ltd | Real estate | 2019 |
| Sky Property Management Services Ltd | Real estate | 2025 |
| Sky Revolutions Ltd | Professional & scientific | 2015 |
| Sky Sharma Foundation Limited | Other services | 2016 |
| Sky UK Enterprises Limited | Information & communication | 2020 |
| Skyblue Estates Limited | Real estate | 2021 |
| Skyblue Global Ltd | Wholesale & retail | 2026 |
| Skycorner Ltd | Wholesale & retail | 2024 |
| Skydale Ltd | Wholesale & retail | 2016 |
| Skydive MAG Limited | Information & communication | 2008 |
| Skye Investments Limited | Financial services | 1997 |
| Skyforge Farriery Ltd | Agriculture & fishing | 2026 |
| Skygate Holdings Limited | Real estate | 2021 |
| Skylark Residents Association Limited | Households | 2018 |
| Skylights One Ltd | Wholesale & retail | 2022 |
| Skyline Shipping Ltd | Wholesale & retail | 2024 |
| Skylink Outsource Ltd | Other services | 2025 |
| Skyways Logistics Ltd | Transport & logistics | 2023 |
| SL & JO Limited | Transport & logistics | 2018 |
| SL HCW Ltd | Other services | 2025 |
| SL Property Law Ltd | Professional & scientific | 2024 |
| Slate Barn Homes Limited | Construction | 2017 |
| Slater Property Holdings Limited | Real estate | 2026 |
| Slay Transport Ltd | Transport & logistics | 2021 |
| Slaybléu Ltd | Wholesale & retail | 2017 |
| Sleaford Car Centre Ltd | Wholesale & retail | 2023 |
| Sleepingroofs Ltd | Construction | 2021 |
| SLH Business Support Ltd | Administrative & support | 2025 |
| Slimal Health Care Limited | Health & social care | 2014 |
| Sline's Chops Limited | Health & social care | 2020 |
| Sliwa Transport Ltd | Transport & logistics | 2020 |
| SLJ Lettings Ltd | Real estate | 2023 |
| Sloan Plumb Wood LLP | | 2007 |
| Slothmove Ltd | Information & communication | 2019 |
| Slowow Ltd | Wholesale & retail | 2021 |
| SLS Property Consulting Limited | Real estate | 2024 |
| SLY Estates Limited | Real estate | 2021 |
| SLY Property Developments Limited | Extraterritorial | 2012 |
| SLY Property Management Limited | Real estate | 2019 |
| SM Delivers Limited | Transport & logistics | 2023 |
| SM Lettings Ltd | Real estate | 2025 |
| SM Motors Peterborough Ltd | Wholesale & retail | 2025 |
| SM24 Healthcare Limited | Administrative & support | 2021 |
| SM4RT Contracting Co Ltd | Professional & scientific | 2023 |
| SMA Wardrobes Ltd | Administrative & support | 2007 |
| Small Nose...Small Change C.I.C. | Arts & recreation | 2019 |
| Smallburn Land Limited | Financial services | 2023 |
| Smandar Interprise Limited | Wholesale & retail | 2023 |
| Smart 4 Fibre Ltd | Information & communication | 2021 |
| Smart Ace Tutoring Limited | Education | 2022 |
| Smart Business Coms Ltd | Administrative & support | 2016 |
| Smart Car Charge Limited | Construction | 2018 |
| Smart Courses Limited | Other services | 2025 |
| Smart Electrics and Maintenance Ltd | Construction | 2025 |
| Smart Forecourt Limited | Wholesale & retail | 2020 |
| Smart Global College for Online Education Ltd | Education | 2023 |
| Smart Home Charge Limited | Construction | 2018 |
| Smart Immigration Solutions Ltd | Professional & scientific | 2021 |
| Smart Invention Property Ltd | Real estate | 2021 |
| Smart Move Property Solutions ( UK ) Ltd | Real estate | 2016 |
| Smart Painting and Decorating Limited | Administrative & support | 2017 |
| Smart Phone Norfolk Ltd | Wholesale & retail | 2024 |
| Smart Qualifications Ltd | Education | 2017 |
| Smart Riviera Ltd | Other services | 2018 |
| Smart Routes Travel Ltd | Transport & logistics | 2026 |
| Smart Sales Management Limited | Financial services | 2004 |
| Smart Services DNS Limited | Construction | 2022 |
| Smart Sign (UK) Ltd | Manufacturing | 2013 |
| Smart Skiin Aesthetics Limited | Health & social care | 2023 |
| Smart Solutions GRP Limited | Professional & scientific | 2010 |
| Smart Solutions Management Limited | Professional & scientific | 2010 |
| Smart Spark Electrical Ltd | Professional & scientific | 2023 |
| Smart Step International Ltd | Professional & scientific | 2025 |
| Smart Technologies-Uk Ltd | Wholesale & retail | 2023 |
| Smart-Touch Renovations Ltd | Construction | 2024 |
| SMART4FUTURE Ltd | Education | 2022 |
| Smartai + UK LLP | | 2025 |
| Smartee Developments Limited | Construction | 2016 |
| Smarter Medical Services Limited | Real estate | 2013 |
| Smartfit Auto Centre Limited | Wholesale & retail | 2016 |
| Smartfit Fleet Management Limited | Wholesale & retail | 2016 |
| Smartfit Recovery Limited | Wholesale & retail | 2016 |
| Smartfone Norfolk Ltd | Other services | 2025 |
| Smartguru Ltd | Administrative & support | 2022 |
| Smartheat Plumbing and Heating Limited | Construction | 2008 |
| Smartmove Properties (Lettings) Ltd | Real estate | 2011 |
| Smartmove Properties (Peterborough) Ltd | Real estate | 2018 |
| Smartmove Properties (Yaxley) Ltd | Real estate | 2014 |
| Smartmove Properties(Maintenance) Ltd | Construction | 2021 |
| Smarton Technology Ltd | Information & communication | 2020 |
| Smartway Builders Limited | Construction | 2017 |