| R Holmes Engineering Ltd | Other services | 2023 |
| R L S Builders Limited | Wholesale & retail | 2002 |
| R M & S C Jenkinson Limited | Agriculture & fishing | 2014 |
| R M Jackson Limited | Other services | 2023 |
| R M Pumps (Cumbria) Limited | Manufacturing | 2000 |
| R Simpson TM Limited | Construction | 2024 |
| R. Brennand Engineering Limited | Construction | 2006 |
| R. H. Wilson (Lakes) Ltd. | Manufacturing | 2002 |
| R. J. H. Limited | Real estate | 1981 |
| Rabbit Hollow Property Limited | Real estate | 2019 |
| RAD Training Limited | Extraterritorial | 2010 |
| RAM Properties (North) Ltd | Real estate | 2019 |
| Rand Properties Limited | Construction | 2005 |
| Rapier Properties Limited | Construction | 2019 |
| Rayside Consultancy Limited | Construction | 2016 |
| RB7 Limited | Construction | 2014 |
| RC Civils Limited | Construction | 2016 |
| RC Tech Services Limited | Information & communication | 2019 |
| Rcft Limited | Agriculture & fishing | 2018 |
| Really Clever PR Ltd | Professional & scientific | 2011 |
| Rebanks Consulting Limited | Professional & scientific | 2003 |
| Red Admiral Rentals Limited | Real estate | 2025 |
| Red Door Stables Limited | Real estate | 2024 |
| Red News Limited | Wholesale & retail | 2005 |
| Red Street Limited | Real estate | 2005 |
| Red Street Property Consultancy Limited | Real estate | 2004 |
| Redhills Barn Fitness Ltd | Arts & recreation | 2023 |
| Redmed Offshore Ltd | Health & social care | 2024 |
| Redmond Rail Services Limited | Professional & scientific | 2014 |
| Reeds (Cumbria) Ltd | Manufacturing | 1915 |
| Reeds (PDS) Ltd | Manufacturing | 2024 |
| Refcom Certification Limited | Administrative & support | 2008 |
| Regen One Limited | Real estate | 2016 |
| Regent Two Limited | Arts & recreation | 2022 |
| Register of Mobility Scorers Limited | Agriculture & fishing | 2022 |
| REH Electrical Engineering Services Ltd | Professional & scientific | 2013 |
| Reliability Team Limited | Manufacturing | 1994 |
| Renewable Finance Solutions Limited | Energy | 2015 |
| Renvir Ltd | Manufacturing | 2025 |
| Renwick Bros. Limited | Construction | 2002 |
| Resolve Asbestos Management Ltd | Construction | 2016 |
| Resolvemydispute Limited | Extraterritorial | 2023 |
| Retail Project Associates Ltd | Professional & scientific | 2011 |
| Reubens Place Ltd | Hospitality | 2021 |
| REV 2 Race Limited | Wholesale & retail | 2009 |
| Revopsify Ltd | Professional & scientific | 2023 |
| Reynolds Medical Services Ltd | Health & social care | 2019 |
| Rhfenton Construction Limited | Construction | 2024 |
| Richardsons Funeral Directors Limited | Other services | 2004 |
| Ride in Progress Ltd | Information & communication | 2025 |
| Riggindale Limited | Real estate | 2002 |
| Ring Gate Enterprises Ltd | Health & social care | 2012 |
| RJR Croft Limited | Health & social care | 2026 |
| RLB Marketing Limited | Professional & scientific | 2025 |
| RM Project Management Services Ltd | Professional & scientific | 2020 |
| RMG Hygienist Ltd | Administrative & support | 2010 |
| RMT Slating Limited | Agriculture & fishing | 2001 |
| RNB Plumbing and Heating Limited | Construction | 2014 |
| ROB Blake UNI Solutions Limited | Information & communication | 2022 |
| Rob&Van Ltd | Transport & logistics | 2020 |
| Robin Taylforth Livestock Scanning Limited | Agriculture & fishing | 2017 |
| Robinson Udale Ltd | Professional & scientific | 2019 |
| Rogozin Ltd | Transport & logistics | 2025 |
| Ronrook Management Ltd | Professional & scientific | 2019 |
| Rookin House Activity Centre Ltd. | Arts & recreation | 1998 |
| Rosanna Elisabeth Ltd | Education | 2024 |
| Roseberry Cabins Limited | Manufacturing | 2016 |
| Rosedale Advisory Limited | Administrative & support | 2011 |
| Rowcliffe House Vets Limited | Professional & scientific | 2008 |
| ROY Perfect Limited | Wholesale & retail | 2001 |
| RR Health Care Limited | Health & social care | 2019 |
| RSM Property Developments Ltd | Construction | 2024 |
| RSM Property Maintenance Ltd | Construction | 2015 |
| Rubicon Films Limited | Information & communication | 2016 |
| Run Outdoors Ltd | Extraterritorial | 2021 |
| Russell Armer Group Limited | Professional & scientific | 2005 |
| Russell Armer Limited | Construction | 1961 |
| Ruth Clark Equestrian Ltd | Wholesale & retail | 2017 |
| Ruths Properties Ltd | Real estate | 2025 |
| Ryan Atkinson Plumbing & Heating Ltd | Construction | 2024 |
| Ryans Off-Licence Ltd | Wholesale & retail | 2021 |
| Rydal Hall Limited | Hospitality | 1990 |
| Rydal Hall Trading Limited | Hospitality | 2017 |
| Rydal Improvements Ltd | Construction | 2020 |
| Rynrew Ltd | Hospitality | 2005 |
| S & J Walker Limited | Agriculture & fishing | 2004 |
| S & R Hall Properties Limited | Real estate | 2025 |
| S H Curtis and Sons Limited | Real estate | 1971 |
| S P Dobinson Joinery Ltd | Professional & scientific | 2018 |
| S T C 8 Ltd | Hospitality | 2021 |
| S Ullyart Limited | Construction | 2011 |
| S W H Surveys Limited | Professional & scientific | 2002 |
| S&E Training & Development Ltd | Administrative & support | 2025 |
| S&T Cumbria Holdings Limited | Administrative & support | 2020 |
| S. J. Dudson Limited | Wholesale & retail | 2005 |
| S., C. & T. Bagot (Optometrists) Limited | Wholesale & retail | 2007 |
| S.I. & S. Hastings Limited | Transport & logistics | 2002 |
| Sabrina D&C Transport Ltd | Transport & logistics | 2025 |
| Sacred Space Foundation | Health & social care | 1989 |
| Saf-Wren Holdings Limited | Real estate | 2026 |